Studies associated with ontology term
VT:0010488   'response to addictive substance trait'
   
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Data set Procedure What's in this data set Panel Sex Age (weeks) Year
Bubier3 monitoring system
with morphine
Induced respiratory depression, time to recovery (for mice that survived), survival data (for mice that did not survive). inbred w/CC8   (8) both 8-24wks 2020
Chesler6 study archive
with ethanol
Sensitivity to ethanol. Baseline and ethanol. QTL population both 9-34wks 2012
Crabbe1 balance beam
with ethanol
Ethanol i.p. (several doses) vs. control (saline). Missteps count. 3 beam lengths. inbred   (8) both 8wks 2003
Crabbe1 grid test
with ethanol
Ethanol injection (several doses) vs. control (saline). Grid habituation, missteps rate. inbred   (8) both 8wks 2003
Crabbe3 rotarod
with ethanol
Baseline and ethanol i.p. 3 fixed speeds (several doses) and accelerating. inbred   (22) both 9-17wks 2003
Crabbe4 dowel balance test
with ethanol
Latency to fall 0 min and 30 min post-injection, 2 widths. Ethanol 2 g/kg. inbred   (21) both 9-17wks 2003
Crabbe4 vertical wire mesh
with ethanol
Latency to fall 30 min post-injection. Ethanol 2 g/kg i.p. inbred   (21) both 9-17wks 2003
Crabbe4 grip strength
with ethanol
Baseline vs. 30 min after ethanol 2 g/kg i.p. inbred   (21) both 9-17wks 2003
Crabbe5 parallel rod floor test
with ethanol
Parallel rod balance test, baseline vs. ethanol 2 g/kg i.p.. inbred   (8) both 7-14wks 2005
CSNA02 bottle choice test Palatable food consumption, preference for Boost solution. CC w/par   (18) both 10-39wks 2023
CSNA03 open field test
with cocaine
Distance traveled, habituation ratio, number of rears, ambulatory time, time in perimeter, corners, and center; cocaine sensitization. CC w/CC8   (61) both 4-25wks 2021
CSNA03 operant conditioning chamber
with cocaine
Number of infusions, active lever presses, inactive lever presses, intravenous self administration, reversal learning. CC w/CC8   (61) both 4-25wks 2021
Finn1 bottle choice test
with ethanol
Voluntary consumption of ethanol, and ethanol with saccharin (several doses in water). inbred   (22) both 8-12wks 2007
Gould2 drug and metabolite quantification
with nicotine
Amount of nicotine and cotinine in blood plasma after nicotine doses. High and lower doses. inbred   (8) m 8-12wks 2011
Gould2 behavior observation
with nicotine
Observed measures of anxiety. Nicotine (high dose) vs. control. 20 min period. inbred   (8) m 8-12wks 2011
Gould2 elevated plus maze
with nicotine
Measures of anxiety. Nicotine (high dose) vs. control. 5 min test. inbred   (8) m 8-12wks 2011
Gould2 fear conditioning test
with nicotine
Contextual fear, cued fear. Nicotine (high and several lower doses) vs. control. inbred   (8) m 8-12wks 2011
Gould3 behavior observation
with nicotine
Observed measures of anxiety during nicotine withdrawal. Nicotine (several high doses) vs. control. inbred   (8) m 8-12wks 2011
Gould3 elevated plus maze
with nicotine
Measures of anxiety during nicotine withdrawal. Nicotine (several high doses) vs. control. inbred   (8) m 8-12wks 2011
Gould3 fear conditioning test
with nicotine
Contextual fear, cued fear during nicotine withdrawal. Nicotine (high and several lower doses) vs. control. inbred   (8) m 8-12wks 2011
Gould4 conditioned place preference test
with nicotine
Nicotine preference and learning effect. Nicotine-treated vs. control. 2 trials (day 5, day 10). inbred   (8) m 8-10wks 2014
Jentsch2 operant conditioning chamber
with cocaine
Intravenous self-administration of cocaine via activation of levers, and locomotor activity. BXD   (4) both 8-17wks 2013
Kumar1 study archive
with cocaine
Open field test. Locomotor, anxiety-related, circadian behavior. Baseline and after cocaine i.p. QTL population both 10-14wks 2014
Metten1 behavior observation
with ethanol
Observed gait, hindlimb splay 10 min and 30 min after ethanol i.p. (several doses). inbred   (9) both 8-11wks 2004
Metten1 open field test
with ethanol
Locomotor activity. Ethanol i.p. (several doses) vs. control (saline i.p.). 45s test. inbred   (9) both 8-11wks 2004
Metten2 behavior observation
with ethanol
Ethanol withdrawal severity and handling-induced convulsions. inbred   (15) m 8-11wks 2005
Palmer2 open field test
with methamphetamine
Locomotor activity and habituation. Baseline (saline) vs. methamphetamine 2 mg/kg i.p. 30 min test. B6.A consomic w/par   (21) both 10wks 2008
Rusyn5 metabolic panel
with high-fat diet and ethanol
Alanine transaminase (serum) after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 alcohol quantification
with high-fat diet and ethanol
Alcohol concentration in blood and urine after 4 wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 organ weights
with high-fat diet and ethanol
Liver weight after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 histopathology
with high-fat diet and ethanol
Liver histopathology, injury after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 metabolite quantification
with high-fat diet and ethanol
Homocysteine concentration after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 lipid profile
with high-fat diet and ethanol
Hepatic triglycerides after 4wk regimen of ethanol and high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 RNA expression profiling
with high-fat diet and ethanol
Liver gene expression after 4wk regimen of ethanol and high-fat diet. 24h fast. mRNA abundance relative to the control (high-fat only) group. inbred   (14) m 8-14wks 2011
Tarantino1 open field test
with cocaine
Locomotor activity. Baseline (saline) vs. cocaine 20 mg/kg i.p. 30 min test. inbred   (45) m 8-11wks 2015
Thomsen1 open field test
with cocaine
Locomotor activity. Baseline (saline) vs. cocaine i.p. (several doses). 1.3h and 2.3 h duration. inbred   (15) both 8-10wks 2011