Studies associated with ontology term
MA:0000324   'hepatobiliary system'
   
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Data set Procedure What's in this data set Panel Sex Age (weeks) Year
Ankra-Badu1 study archive Body, organ, fat pad weights, weight gain, litter size. QTL population both 2-10wks 2009
Attie2 organ weights
with high-fat high-sucrose diet
Heart, liver, gonadal fat pads. DO population both 4-26wks 2018
Auwerx1 organ weights
with high-fat diet
Skeletal muscle, soleus muscle, heart, kidney, liver, various fat pads. BXD w/par   (57) m 8-29 wks 2016
Auwerx2 organ weights
with high-fat diet
Cecum, muscles, heart, heart-atria, kidney, liver, spleen, fat pads. inbred w/CC8 both 8-21 wks 2021
Bopp1 health assessment
with Plasmodium berghei
Susceptibility, Plasmodium berghei (malaria). Parasitemia in blood and distribution in brain, spleen, lungs, liver. inbred   (31) both 8-12wks 2010
Brockmann1 study archive Body, organ weights, litter size, abdominal fat, lipids, insulin, leptin. QTL population both 3-6wks 2009
Cheverud1 organ weights
with high-fat diet
Heart, liver, kidney, spleen weights after high-fat diet (17wks) vs. control. LGXSM w/par   (19) both 12-16wks 2004
GMC21 organ weights Heart, liver, spleen weights. inbred w/CC8   (8) both 20-21wks 2020
Harrill1 organ weights
with isoniazid
Body, liver, kidney weights. Isoniazid-treated vs. control. inbred   (34) f 8-10wks 2011
Harrill1 lipid profile
with isoniazid
Cholesterol, triglycerides. Hepatic lipids. Isoniazid-treated vs. control. inbred   (34) f 8-10wks 2011
Harrill1 histopathology
with isoniazid
Liver pathology scores. Isoniazid-treated vs. control. inbred   (34) f 8-10wks 2011
Harrill2 organ weights
with DB289
Kidney and liver weights. DB289-treated vs. control. inbred   (34) f 6-8wks 2012
Ishimori1 study archive
with high-fat diet
Lipids, atherosclerosis lesions, parathyroid hormone after high-fat diet. QTL population f 20wks 2004
Jaxpheno2 organ weights Brain, heart, kidney, liver, spleen weights. inbred   (11) both 8, 16 wks 2006
Klaassen1 histopathology
with cadmium
Cadmium-induced toxicity to liver, testis, trigeminal ganglia. inbred   (8) m 8wks 2001
Lyons1 study archive
with high-fat diet
Lipids (plasma), liver weight, gallbladder and gallstone histopathology. QTL population m 16-18wks 2003
Lyons2 study archive
with high-fat diet
Lipids (plasma), bile, liver weight, gallbladder and gallstone histopathology. QTL population m 16-18wks 2003
Lyons3 study archive
with high-fat diet
Lipids, gallbladder and gallstone histopathology after high-fat diet. QTL population m 14-20wks 2004
Lyons4 study archive
with high-fat diet
Gallstone susceptibility. QTL population both 24-26wks 2005
Mrug1 study archive Kidney morphology. QTL population both 1-2wks 2005
Nadeau2 lipid profile
with high-fat high-sucrose diet
Cholesterol, triglycerides. 16h fast, plasma. Hepatic triglycerides. B6.A consomic w/par   (24) m 5, 21 wks 2015
Nadeau2 organ weights
with high-fat high-sucrose diet
Liver weight after 16wks of high-fat high-sucrose diet. 16h fast. B6.A consomic w/par   (24) m 5, 21 wks 2015
Nadeau3 lipid profile
with high-fat high-sucrose diet
Cholesterol and triglycerides. Overnight fast, plasma. Hepatic triglycerides. inbred   (2) m 21 wks 2016
Nadeau3 organ weights
with high-fat high-sucrose diet
Liver weight after 16 wks of high-fat high-sucrose diet. Overnight fast. inbred   (2) m 21 wks 2016
Paigen1 lipid profile
with high-fat diet
Cholesterol, HDL, non-HDL. 4h fast, plasma. Hepatic lipids. 8wks on high-fat diet. inbred   (44) both 15-19wks 2000
Paigen1 histopathology
with high-fat diet
Gallstone, gallbladder, and atherosclerosis lesion histopathology after 8wks on high-fat diet. inbred   (44) both 15-19wks 2000
Paigen1 organ dimensions
with high-fat diet
Gallbladder volume after 8wks on high-fat diet. inbred   (44) both 15-19wks 2000
Paigen1 organ weights
with high-fat diet
Liver weight after 8wks on high-fat diet. inbred   (44) both 15-19wks 2000
Paigen3 lipid profile
with high-fat diet
Cholesterol, HDL, non-HDL. 4h fast, plasma. Hepatic lipids. 8wks on high-fat diet. obesity mutants   (8) both 15-19wks 2000
Paigen3 histopathology
with high-fat diet
Gallstone, gallbladder, and atherosclerosis lesion histopathology after 8wks on high-fat diet obesity mutants   (8) both 15-19wks 2000
Paigen3 organ dimensions
with high-fat diet
Gallbladder volume after 8wks on high-fat diet obesity mutants   (8) both 15-19wks 2000
Paigen3 organ weights
with high-fat diet
Liver weight after 8wks on high-fat diet. obesity mutants   (8) both 15-19wks 2000
Reed2 organ weights Brain, heart, kidney, liver, pancreas, spleen weights. B6.129 and 129.B6 consomic w/par   (9) both 26wks 2015
Rodriguez1 study archive Spleen, liver murine cytomegalovirus study. QTL population both 8-12wks 2009
Rusyn5 organ weights
with high-fat diet and ethanol
Liver weight after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 histopathology
with high-fat diet and ethanol
Liver histopathology, injury after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 metabolite quantification
with high-fat diet and ethanol
Homocysteine concentration after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 lipid profile
with high-fat diet and ethanol
Hepatic triglycerides after 4wk regimen of ethanol and high-fat diet. 24h fast. inbred   (14) m 8-14wks 2011
Rusyn5 RNA expression profiling
with high-fat diet and ethanol
Liver gene expression after 4wk regimen of ethanol and high-fat diet. 24h fast. mRNA abundance relative to the control (high-fat only) group. inbred   (14) m 8-14wks 2011
Rusyn6 organ weights
with trichloroethylene
Liver, kidney weights. Trichloroethylene-exposed vs. control. inbred   (7) m 6-7wks 2014
Rusyn6 drug and metabolite quantification
with trichloroethylene
Trichloroethylene metabolite in blood, liver, kidney after trichloroethylene exposure. inbred   (7) m 6-7wks 2014
Rusyn6 RNA expression profiling
with trichloroethylene
Trichloroethylene effect on mRNA gene expression in liver and kidney, relative to controls. inbred   (7) m 6-7wks 2014
Rusyn6 histopathology
with trichloroethylene
Kidney histopathology evaluation after trichloroethylene exposure, relative to controls. inbred   (7) m 6-7wks 2014
Schonfeld1 lipid profile Cholesterol, triglycerides, free fatty acids, phospholipids. 5h fast, plasma. Hepatic triglycerides. inbred   (11) both 8-10wks 2005
Schonfeld1 organ weights Liver weight. inbred   (11) both 8-10wks 2005
Schoonjans1 biomarker quantification
with high-fat diet
Bile acid levels in plasma, feces, and liver. BXD w/par   (36) m 8-29 wks 2022
Schoonjans1 organ weights
with high-fat diet
Liver, spleen, kidney, fat pads, muscles, cecum. BXD w/par   (36) m 8-29 wks 2022
Sunde1 RNA expression profiling
with selenium
Selenium regulation of selenoprotein enzyme activity and transcripts. inbred w/CC8   (8) m 3-14wks 2018
Threadgill1 metabolic panel
with acetaminophen
Blood urea nitrogen, alanine transaminase, aspartate transaminase (serum), liver enzyme homeostasis. Acetaminophen (several doses) vs. control, several timepoints post-Rx. 18h fast. inbred w/CC7   (37) m 8-17wks 2005
Threadgill1 histopathology
with acetaminophen
Liver histopathology, necrosis after acetaminophen vs. control. 18h fast. inbred w/CC7   (37) m 8-17wks 2005
Threadgill1 metabolite quantification
with acetaminophen
Liver protein homeostasis. Acetaminophen vs. control. 18h fast. inbred w/CC7   (37) m 8-17wks 2005
Threadgill1 biomarker quantification
with acetaminophen
Liver cytochrome isoforms. Acetaminophen vs. control. 18h fast. inbred w/CC7   (37) m 8-17wks 2005
Threadgill1 organ weights
with acetaminophen
Liver weight after acetaminophen (several doses) vs. control. 18h fast. inbred w/CC7   (37) m 8-17wks 2005
Threadgill2 metabolite quantification
with acetaminophen
Glutathione. inbred   (5) m 6-8wks 2005
Threadgill2 histopathology
with acetaminophen
Liver histopathology, necrosis, injury after acetaminophen vs. control. 18h fast. inbred   (5) m 6-8wks 2005
Vulpe1 mineral quantification Liver mineral levels. Iron, copper, zinc. Iron homeostasis. inbred   (18) both 8wks 2010
Wittenburg1 study archive
with high-fat diet
Liver weight, gallbladder and gallstone histopathology. QTL population both 18-20wks 2002
Wittenburg2 study archive
with high-fat diet
Lipids (plasma), liver weight, gallbladder and gallstone histopathology. QTL population both 6-16wks 2003
Wittenburg3 study archive
with high-fat diet
Lipids (plasma), liver weight, gallbladder and gallstone histopathology. QTL population both 2005
Xenakis2 metabolite quantification
with arsenic
iAs quantification in urine and liver, at 24 and 26 wks after iAs exposure. IAs speciation evaluated specifically monomethyl-arsenic acid (MMA) and dimethyl-arsenic acid (DMA) DO population m 4-34 wks 2022
Yi1 study archive Body weight (several timepoints) and liver weight. QTL population both 2-12wks 2007