Project measure / variable:   GMC01   center_distance_total

ID, description, units MPD:55055   center_distance_total   percentage of total distance in center, 20 min test   [%]  
Data set, strains GMC01   inbred w/CC8   8 strains     sex: both     age: 8-9wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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GMC01 - percentage of total distance in center, 20 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means17.7   % 16.0   %
Median of the strain means20.8   % 19.6   %
SD of the strain means± 13.0 ± 11.4
Coefficient of variation (CV)0.735 0.708
Min–max range of strain means0.337   –   37.4   % 0.194   –   29.4   %
Mean sample size per strain17.5   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 278.4916 278.4916 13.4583 0.0003
strain 7 34094.1427 4870.5918 235.3755 < 0.0001
sex:strain 7 507.2764 72.4681 3.5021 0.0013
Residuals 259 5359.4509 20.6929


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.42 4.07   16 1.02 0.921 -1.02
129S1/SvImJ m 1.82 2.08   15 0.536 1.14 -1.25
A/J f 0.337 0.65   16 0.163 1.93 -1.34
A/J m 0.194 0.431   16 0.108 2.23 -1.39
C57BL/6J f 25.2 5.11   16 1.28 0.203 17.5, 34.8 0.57
C57BL/6J m 24.4 3.93   16 0.982 0.161 19.1, 32.2 0.74
CAST/EiJ f 25.7 3.42   19 0.785 0.133 18.8, 30.4 0.61
CAST/EiJ m 25.2 4.81   18 1.13 0.191 15.4, 33.7 0.81
NOD/ShiLtJ f 37.4 5.2   18 1.23 0.139 29.5, 47.0 1.51
NOD/ShiLtJ m 29.4 4.83   16 1.21 0.165 21.7, 37.4 1.18
NZO/HlLtJ f 6.31 7.02   17 1.7 1.11 -0.88
NZO/HlLtJ m 8.12 6.61   17 1.6 0.814 0.3, 20.9 -0.7
PWK/PhJ f 16.4 3.89   20 0.87 0.237 10.3, 22.7 -0.1
PWK/PhJ m 15.7 3.0   22 0.64 0.191 10.2, 20.6 -0.03
WSB/EiJ f 26.0 4.44   18 1.05 0.171 15.0, 35.8 0.64
WSB/EiJ m 23.5 7.09   15 1.83 0.302 14.8, 38.9 0.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.4187 1.1372 6.6582 2.1793
129S1/SvImJ m 1.82 1.1745 4.1328 -0.4928
A/J f 0.3375 1.1372 2.5769 -1.9019
A/J m 0.1937 1.1372 2.4332 -2.0457
C57BL/6J f 25.1687 1.1372 27.4082 22.9293
C57BL/6J m 24.4312 1.1372 26.6707 22.1918
CAST/EiJ f 25.6789 1.0436 27.734 23.6239
CAST/EiJ m 25.2111 1.0722 27.3224 23.0998
NOD/ShiLtJ f 37.3944 1.0722 39.5058 35.2831
NOD/ShiLtJ m 29.3687 1.1372 31.6082 27.1293
NZO/HlLtJ f 6.3059 1.1033 8.4784 4.1333
NZO/HlLtJ m 8.1235 1.1033 10.2961 5.951
PWK/PhJ f 16.435 1.0172 18.438 14.432
PWK/PhJ m 15.7364 0.9698 17.6461 13.8266
WSB/EiJ f 26.0 1.0722 28.1113 23.8887
WSB/EiJ m 23.4533 1.1745 25.7662 21.1405


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.1194 0.8174 4.729 1.5097
A/J both 0.2656 0.8041 1.8491 -1.3179
C57BL/6J both 24.8 0.8041 26.3835 23.2165
CAST/EiJ both 25.445 0.7481 26.9182 23.9719
NOD/ShiLtJ both 33.3816 0.7815 34.9205 31.8427
NZO/HlLtJ both 7.2147 0.7801 8.7509 5.6785
PWK/PhJ both 16.0857 0.7027 17.4694 14.7019
WSB/EiJ both 24.7267 0.7952 26.2925 23.1609




  GWAS USING LINEAR MIXED MODELS