Project measure / variable:   GMC01   center_time_total

ID, description, units MPD:55065   center_time_total   percentage of total time spent in center, 20 min test   [%]  
Data set, strains GMC01   inbred w/CC8   8 strains     sex: both     age: 8-9wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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GMC01 - percentage of total time spent in center, 20 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means11.7   % 10.7   %
Median of the strain means12.7   % 11.8   %
SD of the strain means± 9.82 ± 8.25
Coefficient of variation (CV)0.842 0.773
Min–max range of strain means0.106   –   30.5   % 0.175   –   23.4   %
Mean sample size per strain17.5   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 102.2582 102.2582 5.684 0.0178
strain 7 18724.2961 2674.8994 148.6848 < 0.0001
sex:strain 7 471.0995 67.2999 3.7409 0.0007
Residuals 259 4659.5151 17.9904


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.11 2.86   16 0.714 1.35 -0.97
129S1/SvImJ m 0.673 0.822   15 0.212 1.22 -1.21
A/J f 0.106 0.257   16 0.0642 2.42 -1.18
A/J m 0.175 0.442   16 0.11 2.53 -1.27
C57BL/6J f 16.3 4.79   16 1.2 0.294 10.2, 26.0 0.47
C57BL/6J m 17.4 3.59   16 0.897 0.206 12.5, 28.0 0.82
CAST/EiJ f 13.6 2.92   19 0.671 0.215 7.0, 19.0 0.2
CAST/EiJ m 15.2 4.58   18 1.08 0.303 6.8, 23.1 0.55
NOD/ShiLtJ f 30.5 8.14   18 1.92 0.267 18.9, 47.4 1.92
NOD/ShiLtJ m 23.4 4.02   16 1.01 0.172 16.5, 29.7 1.54
NZO/HlLtJ f 3.94 5.49   17 1.33 1.4 -0.79
NZO/HlLtJ m 4.91 4.64   17 1.13 0.946 0.1, 17.3 -0.7
PWK/PhJ f 11.8 3.03   20 0.678 0.257 7.3, 17.8 0.01
PWK/PhJ m 10.6 2.73   22 0.581 0.257 6.2, 14.3 -0.01
WSB/EiJ f 14.9 3.34   18 0.788 0.224 7.6, 23.1 0.33
WSB/EiJ m 13.0 7.35   15 1.9 0.564 5.7, 28.9 0.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.1125 1.0604 4.2006 0.0244
129S1/SvImJ m 0.6733 1.0952 2.8299 -1.4832
A/J f 0.1062 1.0604 2.1943 -1.9818
A/J m 0.175 1.0604 2.2631 -1.9131
C57BL/6J f 16.2625 1.0604 18.3506 14.1744
C57BL/6J m 17.45 1.0604 19.5381 15.3619
CAST/EiJ f 13.6105 0.9731 15.5267 11.6944
CAST/EiJ m 15.1556 0.9997 17.1242 13.1869
NOD/ShiLtJ f 30.5333 0.9997 32.502 28.5647
NOD/ShiLtJ m 23.3625 1.0604 25.4506 21.2744
NZO/HlLtJ f 3.9353 1.0287 5.961 1.9096
NZO/HlLtJ m 4.9059 1.0287 6.9316 2.8802
PWK/PhJ f 11.79 0.9484 13.6576 9.9224
PWK/PhJ m 10.5909 0.9043 12.3716 8.8102
WSB/EiJ f 14.9222 0.9997 16.8909 12.9536
WSB/EiJ m 13.04 1.0952 15.1965 10.8835


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.3929 0.7622 2.8938 -0.108
A/J both 0.1406 0.7498 1.6171 -1.3359
C57BL/6J both 16.8563 0.7498 18.3327 15.3798
CAST/EiJ both 14.383 0.6976 15.7566 13.0094
NOD/ShiLtJ both 26.9479 0.7287 28.3828 25.513
NZO/HlLtJ both 4.4206 0.7274 5.853 2.9882
PWK/PhJ both 11.1905 0.6552 12.4807 9.9002
WSB/EiJ both 13.9811 0.7414 15.4411 12.5211




  GWAS USING LINEAR MIXED MODELS