Klaassen1: Cadmium toxicity in the testes, liver, and trigeminal ganglia in males of 8 inbred strains of mice (2001)

Habeebu SS, Liu Y, Park JD, Klaassen CD. Strain differences in the toxicity of cadmium to trigeminal ganglia in mice. Toxicol Appl Pharmacol. 2001 Dec 15;177(3):200-7.   PubMed 11749119  


       
Klaassen1 downloads
• Download Klaassen1 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Curtis D Klaassen       University of Kansas Medical Center Kansas City, KS
With: Habeebu SS, Liu Y, Park JD
ContactCurtis D Klaassen     cklaasse@kumc.edu     Lab web site
AcknowledgementsFunding provided by NIH ES01142, ES07079.
Project type Phenotype strain survey data set
MPD identifiersKlaassen1     MPD:164
Data changelog No updates/corrections.       Initial release date: 03/2004.
Formatted citation
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A tissue or organ is resistant to Cd toxicity if there is no biochemical and/or morphological evidence of toxicity despite increasing doses of Cd to the lethal range. Coding: R = resistant; S = sensitive; HS = highly sensitive; 1 = degeneration only; 2 = degeneration, hemorrhage; 3 = degeneration, necrosis; 4 = degeneration, hemorrhage, necrosis

Summary of procedures that were conducted
• histopathology Cadmium-induced toxicity to liver, testis, trigeminal ganglia.
Mice: inbred   8 strains   ♂   age 8wks   2 cohorts

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Klaassen1 16401 histopathology cadmium Cd-induced toxicity to testis   [designation]  testis inbred m 8wks
    Klaassen1 16402 histopathology cadmium Cd-induced toxicity to liver   [designation]  liver inbred m 8wks
    Klaassen1 16403 histopathology cadmium Cd-induced toxicity to trigeminal ganglia   [designation]  ganglia inbred m 8wks
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