Project measure / variable:   Paigen3   gs

ID, description, units MPD:2817   gs   gallbladder, number of true gallstones   [n]  
high-fat diet study
Data set, strains Paigen3   obesity mutants   7 strains     sex: both     age: 15-19wks
Procedure histopathology
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen3 - gallbladder, number of true gallstones



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means0.498   n 2.82   n
Median of the strain means0   n 1.11   n
SD of the strain means± 0.806 ± 4.46
Coefficient of variation (CV)1.62 1.58
Min–max range of strain means0   –   1.88   n 0   –   12.4   n
Mean sample size per strain7.7   mice 8.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 199.3336 199.3336 4.8802 0.0295
strain 6 758.7273 126.4546 3.096 0.0081
sex:strain 6 399.3964 66.5661 1.6297 0.147
Residuals 98 4002.8194 40.8451


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6(AU)-Tubtub/J f 1.44 4.33   9 1.44 3.0 1.17
B6(AU)-Tubtub/J m 1.11 3.33   9 1.11 3.0 -0.38
B6.Cg-Ay/J f 0.0 0.0   5 0.0 0.0 -0.62
B6.Cg-Ay/J m 3.7 9.32   10 2.95 2.52 0.2
B6.Cg-Lepob/J f 0.0 0.0   7 0.0 0.0 -0.62
B6.Cg-Lepob/J m 0.0 0.0   8 0.0 0.0 -0.63
BKS.Cg-Dock7m +/+ Leprdb/J f 0.0 0.0   9 0.0 0.0 -0.62
BKS.Cg-Dock7m +/+ Leprdb/J m 0.0 0.0   10 0.0 0.0 -0.63
BKSChpLt.HRS-Cpefat/J f 1.88 4.16   8 1.47 2.22 1.71
BKSChpLt.HRS-Cpefat/J m 12.4 17.7   10 5.58 1.42 2.15
C57BL/6J f 0.0 0.0   10 0.0 0.0 -0.62
C57BL/6J m 2.5 3.27   6 1.34 1.31 -0.07
C57BLKS/J f 0.167 0.408   6 0.167 2.45 -0.41
C57BLKS/J m 0.0 0.0   5 0.0 0.0 -0.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J f 1.4444 2.1303 5.672 -2.7831
B6(AU)-Tubtub/J m 1.1111 2.1303 5.3387 -3.1165
B6.Cg-Ay/J f 0.0 2.8581 5.6719 -5.6719
B6.Cg-Ay/J m 3.7 2.021 7.7106 -0.3106
B6.Cg-Lepob/J f 0.0 2.4156 4.7936 -4.7936
B6.Cg-Lepob/J m 0.0 2.2596 4.484 -4.484
BKS.Cg-Dock7m +/+ Leprdb/J f 0.0 2.1303 4.2276 -4.2276
BKS.Cg-Dock7m +/+ Leprdb/J m 0.0 2.021 4.0106 -4.0106
BKSChpLt.HRS-Cpefat/J f 1.875 2.2596 6.359 -2.609
BKSChpLt.HRS-Cpefat/J m 12.4 2.021 16.4106 8.3894
C57BL/6J f 0.0 2.021 4.0106 -4.0106
C57BL/6J m 2.5 2.6091 7.6777 -2.6777
C57BLKS/J f 0.1667 2.6091 5.3444 -5.0111
C57BLKS/J m 0.0 2.8581 5.6719 -5.6719


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J both 1.2778 1.5064 4.2671 -1.7116
B6.Cg-Ay/J both 1.85 1.7503 5.3233 -1.6233
B6.Cg-Lepob/J both 0.0 1.6538 3.282 -3.282
BKS.Cg-Dock7m +/+ Leprdb/J both 0.0 1.4682 2.9137 -2.9137
BKSChpLt.HRS-Cpefat/J both 7.1375 1.5158 10.1455 4.1295
C57BL/6J both 1.25 1.6502 4.5247 -2.0247
C57BLKS/J both 0.0833 1.935 3.9232 -3.7566




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA