Project measure / variable:   Paigen3   agLC

ID, description, units MPD:2813   agLC   gallbladder, aggregated liquid crystals (score: 0-4)   [score]  
high-fat diet study
Data set, strains Paigen3   obesity mutants   7 strains     sex: both     age: 15-19wks
Procedure histopathology
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen3 - gallbladder, aggregated liquid crystals (score: 0-4)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means0.853   score 0.706   score
Median of the strain means0.833   score 0.750   score
SD of the strain means± 0.311 ± 0.284
Coefficient of variation (CV)0.365 0.402
Min–max range of strain means0.375   –   1.30   score 0.200   –   1.00   score
Mean sample size per strain7.7   mice 8.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.989 0.989 2.8944 0.0921
strain 6 7.3897 1.2316 3.6044 0.0028
sex:strain 6 1.633 0.2722 0.7965 0.5749
Residuals 98 33.4861 0.3417


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6(AU)-Tubtub/J f 0.833 0.5   9 0.167 0.6 0.5, 2.0 -0.06
B6(AU)-Tubtub/J m 0.944 0.682   9 0.227 0.722 0.84
B6.Cg-Ay/J f 1.1 1.14   5 0.51 1.04 0.8
B6.Cg-Ay/J m 0.65 0.337   10 0.107 0.519 -0.2
B6.Cg-Lepob/J f 1.0 0.577   7 0.218 0.577 0.47
B6.Cg-Lepob/J m 0.75 0.463   8 0.164 0.617 0.15
BKS.Cg-Dock7m +/+ Leprdb/J f 0.611 0.601   9 0.2 0.983 -0.78
BKS.Cg-Dock7m +/+ Leprdb/J m 0.2 0.258   10 0.0816 1.29 -1.78
BKSChpLt.HRS-Cpefat/J f 0.375 0.443   8 0.157 1.18 -1.54
BKSChpLt.HRS-Cpefat/J m 0.5 0.577   10 0.183 1.15 -0.73
C57BL/6J f 1.3 0.789   10 0.249 0.607 0.5, 3.0 1.44
C57BL/6J m 1.0 0.0   6 0.0 0.0 1.0, 1.0 1.03
C57BLKS/J f 0.75 0.689   6 0.281 0.919 -0.33
C57BLKS/J m 0.9 0.742   5 0.332 0.824 0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J f 0.8333 0.1948 1.22 0.4467
B6(AU)-Tubtub/J m 0.9444 0.1948 1.3311 0.5578
B6.Cg-Ay/J f 1.1 0.2614 1.6188 0.5812
B6.Cg-Ay/J m 0.65 0.1848 1.0168 0.2832
B6.Cg-Lepob/J f 1.0 0.2209 1.4384 0.5616
B6.Cg-Lepob/J m 0.75 0.2067 1.1601 0.3399
BKS.Cg-Dock7m +/+ Leprdb/J f 0.6111 0.1948 0.9978 0.2244
BKS.Cg-Dock7m +/+ Leprdb/J m 0.2 0.1848 0.5668 0.0
BKSChpLt.HRS-Cpefat/J f 0.375 0.2067 0.7851 0.0
BKSChpLt.HRS-Cpefat/J m 0.5 0.1848 0.8668 0.1332
C57BL/6J f 1.3 0.1848 1.6668 0.9332
C57BL/6J m 1.0 0.2386 1.4736 0.5264
C57BLKS/J f 0.75 0.2386 1.2236 0.2764
C57BLKS/J m 0.9 0.2614 1.4188 0.3812


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6(AU)-Tubtub/J both 0.8889 0.1378 1.1623 0.6155
B6.Cg-Ay/J both 0.875 0.1601 1.1927 0.5573
B6.Cg-Lepob/J both 0.875 0.1513 1.1752 0.5748
BKS.Cg-Dock7m +/+ Leprdb/J both 0.4056 0.1343 0.6721 0.1391
BKSChpLt.HRS-Cpefat/J both 0.4375 0.1386 0.7126 0.1624
C57BL/6J both 1.15 0.1509 1.4495 0.8505
C57BLKS/J both 0.825 0.177 1.1762 0.4738




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA