Project measure / variable:   Paigen3   gbvol

ID, description, units MPD:2808   gbvol   gallbladder volume   [µL]  
high-fat diet study
Data set, strains Paigen3   obesity mutants   8 strains     sex: both     age: 15-19wks
Procedure organ dimensions
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen3 - gallbladder volume



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains8 strains
Mean of the strain means19.0   µL 27.9   µL
Median of the strain means20.3   µL 27.4   µL
SD of the strain means± 8.72 ± 16.0
Coefficient of variation (CV)0.460 0.573
Min–max range of strain means7.45   –   32.2   µL 10.1   –   55.0   µL
Mean sample size per strain17.0   mice 18.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3087.0678 3087.0678 20.2908 < 0.0001
strain 6 26851.5091 4475.2515 29.4151 < 0.0001
sex:strain 6 2858.6936 476.4489 3.1316 0.0057
Residuals 237 36057.4923 152.1413


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6(AU)-Tubtub/J f 20.3 9.69   21 2.11 0.477 0.15
B6(AU)-Tubtub/J m 27.7 14.0   26 2.75 0.506 4.0, 54.5 -0.01
B6.BKS(D)-Leprdb/J m 46.6 26.5   15 6.84 0.569 2.8, 95.5 1.17
B6.Cg-Ay/J f 24.2 8.93   22 1.9 0.368 3.3, 39.2 0.6
B6.Cg-Ay/J m 27.2 9.25   31 1.66 0.341 11.7, 49.6 -0.04
B6.Cg-Lepob/J f 32.2 21.7   16 5.43 0.675 9.2, 88.4 1.52
B6.Cg-Lepob/J m 55.0 24.4   18 5.74 0.443 3.4, 93.5 1.69
BKS.Cg-Dock7m +/+ Leprdb/J f 15.0 9.89   9 3.3 0.658 3.5, 32.8 -0.45
BKS.Cg-Dock7m +/+ Leprdb/J m 14.1 8.02   11 2.42 0.567 0.9, 25.1 -0.86
BKSChpLt.HRS-Cpefat/J f 9.93 7.65   16 1.91 0.771 1.1, 26.3 -1.04
BKSChpLt.HRS-Cpefat/J m 13.8 11.5   18 2.71 0.831 2.3, 39.9 -0.88
C57BL/6J f 23.6 7.96   20 1.78 0.338 13.0, 40.6 0.53
C57BL/6J m 28.7 11.0   16 2.75 0.383 10.1, 45.5 0.05
C57BLKS/J f 7.45 2.35   15 0.606 0.315 2.8, 11.4 -1.32
C57BLKS/J m 10.1 4.4   12 1.27 0.435 0.3, 14.5 -1.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J f 20.3238 2.6916 25.6264 15.0213
B6(AU)-Tubtub/J m 27.7192 2.419 32.4847 22.9537
B6.Cg-Ay/J f 24.2318 2.6297 29.4125 19.0512
B6.Cg-Ay/J m 27.1548 2.2154 31.5191 22.7905
B6.Cg-Lepob/J f 32.1812 3.0836 38.2561 26.1064
B6.Cg-Lepob/J m 54.95 2.9073 60.6774 49.2226
BKS.Cg-Dock7m +/+ Leprdb/J f 15.0222 4.1115 23.122 6.9224
BKS.Cg-Dock7m +/+ Leprdb/J m 14.1273 3.719 21.4538 6.8007
BKSChpLt.HRS-Cpefat/J f 9.9313 3.0836 16.0061 3.8564
BKSChpLt.HRS-Cpefat/J m 13.8389 2.9073 19.5663 8.1115
C57BL/6J f 23.595 2.7581 29.0285 18.1615
C57BL/6J m 28.7062 3.0836 34.7811 22.6314
C57BLKS/J f 7.4533 3.1848 13.7274 1.1793
C57BLKS/J m 10.1083 3.5607 17.123 3.0937


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J both 24.0215 1.8094 27.5862 20.4569
B6.Cg-Ay/J both 25.6933 1.7193 29.0803 22.3064
B6.Cg-Lepob/J both 43.5656 2.119 47.7402 39.3911
BKS.Cg-Dock7m +/+ Leprdb/J both 14.5747 2.772 20.0356 9.1139
BKSChpLt.HRS-Cpefat/J both 11.8851 2.119 16.0596 7.7105
C57BL/6J both 26.1506 2.0686 30.2258 22.0755
C57BLKS/J both 8.7808 2.3886 13.4864 4.0753




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA