Phenotype measure:   Paigen3   nstones

ID, description, units MPD:2818   nstones   gallbladder, number of sandy plus true stones   [n]   measure
high-fat diet study
Data set, strains Paigen3   obesity mutants   7 strains     sex: both     age: 15-19wks
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Paigen3 - gallbladder, number of sandy plus true stones



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means0.834   n 4.82   n
Median of the strain means0.200   n 1.11   n
SD of the strain means± 1.31 ± 6.79
Coefficient of variation (CV)1.57 1.41
Min–max range of strain means0   –   3.38   n 0   –   18.3   n
Mean sample size per strain7.7   mice 8.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 576.9336 576.9336 6.507 0.0123
strain 6 1794.8386 299.1398 3.3739 0.0046
sex:strain 6 877.6994 146.2832 1.6499 0.1416
Residuals 98 8689.0194 88.6635


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6(AU)-Tubtub/J f 1.89 4.28   9 1.43 2.27 0.81
B6(AU)-Tubtub/J m 1.11 3.33   9 1.11 3.0 -0.55
B6.Cg-Ay/J f 0.2 0.447   5 0.2 2.24 -0.49
B6.Cg-Ay/J m 9.0 13.1   10 4.14 1.46 0.62
B6.Cg-Lepob/J f 0.0 0.0   7 0.0 0.0 -0.64
B6.Cg-Lepob/J m 0.25 0.463   8 0.164 1.85 -0.67
BKS.Cg-Dock7m +/+ Leprdb/J f 0.0 0.0   9 0.0 0.0 -0.64
BKS.Cg-Dock7m +/+ Leprdb/J m 0.0 0.0   10 0.0 0.0 -0.71
BKSChpLt.HRS-Cpefat/J f 3.38 8.37   8 2.96 2.48 1.95
BKSChpLt.HRS-Cpefat/J m 18.3 26.5   10 8.39 1.45 1.99
C57BL/6J f 0.2 0.632   10 0.2 3.16 -0.49
C57BL/6J m 4.67 4.08   6 1.67 0.875 -0.02
C57BLKS/J f 0.167 0.408   6 0.167 2.45 -0.51
C57BLKS/J m 0.4 0.548   5 0.245 1.37 -0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J f 1.8889 3.1387 8.1176 -4.3398
B6(AU)-Tubtub/J m 1.1111 3.1387 7.3398 -5.1176
B6.Cg-Ay/J f 0.2 4.211 8.5566 -8.1566
B6.Cg-Ay/J m 9.0 2.9776 14.909 3.091
B6.Cg-Lepob/J f 0.0 3.559 7.0626 -7.0626
B6.Cg-Lepob/J m 0.25 3.3291 6.8565 -6.3565
BKS.Cg-Dock7m +/+ Leprdb/J f 0.0 3.1387 6.2287 -6.2287
BKS.Cg-Dock7m +/+ Leprdb/J m 0.0 2.9776 5.909 -5.909
BKSChpLt.HRS-Cpefat/J f 3.375 3.3291 9.9815 -3.2315
BKSChpLt.HRS-Cpefat/J m 18.3 2.9776 24.209 12.391
C57BL/6J f 0.2 2.9776 6.109 -5.709
C57BL/6J m 4.6667 3.8441 12.2952 -2.9619
C57BLKS/J f 0.1667 3.8441 7.7952 -7.4619
C57BLKS/J m 0.4 4.211 8.7566 -7.9566


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J both 1.5 2.2194 5.9043 -2.9043
B6.Cg-Ay/J both 4.6 2.5787 9.7174 -0.5174
B6.Cg-Lepob/J both 0.125 2.4367 4.9605 -4.7105
BKS.Cg-Dock7m +/+ Leprdb/J both 0.0 2.1632 4.2928 -4.2928
BKSChpLt.HRS-Cpefat/J both 10.8375 2.2332 15.2693 6.4057
C57BL/6J both 2.4333 2.4312 7.258 -2.3914
C57BLKS/J both 0.2833 2.8509 5.9408 -5.3741




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA