Intervention:   methacholine          

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg) Year
Ackerman1 15601 ventilator methacholine individual pulmonary resistance values, a percentage of baseline for the 100 µg/kg dose   [%]  RL100 QTL population f 7-8wks N=372 2005
Ackerman1 15602 ventilator methacholine individual pulmonary resistance, a percentage of baseline for the 330 µg/kg dose   [%]  RL330 QTL population f 7-8wks N=372 2005
Ackerman1 15603 ventilator methacholine individual pulmonary resistance, a percentage of baseline for the 1000 µg/kg dose   [%]  RL1000 QTL population f 7-8wks N=372 2005
Ackerman1 15604 ventilator methacholine individual pulmonary resistance, a percentage of baseline for the 3300 µg/kg dose   [%]  RL3300 QTL population f 7-8wks N=372 2005
Ackerman1 15605 ventilator methacholine effective doses of methacholine required for a 1.50-fold increase in RL), log transformed   [log(n)]  logED150 QTL population f 7-8wks N=372 2005
    Berndt1 34210 ventilator methacholine airway resistance (H2O pressure)   [cm/mL/s]     baseline    MCh challenge (mg/mL):    1    3    10    30 inbred 36 both 9-12wks N=9 2010
    Berndt1 34221 ventilator methacholine airway resistance (as % of baseline, H2O pressure)   [%]     MCh challenge (mg/mL):    1    3    10    30 inbred 36 both 9-12wks N=8 2010
    Berndt2 35101 plethysmography methacholine minute ventilation   [mL/min]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35108 plethysmography methacholine breath frequency   [n/min]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35114 plethysmography methacholine inspiratory phase   [s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35121 plethysmography methacholine expiratory phase   [s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35128 plethysmography methacholine respiratory cycle   [s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35134 plethysmography methacholine duty cycle   [ratio]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35141 plethysmography methacholine inspiratory flow rate   [mL/kg/s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35148 plethysmography methacholine expiratory flow rate   [mL/kg/s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35154 plethysmography methacholine respiratory flow rate   [mL/kg/s]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35161 plethysmography methacholine enhanced pause     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35168 plethysmography methacholine tidal volume   [mL]     saline    5 MCh    10 MCh    20 MCh    response index inbred 29 both 9-12wks N=8 2010
    Berndt2 35181 ventilator methacholine airway resistance (H20 pressure)   [cm/mL/s]     saline    1 MCh    3 MCh    10 MCh    30 MCh    response index inbred 29 both 9-12wks N=9 2010
    Berndt2 35191 ventilator methacholine lung tissue dynamic elastance (H20 pressure)   [cm/mL]     saline    1 MCh    3 MCh    10 MCh    30 MCh    response index inbred 29 both 9-12wks N=9 2010
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Other available data sets:
Data set Procedure What's in this data set Panel Sex Age (weeks) Year
Schwartz4 study archive Lung, respiratory response to ozone. Methacholine-sensitized. None MCh inbred  (8) both 2004