Project measure / variable:   GMC01   center_speed

ID, description, units MPD:55044   center_speed   average speed in center of arena, 20 min test   [cm/s]  
Data set, strains GMC01   inbred w/CC8   8 strains     sex: both     age: 8-9wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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GMC01 - average speed in center of arena, 20 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means24.8   cm/s 23.1   cm/s
Median of the strain means22.8   cm/s 20.2   cm/s
SD of the strain means± 14.0 ± 12.1
Coefficient of variation (CV)0.562 0.525
Min–max range of strain means3.16   –   42.4   cm/s 5.81   –   39.7   cm/s
Mean sample size per strain17.5   mice 16.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 340.2297 340.2297 3.961 0.0476
strain 7 39341.9077 5620.2725 65.4313 < 0.0001
sex:strain 7 384.9284 54.9898 0.6402 0.7224
Residuals 258 22161.1255 85.8958


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 19.7 17.3   16 4.33 0.88 -0.37
129S1/SvImJ m 18.6 16.2   14 4.32 0.871 -0.37
A/J f 3.16 5.96   16 1.49 1.88 -1.55
A/J m 5.81 13.3   16 3.32 2.29 -1.42
C57BL/6J f 39.3 5.76   16 1.44 0.146 30.5, 50.9 1.04
C57BL/6J m 34.4 5.75   16 1.44 0.167 25.8, 46.9 0.93
CAST/EiJ f 25.9 7.47   19 1.71 0.289 16.5, 44.1 0.08
CAST/EiJ m 21.8 5.35   18 1.26 0.245 15.0, 32.8 -0.11
NOD/ShiLtJ f 42.4 10.6   18 2.5 0.25 19.0, 58.6 1.26
NOD/ShiLtJ m 39.7 6.71   16 1.68 0.169 29.4, 50.1 1.37
NZO/HlLtJ f 13.2 14.5   17 3.53 1.1 -0.83
NZO/HlLtJ m 10.9 4.13   17 1.0 0.378 4.1, 17.1 -1.01
PWK/PhJ f 17.6 3.69   20 0.825 0.21 12.9, 28.1 -0.52
PWK/PhJ m 18.7 3.53   22 0.753 0.189 11.1, 26.7 -0.36
WSB/EiJ f 37.5 8.24   18 1.94 0.22 15.1, 49.6 0.91
WSB/EiJ m 34.9 6.96   15 1.8 0.199 23.8, 49.8 0.97


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 19.7 2.317 24.2626 15.1374
129S1/SvImJ m 18.5714 2.477 23.4491 13.6938
A/J f 3.1625 2.317 7.7251 -1.4001
A/J m 5.8125 2.317 10.3751 1.2499
C57BL/6J f 39.3437 2.317 43.9064 34.7811
C57BL/6J m 34.4312 2.317 38.9939 29.8686
CAST/EiJ f 25.8526 2.1262 30.0396 21.6657
CAST/EiJ m 21.8444 2.1845 26.1461 17.5427
NOD/ShiLtJ f 42.4222 2.1845 46.7239 38.1205
NOD/ShiLtJ m 39.725 2.317 44.2876 35.1624
NZO/HlLtJ f 13.2294 2.2478 17.6558 8.803
NZO/HlLtJ m 10.9235 2.2478 15.3499 6.4971
PWK/PhJ f 17.595 2.0724 21.6759 13.5141
PWK/PhJ m 18.6818 1.9759 22.5729 14.7908
WSB/EiJ f 37.5111 2.1845 41.8128 33.2094
WSB/EiJ m 34.9267 2.393 39.6389 30.2144


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 19.1357 1.6959 22.4752 15.7962
A/J both 4.4875 1.6384 7.7138 1.2612
C57BL/6J both 36.8875 1.6384 40.1138 33.6612
CAST/EiJ both 23.8485 1.5242 26.85 20.8471
NOD/ShiLtJ both 41.0736 1.5922 44.209 37.9382
NZO/HlLtJ both 12.0765 1.5894 15.2064 8.9465
PWK/PhJ both 18.1384 1.4317 20.9577 15.3191
WSB/EiJ both 36.2189 1.6201 39.4091 33.0287




  GWAS USING LINEAR MIXED MODELS