Phenotype measure

ID, description, units MPD:27362   CHOL   total cholesterol (plasma CHOL)   [mg/dL]
Data set, strains Svenson3   B6.PWD consomic w/par   28 strains     sex: both     age: 8wks
Procedure lipid profile
Ontology mappings


  STRAIN COMPARISON PLOT
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Svenson3 - total cholesterol (plasma CHOL)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means76.5   mg/dL 93.3   mg/dL
Median of the strain means77.7   mg/dL 95.7   mg/dL
SD of the strain means± 7.96 ± 9.68
Coefficient of variation (CV)0.104 0.104
Min–max range of strain means60.0   –   93.2   mg/dL 73.9   –   110   mg/dL
Mean sample size per strain7.7   mice 8.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 31745.2862 31745.2862 370.4211 < 0.0001
strain 27 28174.3014 1043.4926 12.176 < 0.0001
sex:strain 27 4302.9191 159.3674 1.8596 0.0064
Residuals 391 33508.9072 85.7005


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 75.8 6.98   8 2.47 0.0922 66.0, 87.0 -0.09
B6.PWD-Chr1 m 108.0 10.2   10 3.22 0.0941 94.0, 121.0 1.52
B6.PWD-Chr10.1 f 76.3 5.97   12 1.72 0.0783 67.0, 86.0 -0.03
B6.PWD-Chr10.1 m 83.0 8.43   10 2.67 0.102 69.0, 94.0 -1.07
B6.PWD-Chr10.2 f 74.7 13.4   6 5.48 0.18 60.0, 94.0 -0.23
B6.PWD-Chr10.2 m 83.7 8.5   3 4.91 0.102 75.0, 92.0 -0.99
B6.PWD-Chr10.3 f 67.9 8.48   8 3.0 0.125 57.0, 78.0 -1.08
B6.PWD-Chr10.3 m 78.6 4.03   8 1.43 0.0513 71.0, 83.0 -1.52
B6.PWD-Chr11.1 f 60.0 8.72   3 5.03 0.145 54.0, 70.0 -2.07
B6.PWD-Chr11.1 m 83.0 6.0   3 3.46 0.0723 77.0, 89.0 -1.07
B6.PWD-Chr11.2 f 79.8 8.16   10 2.58 0.102 66.0, 94.0 0.41
B6.PWD-Chr11.2 m 100.0 6.93   10 2.19 0.0691 87.0, 108.0 0.69
B6.PWD-Chr11.3 f 83.8 5.37   8 1.9 0.0641 76.0, 94.0 0.92
B6.PWD-Chr11.3 m 101.0 13.8   8 4.88 0.137 81.0, 120.0 0.79
B6.PWD-Chr12 f 81.3 9.81   9 3.27 0.121 70.0, 101.0 0.6
B6.PWD-Chr12 m 102.0 8.4   10 2.66 0.0822 87.0, 115.0 0.9
B6.PWD-Chr13 f 80.5 10.3   8 3.65 0.128 69.0, 99.0 0.5
B6.PWD-Chr13 m 93.9 11.1   8 3.91 0.118 80.0, 107.0 0.06
B6.PWD-Chr14 f 81.0 8.29   10 2.62 0.102 70.0, 96.0 0.57
B6.PWD-Chr14 m 100.0 6.83   10 2.16 0.0681 85.0, 106.0 0.69
B6.PWD-Chr15 f 83.1 8.59   8 3.04 0.103 66.0, 96.0 0.83
B6.PWD-Chr15 m 96.2 8.58   8 3.03 0.0892 86.0, 111.0 0.3
B6.PWD-Chr16 f 77.9 7.57   8 2.68 0.0972 67.0, 93.0 0.18
B6.PWD-Chr16 m 97.1 9.03   8 3.19 0.093 86.0, 110.0 0.39
B6.PWD-Chr17 f 77.4 11.8   7 4.46 0.152 61.0, 90.0 0.11
B6.PWD-Chr17 m 87.0 13.4   8 4.74 0.154 67.0, 109.0 -0.65
B6.PWD-Chr18 f 67.4 5.68   5 2.54 0.0843 59.0, 72.0 -1.14
B6.PWD-Chr18 m 73.9 6.43   9 2.14 0.087 60.0, 82.0 -2.01
B6.PWD-Chr19 f 93.2 9.38   8 3.32 0.101 85.0, 111.0 2.1
B6.PWD-Chr19 m 110.0 15.7   8 5.54 0.143 75.0, 125.0 1.72
B6.PWD-Chr2 f 68.1 13.4   7 5.08 0.197 51.0, 89.0 -1.05
B6.PWD-Chr2 m 101.0 10.2   10 3.22 0.101 85.0, 114.0 0.79
B6.PWD-Chr3 f 64.6 4.9   8 1.73 0.0758 57.0, 72.0 -1.49
B6.PWD-Chr3 m 77.2 4.99   9 1.66 0.0647 70.0, 83.0 -1.67
B6.PWD-Chr5 f 70.2 7.34   9 2.45 0.105 63.0, 84.0 -0.79
B6.PWD-Chr5 m 87.3 8.15   11 2.46 0.0934 72.0, 99.0 -0.62
B6.PWD-Chr6 f 71.6 11.6   9 3.88 0.163 59.0, 96.0 -0.62
B6.PWD-Chr6 m 89.0 13.7   8 4.84 0.154 63.0, 108.0 -0.45
B6.PWD-Chr8 f 85.3 6.11   3 3.53 0.0716 80.0, 92.0 1.11
B6.PWD-Chr8 m 95.2 6.46   5 2.89 0.0678 88.0, 103.0 0.19
B6.PWD-Chr9 f 69.2 7.77   9 2.59 0.112 56.0, 76.0 -0.92
B6.PWD-Chr9 m 87.9 5.19   8 1.84 0.0591 78.0, 96.0 -0.56
B6.PWD-ChrX.1 f 89.8 5.75   8 2.03 0.0641 80.0, 97.0 1.67
B6.PWD-ChrX.1 m 108.0 10.7   8 3.79 0.0996 93.0, 125.0 1.52
B6.PWD-ChrX.2 f 86.4 11.1   7 4.2 0.128 71.0, 100.0 1.24
B6.PWD-ChrX.2 m 97.9 13.0   10 4.12 0.133 81.0, 129.0 0.47
B6.PWD-ChrX.3 f 68.2 2.36   4 1.18 0.0346 65.0, 70.0 -1.04
B6.PWD-ChrX.3 m 86.2 7.14   4 3.57 0.0827 76.0, 92.0 -0.74
B6.PWD-ChrY f 78.0 8.54   8 3.02 0.109 65.0, 89.0 0.19
B6.PWD-ChrY m 99.3 5.56   7 2.1 0.056 90.0, 106.0 0.62
B6.PWD-mt f 78.0 8.78   8 3.11 0.113 66.0, 87.0 0.19
B6.PWD-mt m 100.0 10.6   8 3.76 0.106 87.0, 117.0 0.69
C57BL/6J f 70.1 8.94   8 3.16 0.127 53.0, 81.0 -0.8
C57BL/6J m 87.2 11.9   12 3.42 0.136 58.0, 102.0 -0.63
PWD/PhJ f 82.4 8.58   10 2.71 0.104 67.0, 94.0 0.74
PWD/PhJ m 99.6 9.2   10 2.91 0.0924 80.0, 112.0 0.65


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 75.75 3.273 82.1849 69.3151
B6.PWD-Chr1 m 108.1 2.9275 113.8555 102.3445
B6.PWD-Chr10.1 f 76.3333 2.6724 81.5874 71.0793
B6.PWD-Chr10.1 m 83.0 2.9275 88.7555 77.2445
B6.PWD-Chr10.2 f 74.6667 3.7793 82.097 67.2363
B6.PWD-Chr10.2 m 83.6667 5.3448 94.1748 73.1585
B6.PWD-Chr10.3 f 67.875 3.273 74.3099 61.4401
B6.PWD-Chr10.3 m 78.625 3.273 85.0599 72.1901
B6.PWD-Chr11.1 f 60.0 5.3448 70.5081 49.4919
B6.PWD-Chr11.1 m 83.0 5.3448 93.5081 72.4919
B6.PWD-Chr11.2 f 79.8 2.9275 85.5555 74.0445
B6.PWD-Chr11.2 m 100.3 2.9275 106.0555 94.5445
B6.PWD-Chr11.3 f 83.75 3.273 90.1849 77.3151
B6.PWD-Chr11.3 m 100.625 3.273 107.0599 94.1901
B6.PWD-Chr12 f 81.3333 3.0858 87.4002 75.2665
B6.PWD-Chr12 m 102.2 2.9275 107.9555 96.4445
B6.PWD-Chr13 f 80.5 3.273 86.9349 74.0651
B6.PWD-Chr13 m 93.875 3.273 100.3099 87.4401
B6.PWD-Chr14 f 81.0 2.9275 86.7555 75.2445
B6.PWD-Chr14 m 100.2 2.9275 105.9555 94.4445
B6.PWD-Chr15 f 83.125 3.273 89.5599 76.6901
B6.PWD-Chr15 m 96.25 3.273 102.6849 89.8151
B6.PWD-Chr16 f 77.875 3.273 84.3099 71.4401
B6.PWD-Chr16 m 97.125 3.273 103.5599 90.6901
B6.PWD-Chr17 f 77.4286 3.499 84.3078 70.5494
B6.PWD-Chr17 m 87.0 3.273 93.4349 80.5651
B6.PWD-Chr18 f 67.4 4.1401 75.5396 59.2604
B6.PWD-Chr18 m 73.8889 3.0858 79.9558 67.822
B6.PWD-Chr19 f 93.25 3.273 99.6849 86.8151
B6.PWD-Chr19 m 110.0 3.273 116.4349 103.5651
B6.PWD-Chr2 f 68.1429 3.499 75.022 61.2637
B6.PWD-Chr2 m 100.6 2.9275 106.3555 94.8445
B6.PWD-Chr3 f 64.625 3.273 71.0599 58.1901
B6.PWD-Chr3 m 77.2222 3.0858 83.2891 71.1553
B6.PWD-Chr5 f 70.2222 3.0858 76.2891 64.1553
B6.PWD-Chr5 m 87.2727 2.7912 92.7604 81.785
B6.PWD-Chr6 f 71.5556 3.0858 77.6224 65.4887
B6.PWD-Chr6 m 89.0 3.273 95.4349 82.5651
B6.PWD-Chr8 f 85.3333 5.3448 95.8415 74.8252
B6.PWD-Chr8 m 95.2 4.1401 103.3396 87.0604
B6.PWD-Chr9 f 69.2222 3.0858 75.2891 63.1553
B6.PWD-Chr9 m 87.875 3.273 94.3099 81.4401
B6.PWD-ChrX.1 f 89.75 3.273 96.1849 83.3151
B6.PWD-ChrX.1 m 107.75 3.273 114.1849 101.3151
B6.PWD-ChrX.2 f 86.4286 3.499 93.3078 79.5494
B6.PWD-ChrX.2 m 97.9 2.9275 103.6555 92.1445
B6.PWD-ChrX.3 f 68.25 4.6287 77.3503 59.1497
B6.PWD-ChrX.3 m 86.25 4.6287 95.3503 77.1497
B6.PWD-ChrY f 78.0 3.273 84.4349 71.5651
B6.PWD-ChrY m 99.2857 3.499 106.1649 92.4065
B6.PWD-mt f 78.0 3.273 84.4349 71.5651
B6.PWD-mt m 100.25 3.273 106.6849 93.8151
C57BL/6J f 70.125 3.273 76.5599 63.6901
C57BL/6J m 87.25 2.6724 92.5041 81.9959
PWD/PhJ f 82.4 2.9275 88.1555 76.6445
PWD/PhJ m 99.6 2.9275 105.3555 93.8445


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 91.925 2.1956 96.2417 87.6083
B6.PWD-Chr10.1 both 79.6667 1.9819 83.5632 75.7701
B6.PWD-Chr10.2 both 79.1667 3.273 85.6016 72.7318
B6.PWD-Chr10.3 both 73.25 2.3144 77.8002 68.6998
B6.PWD-Chr11.1 both 71.5 3.7793 78.9304 64.0696
B6.PWD-Chr11.2 both 90.05 2.07 94.1198 85.9802
B6.PWD-Chr11.3 both 92.1875 2.3144 96.7377 87.6373
B6.PWD-Chr12 both 91.7667 2.1268 95.948 87.5854
B6.PWD-Chr13 both 87.1875 2.3144 91.7377 82.6373
B6.PWD-Chr14 both 90.6 2.07 94.6698 86.5302
B6.PWD-Chr15 both 89.6875 2.3144 94.2377 85.1373
B6.PWD-Chr16 both 87.5 2.3144 92.0502 82.9498
B6.PWD-Chr17 both 82.2143 2.3956 86.9241 77.5044
B6.PWD-Chr18 both 70.6444 2.5818 75.7204 65.5685
B6.PWD-Chr19 both 101.625 2.3144 106.1752 97.0748
B6.PWD-Chr2 both 84.3714 2.2811 88.8561 79.8867
B6.PWD-Chr3 both 70.9236 2.2492 75.3456 66.5017
B6.PWD-Chr5 both 78.7475 2.0805 82.8378 74.6572
B6.PWD-Chr6 both 80.2778 2.2492 84.6997 75.8558
B6.PWD-Chr8 both 90.2667 3.3803 96.9126 83.6207
B6.PWD-Chr9 both 78.5486 2.2492 82.9706 74.1267
B6.PWD-ChrX.1 both 98.75 2.3144 103.3002 94.1998
B6.PWD-ChrX.2 both 92.1643 2.2811 96.649 87.6796
B6.PWD-ChrX.3 both 77.25 3.273 83.6849 70.8151
B6.PWD-ChrY both 88.6429 2.3956 93.3527 83.933
B6.PWD-mt both 89.125 2.3144 93.6752 84.5748
C57BL/6J both 78.6875 2.1127 82.8412 74.5338
PWD/PhJ both 91.0 2.07 95.0698 86.9302