Phenotype measure

ID, description, units MPD:2822   nonHDL_Ch   plasma cholesterol not in the HDL fraction   [mg/dL]
high-fat diet study
Data set, strains Paigen3   obesity mutants   8 strains     sex: both     age: 15-19wks
Procedure lipid profile
Ontology mappings


  STRAIN COMPARISON PLOT
width:   ×  height:  pixels

Paigen3 - plasma cholesterol not in the HDL fraction



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains8 strains
Mean of the strain means191   mg/dL 203   mg/dL
Median of the strain means133   mg/dL 184   mg/dL
SD of the strain means± 85.4 ± 80.6
Coefficient of variation (CV)0.446 0.398
Min–max range of strain means109   –   300   mg/dL 118   –   334   mg/dL
Mean sample size per strain17.6   mice 14.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 19.1335 19.1335 0.0047 0.9455
strain 6 1024621.5633 170770.2605 41.7661 < 0.0001
sex:strain 6 203466.3509 33911.0585 8.2938 < 0.0001
Residuals 223 911786.0747 4088.7268


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.BKS(D)-Leprdb/J m 334.0 65.3   4 32.7 0.196 290.0, 431.0 1.63
B6.Cg-Ay/J f 133.0 40.4   18 9.52 0.304 41.0, 251.0 -0.68
B6.Cg-Ay/J m 162.0 28.5   16 7.13 0.176 120.0, 206.0 -0.5
B6.Cg-Lepob/J f 300.0 107.0   16 26.7 0.356 157.0, 502.0 1.27
B6.Cg-Lepob/J m 309.0 96.7   18 22.8 0.312 185.0, 519.0 1.32
B6(Cg)-Tubtub/J f 132.0 29.1   21 6.35 0.22 90.0, 187.0 -0.7
B6(Cg)-Tubtub/J m 122.0 21.5   20 4.8 0.177 88.0, 159.0 -1.0
BKS.Cg-Dock7m +/+ Leprdb/J f 294.0 132.0   18 31.0 0.448 64.0, 474.0 1.2
BKS.Cg-Dock7m +/+ Leprdb/J m 163.0 69.1   15 17.9 0.425 55.0, 288.0 -0.49
BKSChpLt.HRS-Cpefat/J f 248.0 67.5   13 18.7 0.272 175.0, 440.0 0.66
BKSChpLt.HRS-Cpefat/J m 208.0 48.3   15 12.5 0.232 142.0, 285.0 0.07
C57BL/6J f 124.0 20.5   13 5.69 0.165 80.0, 153.0 -0.79
C57BL/6J m 205.0 39.3   15 10.1 0.192 133.0, 280.0 0.03
C57BLKS/J f 109.0 30.8   24 6.28 0.281 62.0, 169.0 -0.96
C57BLKS/J m 118.0 36.5   15 9.42 0.309 74.0, 191.0 -1.05


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.Cg-Ay/J f 132.7778 15.0715 162.4787 103.0769
B6.Cg-Ay/J m 162.3125 15.9858 193.815 130.81
B6.Cg-Lepob/J f 300.125 15.9858 331.6275 268.6225
B6.Cg-Lepob/J m 309.4444 15.0715 339.1453 279.7436
B6(Cg)-Tubtub/J f 132.0 13.9535 159.4977 104.5023
B6(Cg)-Tubtub/J m 121.5 14.2981 149.6767 93.3233
BKS.Cg-Dock7m +/+ Leprdb/J f 294.2222 15.0715 323.9231 264.5213
BKS.Cg-Dock7m +/+ Leprdb/J m 162.6667 16.5101 195.2023 130.131
BKSChpLt.HRS-Cpefat/J f 248.3846 17.7346 283.3335 213.4357
BKSChpLt.HRS-Cpefat/J m 208.2 16.5101 240.7357 175.6643
C57BL/6J f 124.3846 17.7346 159.3335 89.4357
C57BL/6J m 204.6 16.5101 237.1357 172.0643
C57BLKS/J f 109.3333 13.0523 135.055 83.6116
C57BLKS/J m 118.2 16.5101 150.7357 85.6643


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.Cg-Ay/J both 147.5451 10.9852 169.1932 125.8971
B6.Cg-Lepob/J both 304.7847 10.9852 326.4328 283.1367
B6(Cg)-Tubtub/J both 126.75 9.9892 146.4353 107.0647
BKS.Cg-Dock7m +/+ Leprdb/J both 228.4444 11.1774 250.4712 206.4177
BKSChpLt.HRS-Cpefat/J both 228.2923 12.1151 252.167 204.4176
C57BL/6J both 164.4923 12.1151 188.367 140.6176
C57BLKS/J both 113.7667 10.5231 134.5042 93.0292