Project measure / variable:   GMC01   whole_speed

ID, description, units MPD:55032   whole_speed   average speed in whole arena, 20 min test   [cm/s]  
Data set, strains GMC01   inbred w/CC8   8 strains     sex: both     age: 8-9wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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GMC01 - average speed in whole arena, 20 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means16.1   cm/s 15.0   cm/s
Median of the strain means14.4   cm/s 13.6   cm/s
SD of the strain means± 11.3 ± 10.2
Coefficient of variation (CV)0.699 0.681
Min–max range of strain means2.38   –   35.3   cm/s 3.74   –   32.9   cm/s
Mean sample size per strain17.5   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 142.56 142.56 9.3013 0.0025
strain 7 26881.3855 3840.1979 250.5532 < 0.0001
sex:strain 7 126.3981 18.0569 1.1781 0.3156
Residuals 259 3969.6606 15.3269


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.06 7.8   16 1.95 1.1 1.5, 35.0 -0.8
129S1/SvImJ m 6.51 1.44   15 0.372 0.221 3.6, 9.0 -0.83
A/J f 2.38 1.13   16 0.283 0.477 0.9, 4.3 -1.22
A/J m 3.74 3.15   16 0.789 0.844 1.9, 15.1 -1.1
C57BL/6J f 26.0 3.82   16 0.956 0.147 18.3, 31.7 0.87
C57BL/6J m 25.0 4.63   16 1.16 0.185 19.2, 37.8 0.97
CAST/EiJ f 15.2 2.51   19 0.577 0.165 10.2, 20.2 -0.08
CAST/EiJ m 13.9 2.54   18 0.6 0.183 11.1, 19.1 -0.11
NOD/ShiLtJ f 35.3 6.73   18 1.59 0.19 22.7, 46.8 1.7
NOD/ShiLtJ m 32.9 4.89   16 1.22 0.148 23.4, 40.7 1.74
NZO/HlLtJ f 6.23 2.31   17 0.561 0.372 3.9, 11.7 -0.88
NZO/HlLtJ m 5.48 1.89   17 0.459 0.346 3.3, 10.6 -0.93
PWK/PhJ f 13.7 2.63   20 0.589 0.192 10.0, 19.9 -0.22
PWK/PhJ m 13.3 2.65   22 0.564 0.199 8.8, 19.1 -0.17
WSB/EiJ f 23.2 4.57   18 1.08 0.197 14.6, 31.6 0.63
WSB/EiJ m 19.5 3.69   15 0.953 0.189 13.3, 27.5 0.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.0625 0.9787 8.9898 5.1352
129S1/SvImJ m 6.5067 1.0108 8.4972 4.5162
A/J f 2.375 0.9787 4.3023 0.4477
A/J m 3.7375 0.9787 5.6648 1.8102
C57BL/6J f 25.9563 0.9787 27.8835 24.029
C57BL/6J m 25.0313 0.9787 26.9585 23.104
CAST/EiJ f 15.2368 0.8982 17.0055 13.4682
CAST/EiJ m 13.8667 0.9228 15.6837 12.0496
NOD/ShiLtJ f 35.3333 0.9228 37.1504 33.5163
NOD/ShiLtJ m 32.925 0.9787 34.8523 30.9977
NZO/HlLtJ f 6.2294 0.9495 8.0992 4.3597
NZO/HlLtJ m 5.4765 0.9495 7.3462 3.6067
PWK/PhJ f 13.72 0.8754 15.4438 11.9962
PWK/PhJ m 13.3227 0.8347 14.9663 11.6791
WSB/EiJ f 23.1889 0.9228 25.006 21.3718
WSB/EiJ m 19.52 1.0108 21.5105 17.5295


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 6.7846 0.7035 8.1699 5.3993
A/J both 3.0562 0.6921 4.4191 1.6934
C57BL/6J both 25.4938 0.6921 26.8566 24.1309
CAST/EiJ both 14.5518 0.6438 15.8196 13.2839
NOD/ShiLtJ both 34.1292 0.6726 35.4536 32.8048
NZO/HlLtJ both 5.8529 0.6714 7.1751 4.5308
PWK/PhJ both 13.5214 0.6048 14.7123 12.3305
WSB/EiJ both 21.3544 0.6843 22.702 20.0069




  GWAS USING LINEAR MIXED MODELS