Project measure / variable:   Paigen3   mucin

ID, description, units MPD:2809   mucin   gallbladder, mucin (score: 0-4)   [score]  
high-fat diet study
Data set, strains Paigen3   obesity mutants   7 strains     sex: both     age: 15-19wks
Procedure histopathology
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  STRAIN COMPARISON PLOT
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Paigen3 - gallbladder, mucin (score: 0-4)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means1.48   score 1.58   score
Median of the strain means1.33   score 1.56   score
SD of the strain means± 0.569 ± 0.584
Coefficient of variation (CV)0.385 0.369
Min–max range of strain means0.750   –   2.38   score 1.00   –   2.78   score
Mean sample size per strain7.7   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1272 0.1272 0.235 0.6289
strain 6 29.9913 4.9985 9.2325 < 0.0001
sex:strain 6 1.6351 0.2725 0.5033 0.8045
Residuals 97 52.5167 0.5414


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6(AU)-Tubtub/J f 1.33 1.09   9 0.363 0.817 0.5, 4.0 -0.26
B6(AU)-Tubtub/J m 1.56 0.527   9 0.176 0.339 1.0, 2.0 -0.04
B6.Cg-Ay/J f 1.2 0.447   5 0.2 0.373 1.0, 2.0 -0.49
B6.Cg-Ay/J m 1.25 0.54   10 0.171 0.432 0.5, 2.0 -0.57
B6.Cg-Lepob/J f 1.0 0.0   7 0.0 0.0 1.0, 1.0 -0.84
B6.Cg-Lepob/J m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -1.0
BKS.Cg-Dock7m +/+ Leprdb/J f 1.78 0.667   9 0.222 0.375 1.0, 3.0 0.53
BKS.Cg-Dock7m +/+ Leprdb/J m 1.7 0.483   10 0.153 0.284 1.0, 2.0 0.2
BKSChpLt.HRS-Cpefat/J f 2.38 1.41   8 0.498 0.593 1.0, 4.0 1.59
BKSChpLt.HRS-Cpefat/J m 2.78 1.09   9 0.364 0.393 1.0, 4.0 2.05
C57BL/6J f 1.9 0.738   10 0.233 0.388 1.0, 3.0 0.74
C57BL/6J m 1.58 0.665   6 0.271 0.42 0.5, 2.0 0.0
C57BLKS/J f 0.75 0.274   6 0.112 0.365 0.5, 1.0 -1.28
C57BLKS/J m 1.2 0.447   5 0.2 0.373 1.0, 2.0 -0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J f 1.3333 0.2453 1.8201 0.8465
B6(AU)-Tubtub/J m 1.5556 0.2453 2.0423 1.0688
B6.Cg-Ay/J f 1.2 0.3291 1.8531 0.5469
B6.Cg-Ay/J m 1.25 0.2327 1.7118 0.7882
B6.Cg-Lepob/J f 1.0 0.2781 1.552 0.448
B6.Cg-Lepob/J m 1.0 0.2601 1.5163 0.4837
BKS.Cg-Dock7m +/+ Leprdb/J f 1.7778 0.2453 2.2646 1.291
BKS.Cg-Dock7m +/+ Leprdb/J m 1.7 0.2327 2.1618 1.2382
BKSChpLt.HRS-Cpefat/J f 2.375 0.2601 2.8913 1.8587
BKSChpLt.HRS-Cpefat/J m 2.7778 0.2453 3.2646 2.291
C57BL/6J f 1.9 0.2327 2.3618 1.4382
C57BL/6J m 1.5833 0.3004 2.1795 0.9871
C57BLKS/J f 0.75 0.3004 1.3462 0.1538
C57BLKS/J m 1.2 0.3291 1.8531 0.5469


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J both 1.4444 0.1734 1.7887 1.1002
B6.Cg-Ay/J both 1.225 0.2015 1.6249 0.8251
B6.Cg-Lepob/J both 1.0 0.1904 1.3779 0.6221
BKS.Cg-Dock7m +/+ Leprdb/J both 1.7389 0.169 2.0744 1.4034
BKSChpLt.HRS-Cpefat/J both 2.5764 0.1788 2.9312 2.2216
C57BL/6J both 1.7417 0.19 2.1187 1.3646
C57BLKS/J both 0.975 0.2228 1.4171 0.5329




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA