MPD: All measures mapped to paradigm code 'timecoh'

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Brinkmeyer1:33	Brinkmeyer1	RNA expression profiling	Theiler's murine encephalomyelitis virus	TMEV transcript abundance (normalized), post infection TMEV 64433 day 7 day 28	CC	4	both	4wks	N=1	2017

Graham1:1	Graham1	body weight	West Nile virus	body weight, post infection [g] bw 63301 day 0 day 3 day 6 day 8 day 9 day 10 day 11 day 12 day 13 day 14 (4 more)...	CC RIX	5	m	8-10wks	N=12	2015

Graham1:15	Graham1	health assessment	West Nile virus	clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection [score] clin_score 63315 day 0 day 3 day 6 day 8 day 9 day 10 day 11 day 12 day 13 day 14 (4 more)...	CC RIX	5	m	8-10wks	N=12	2015

Graham1:29	Graham1	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are CD4+ in brain, post infection [%] CD4_brain 63329 day 7 day 12 day 21 day 28	CC RIX	5	m	8-10wks	N=3	2015

Graham1:33	Graham1	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are CD4+ in spleen, post infection [%] CD4_spleen 63333 day 7 day 12 day 21 day 28	CC RIX	2	m	8-10wks	N=3	2015

Graham1:37	Graham1	immune cell quantification	West Nile virus	percentage of CD4+ T cells that are Foxp3+ in the brain, post infection [%] Treg_brain 63337 day 7 day 12 day 21 day 28	CC RIX	5	m	8-10wks	N=3	2015

Graham1:41	Graham1	immune cell quantification	West Nile virus	percentage of CD4+ T cells that are Foxp3+ in the spleen, post infection [%] Treg_spleen 63341 day 7 day 12 day 21 day 28	CC RIX	2	m	8-10wks	N=3	2015

Graham1:45	Graham1	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are CD8+ in brain, post infection [%] CD8_brain 63345 day 7 day 12 day 21 day 28	CC RIX	5	m	8-10wks	N=3	2015

Graham1:49	Graham1	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are CD8+ in spleen, post infection [%] CD8_spleen 63349 day 7 day 12 day 21 day 28	CC RIX	2	m	8-10wks	N=3	2015

Graham1:53	Graham1	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are NS4b+ in brain, post infection [%] NS4b_brain 63353 day 7 day 12 day 21 day 28	CC RIX	5	m	8-10wks	N=3	2015

Graham1:57	Graham1	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are NS4b+ in spleen, post infection [%] NS4b_spleen 63357 day 7 day 12 day 21 day 28	CC RIX	2	m	8-10wks	N=3	2015

Graham1:61	Graham1	immunoglobulin quantification	West Nile virus	virus-specific IgM in serum, post infection [ng/mL] WNV_IgM 63361 day 7 day 12 day 21 day 28	CC RIX	5	m	8-10wks	N=3	2015

Graham1:65	Graham1	RNA expression profiling	West Nile virus	virus in brain, fold change compared to matched control, post infection WNV_brain 63365 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham1:68	Graham1	RNA expression profiling	West Nile virus	virus in kidney, fold change compared to matched control, post infection WNV_kidney 63368 day 2 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham1:72	Graham1	RNA expression profiling	West Nile virus	virus in spleen, fold change compared to matched control, post infection WNV_spleen 63372 day 2 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham1:76	Graham1	RNA expression profiling	West Nile virus	Ifnb1 gene expression in brain, fold change compared to matched control, post infection Ifnb1_brain 63376 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham1:79	Graham1	RNA expression profiling	West Nile virus	Ifnb1 gene expression in kidney, fold change compared to matched control, post infection Ifnb1_kidney 63379 day 2 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham1:83	Graham1	RNA expression profiling	West Nile virus	Ifnb1 gene expression in spleen, fold change compared to matched control, post infection Ifnb1_spleen 63383 day 2 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham1:87	Graham1	RNA expression profiling	West Nile virus	Ifit1 gene expression in brain, fold change compared to matched control, post infection Ifit1_brain 63387 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham1:90	Graham1	RNA expression profiling	West Nile virus	Ifit1 gene expression in kidney, fold change compared to matched control, post infection Ifit1_kidney 63390 day 2 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham1:94	Graham1	RNA expression profiling	West Nile virus	Ifit1 gene expression in spleen, fold change compared to matched control, post infection Ifit1_spleen 63394 day 2 day 4 day 7 day 12	CC RIX	5	m	8-10wks	N=1	2015

Graham2:6	Graham2	in vitro assay	SARS-CoV	lung viral load titer (log10(x+1)), post infection [log(n)] log_titer 113790 post infection: day 2 day 4	CC RIX	111	f	8-10wks		2021

Noll1:26	Noll1	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin M (serum IgM) area under curve (AUC) post-infection [AUC] IgM 112602 post-infection: day 7 day 10 day 15 day 29 day 45	CC RIX	46	f	8-12 wks	N=4	2020

Noll1:31	Noll1	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G1 (serum IgG1) area under curve (AUC) post-infection [AUC] IgG1 112607 post-infection: day 7 day 10 day 15 day 29 day 45	CC RIX	46	f	8-12 wks	N=4	2020

Noll1:36	Noll1	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection [AUC] IgG2ac 112612 post-infection: day 7 day 10 day 15 day 29 day 45	CC RIX	46	f	8-12 wks	N=4	2020

Noll1:41	Noll1	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G2b (serum IgG2b) area under curve (AUC) post-infection [AUC] IgG2b 112617 post-infection: day 7 day 10 day 15 day 29 day 45	CC RIX	46	f	8-12 wks	N=3	2020

Noll1:46	Noll1	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection [AUC] IgG3 112622 post-infection: day 7 day 10 day 15 day 29 day 45	CC RIX	46	f	8-12 wks	N=4	2020

Noll1:51	Noll1	immunoglobulin quantification	influenza A (H1N1) virus	total immunoglobulin G (serum IgG) area under curve (AUC) post-infection [AUC] Total_IgG 112627 post-infection: day 7 day 10 day 15 day 29 day 45	CC RIX	44	f	8-12 wks	N=3	2020

Rusyn2:12	Rusyn2	metabolic panel	trichloroethylene	alanine transaminase (serum ALT), control group [IU/L] ALT_ctrl 36112 time: 2h 8h 24h	inbred	17	m	7wks	N=3	2010

Rusyn2:17	Rusyn2	metabolic panel	trichloroethylene	alanine transaminase (serum ALT), treated group [IU/L] ALT_tce 36117 time: 2h 8h 24h	inbred	17	m	7wks	N=3	2010

Rusyn2:22	Rusyn2	metabolic panel	trichloroethylene	aspartate transaminase (serum AST), control group [IU/L] AST_ctrl 36122 time: 2h 8h 24h	inbred	16	m	7wks	N=3	2010

Rusyn2:27	Rusyn2	metabolic panel	trichloroethylene	aspartate transaminase (serum AST), treated group [IU/L] AST_tce 36127 time: 2h 8h 24h	inbred	16	m	7wks	N=3	2010

Rusyn2:32	Rusyn2	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN), control group [mg/dL] BUN_ctrl 36132 time: 2h 8h 24h	inbred	16	m	7wks	N=3	2010

Rusyn2:37	Rusyn2	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN), treated group [mg/dL] BUN_tce 36137 time: 2h 8h 24h	inbred	16	m	7wks	N=3	2010

Rusyn2:67	Rusyn2	drug and metabolite quantification	trichloroethylene	dichloroacetic acid (serum DCA x 10^-3) [nmol/mL] DCA_tce 36167 time after treatment: 2h 8h 24h	inbred	15	m	7wks	N=3	2010

Rusyn2:75	Rusyn2	drug and metabolite quantification	trichloroethylene	trichloroacetic acid (serum TCA) [nmol/mL] TCA_tce 36175 time after treatment: 2h 8h 24h	inbred	15	m	7wks	N=3	2010

Rusyn2:85	Rusyn2	drug and metabolite quantification	trichloroethylene	DCV cysteine (serum DCVC x 10^-3) [nmol/mL] DCV_cysteine_tce 36185 time after treatment: 2h 8h 24h	inbred	16	m	7wks	N=2	2010

Rusyn2:95	Rusyn2	drug and metabolite quantification	trichloroethylene	DCV glutathione (serum DCVG x 10^-3) [nmol/mL] DCV_glutathione_tce 36195 time after treatment: 2h 8h 24h	inbred	17	m	7wks	N=2	2010

Schughart5:83	Schughart5	organ weights	influenza A (H3N2) virus	lung weight, treated group [g] lungwt_trt 58883 days post-infection: 3 5 8 18 30	inbred w/CC8	8	f	10wks	N=4	2016

Schughart5:93	Schughart5	organ weights	influenza A (H3N2) virus	relative lung weight, treated group [%] lungwtadj_trt 58893 days post-infection: 3 5 8 18 30	inbred w/CC8	8	f	10wks	N=4	2016

Brinkmeyer1

RNA expression profiling

Theiler's murine encephalomyelitis virus

TMEV transcript abundance (normalized), post infection TMEV 64433 day 7 day 28

CC

4

both

4wks

N=1

2017

Graham1

body weight

West Nile virus

body weight, post infection [g] bw 63301 day 0 day 3 day 6 day 8 day 9 day 10 day 11 day 12 day 13 day 14 (4 more)...

CC RIX

5

m

8-10wks

N=12

2015

Graham1

health assessment

West Nile virus

clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection [score] clin_score 63315 day 0 day 3 day 6 day 8 day 9 day 10 day 11 day 12 day 13 day 14 (4 more)...

CC RIX

5

m

8-10wks

N=12

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD3+ T cells that are CD4+ in brain, post infection [%] CD4_brain 63329 day 7 day 12 day 21 day 28

CC RIX

5

m

8-10wks

N=3

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD3+ T cells that are CD4+ in spleen, post infection [%] CD4_spleen 63333 day 7 day 12 day 21 day 28

CC RIX

2

m

8-10wks

N=3

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD4+ T cells that are Foxp3+ in the brain, post infection [%] Treg_brain 63337 day 7 day 12 day 21 day 28

CC RIX

5

m

8-10wks

N=3

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD4+ T cells that are Foxp3+ in the spleen, post infection [%] Treg_spleen 63341 day 7 day 12 day 21 day 28

CC RIX

2

m

8-10wks

N=3

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD3+ T cells that are CD8+ in brain, post infection [%] CD8_brain 63345 day 7 day 12 day 21 day 28

CC RIX

5

m

8-10wks

N=3

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD3+ T cells that are CD8+ in spleen, post infection [%] CD8_spleen 63349 day 7 day 12 day 21 day 28

CC RIX

2

m

8-10wks

N=3

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD3+ T cells that are NS4b+ in brain, post infection [%] NS4b_brain 63353 day 7 day 12 day 21 day 28

CC RIX

5

m

8-10wks

N=3

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD3+ T cells that are NS4b+ in spleen, post infection [%] NS4b_spleen 63357 day 7 day 12 day 21 day 28

CC RIX

2

m

8-10wks

N=3

2015

Graham1

immunoglobulin quantification

West Nile virus

virus-specific IgM in serum, post infection [ng/mL] WNV_IgM 63361 day 7 day 12 day 21 day 28

CC RIX

5

m

8-10wks

N=3

2015

Graham1

RNA expression profiling

West Nile virus

virus in brain, fold change compared to matched control, post infection WNV_brain 63365 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham1

RNA expression profiling

West Nile virus

virus in kidney, fold change compared to matched control, post infection WNV_kidney 63368 day 2 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham1

RNA expression profiling

West Nile virus

virus in spleen, fold change compared to matched control, post infection WNV_spleen 63372 day 2 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham1

RNA expression profiling

West Nile virus

Ifnb1 gene expression in brain, fold change compared to matched control, post infection Ifnb1_brain 63376 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham1

RNA expression profiling

West Nile virus

Ifnb1 gene expression in kidney, fold change compared to matched control, post infection Ifnb1_kidney 63379 day 2 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham1

RNA expression profiling

West Nile virus

Ifnb1 gene expression in spleen, fold change compared to matched control, post infection Ifnb1_spleen 63383 day 2 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham1

RNA expression profiling

West Nile virus

Ifit1 gene expression in brain, fold change compared to matched control, post infection Ifit1_brain 63387 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham1

RNA expression profiling

West Nile virus

Ifit1 gene expression in kidney, fold change compared to matched control, post infection Ifit1_kidney 63390 day 2 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham1

RNA expression profiling

West Nile virus

Ifit1 gene expression in spleen, fold change compared to matched control, post infection Ifit1_spleen 63394 day 2 day 4 day 7 day 12

CC RIX

5

m

8-10wks

N=1

2015

Graham2

in vitro assay

SARS-CoV

lung viral load titer (log10(x+1)), post infection [log(n)] log_titer 113790 post infection: day 2 day 4

CC RIX

111

f

8-10wks

2021

Noll1

immunoglobulin quantification

influenza A (H1N1) virus

immunoglobulin M (serum IgM) area under curve (AUC) post-infection [AUC] IgM 112602 post-infection: day 7 day 10 day 15 day 29 day 45

CC RIX

46

f

8-12 wks

N=4

2020

Noll1

immunoglobulin quantification

influenza A (H1N1) virus

immunoglobulin G1 (serum IgG1) area under curve (AUC) post-infection [AUC] IgG1 112607 post-infection: day 7 day 10 day 15 day 29 day 45

CC RIX

46

f

8-12 wks

N=4

2020

Noll1

immunoglobulin quantification

influenza A (H1N1) virus

immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection [AUC] IgG2ac 112612 post-infection: day 7 day 10 day 15 day 29 day 45

CC RIX

46

f

8-12 wks

N=4

2020

Noll1

immunoglobulin quantification

influenza A (H1N1) virus

immunoglobulin G2b (serum IgG2b) area under curve (AUC) post-infection [AUC] IgG2b 112617 post-infection: day 7 day 10 day 15 day 29 day 45

CC RIX

46

f

8-12 wks

N=3

2020

Noll1

immunoglobulin quantification

influenza A (H1N1) virus

immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection [AUC] IgG3 112622 post-infection: day 7 day 10 day 15 day 29 day 45

CC RIX

46

f

8-12 wks

N=4

2020

Noll1

immunoglobulin quantification

influenza A (H1N1) virus

total immunoglobulin G (serum IgG) area under curve (AUC) post-infection [AUC] Total_IgG 112627 post-infection: day 7 day 10 day 15 day 29 day 45

CC RIX

44

f

8-12 wks

N=3

2020

Rusyn2

metabolic panel

trichloroethylene

alanine transaminase (serum ALT), control group [IU/L] ALT_ctrl 36112 time: 2h 8h 24h

inbred

17

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

alanine transaminase (serum ALT), treated group [IU/L] ALT_tce 36117 time: 2h 8h 24h

inbred

17

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

aspartate transaminase (serum AST), control group [IU/L] AST_ctrl 36122 time: 2h 8h 24h

inbred

16

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

aspartate transaminase (serum AST), treated group [IU/L] AST_tce 36127 time: 2h 8h 24h

inbred

16

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

blood urea nitrogen (serum BUN), control group [mg/dL] BUN_ctrl 36132 time: 2h 8h 24h

inbred

16

m

7wks

N=3

2010

Rusyn2

metabolic panel

trichloroethylene

blood urea nitrogen (serum BUN), treated group [mg/dL] BUN_tce 36137 time: 2h 8h 24h

inbred

16

m

7wks

N=3

2010

Rusyn2

drug and metabolite quantification

trichloroethylene

dichloroacetic acid (serum DCA x 10^-3) [nmol/mL] DCA_tce 36167 time after treatment: 2h 8h 24h

inbred

15

m

7wks

N=3

2010

Rusyn2

drug and metabolite quantification

trichloroethylene

trichloroacetic acid (serum TCA) [nmol/mL] TCA_tce 36175 time after treatment: 2h 8h 24h

inbred

15

m

7wks

N=3

2010

Rusyn2

drug and metabolite quantification

trichloroethylene

DCV cysteine (serum DCVC x 10^-3) [nmol/mL] DCV_cysteine_tce 36185 time after treatment: 2h 8h 24h

inbred

16

m

7wks

N=2

2010

Rusyn2

drug and metabolite quantification

trichloroethylene

DCV glutathione (serum DCVG x 10^-3) [nmol/mL] DCV_glutathione_tce 36195 time after treatment: 2h 8h 24h

inbred

17

m

7wks

N=2

2010

Schughart5

organ weights

influenza A (H3N2) virus

lung weight, treated group [g] lungwt_trt 58883 days post-infection: 3 5 8 18 30

inbred w/CC8

8

f

10wks

N=4

2016

Schughart5

organ weights

influenza A (H3N2) virus

relative lung weight, treated group [%] lungwtadj_trt 58893 days post-infection: 3 5 8 18 30

inbred w/CC8

8

f

10wks

N=4

2016

Study designs: all MPD measure sets of study design type timecoh

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