Project measure / variable:   Svenson3   Fib

ID, description, units MPD:27343   Fib   blood fibrinogen   [mg/dL]  
Data set, strains Svenson3   B6.PWD consomic w/par   23 strains     sex: both     age: 6wks
Procedure coagulation test
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  STRAIN COMPARISON PLOT
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Svenson3 - blood fibrinogen



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains23 strains
Mean of the strain means177   mg/dL 222   mg/dL
Median of the strain means182   mg/dL 223   mg/dL
SD of the strain means± 23.8 ± 25.5
Coefficient of variation (CV)0.134 0.115
Min–max range of strain means112   –   217   mg/dL 136   –   258   mg/dL
Mean sample size per strain7.8   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 164239.1481 164239.1481 155.5925 < 0.0001
strain 21 125100.6167 5957.1722 5.6435 < 0.0001
sex:strain 21 30313.1424 1443.483 1.3675 0.1323
Residuals 301 317727.354 1055.5726


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 169.0 15.7   4 7.86 0.0928 156.0, 187.0 -0.35
B6.PWD-Chr1 m 220.0 17.1   3 9.86 0.0776 209.0, 240.0 -0.08
B6.PWD-Chr11.1 f 169.0 39.0   9 13.0 0.231 74.3, 209.0 -0.35
B6.PWD-Chr11.1 m 238.0 25.2   8 8.91 0.106 186.0, 270.0 0.63
B6.PWD-Chr11.2 f 200.0 30.1   9 10.0 0.15 150.0, 241.0 0.95
B6.PWD-Chr11.2 m 220.0 27.5   7 10.4 0.125 188.0, 258.0 -0.08
B6.PWD-Chr11.3 f 194.0 26.3   8 9.31 0.136 148.0, 231.0 0.7
B6.PWD-Chr11.3 m 236.0 26.9   8 9.5 0.114 195.0, 283.0 0.55
B6.PWD-Chr12 f 201.0 17.1   8 6.06 0.0853 172.0, 228.0 1.0
B6.PWD-Chr12 m 238.0 43.5   8 15.4 0.183 138.0, 272.0 0.63
B6.PWD-Chr13 m 258.0 7.71   2   5.45 0.0299 252.0, 263.0 1.41
B6.PWD-Chr14 f 198.0 17.9   8 6.33 0.0906 175.0, 224.0 0.87
B6.PWD-Chr14 m 232.0 69.5   8 24.6 0.299 75.5, 300.0 0.39
B6.PWD-Chr15 f 198.0 24.2   8 8.56 0.123 166.0, 248.0 0.87
B6.PWD-Chr15 m 223.0 22.2   7 8.39 0.0995 196.0, 260.0 0.04
B6.PWD-Chr16 f 150.0 19.7   8 6.96 0.131 118.0, 179.0 -1.15
B6.PWD-Chr16 m 200.0 28.3   8 10.0 0.142 166.0, 233.0 -0.86
B6.PWD-Chr17 f 157.0 23.3   8 8.24 0.148 118.0, 191.0 -0.85
B6.PWD-Chr17 m 240.0 13.5   9 4.51 0.0563 218.0, 260.0 0.71
B6.PWD-Chr18 f 184.0 19.8   11 5.97 0.107 148.0, 210.0 0.28
B6.PWD-Chr18 m 202.0 18.0   8 6.36 0.0889 174.0, 223.0 -0.78
B6.PWD-Chr19 f 217.0 35.6   8 12.6 0.164 176.0, 284.0 1.67
B6.PWD-Chr19 m 256.0 23.6   10 7.47 0.0921 206.0, 297.0 1.33
B6.PWD-Chr2 f 178.0 25.0   9 8.33 0.14 134.0, 227.0 0.03
B6.PWD-Chr2 m 215.0 34.5   10 10.9 0.161 170.0, 268.0 -0.27
B6.PWD-Chr3 f 112.0 20.3   4 10.1 0.181 100.0, 142.0 -2.74
B6.PWD-Chr3 m 136.0 20.9   4 10.4 0.154 123.0, 167.0 -3.37
B6.PWD-Chr5 f 190.0 14.8   5 6.62 0.0779 167.0, 205.0 0.53
B6.PWD-Chr5 m 218.0 27.7   12 8.01 0.127 175.0, 253.0 -0.16
B6.PWD-Chr6 f 142.0 35.0   10 11.1 0.246 63.5, 177.0 -1.48
B6.PWD-Chr6 m 203.0 45.2   7 17.1 0.223 142.0, 264.0 -0.74
B6.PWD-Chr9 f 184.0 41.4   6 16.9 0.225 127.0, 233.0 0.28
B6.PWD-Chr9 m 251.0 22.8   3 13.1 0.0907 226.0, 270.0 1.14
B6.PWD-ChrX.1 f 175.0 34.0   10 10.8 0.195 83.2, 209.0 -0.1
B6.PWD-ChrX.1 m 199.0 43.8   8 15.5 0.22 123.0, 262.0 -0.9
B6.PWD-ChrX.3 f 166.0 20.0   9 6.68 0.121 146.0, 200.0 -0.47
B6.PWD-ChrX.3 m 222.0 23.8   8 8.41 0.107 184.0, 251.0 0.0
B6.PWD-ChrY f 186.0 21.0   8 7.44 0.113 144.0, 207.0 0.37
B6.PWD-ChrY m 237.0 21.0   8 7.42 0.0886 205.0, 256.0 0.59
B6.PWD-mt f 196.0 35.4   8 12.5 0.181 146.0, 248.0 0.79
B6.PWD-mt m 225.0 40.9   8 14.5 0.182 188.0, 306.0 0.12
C57BL/6J f 155.0 15.3   10 4.85 0.0987 137.0, 181.0 -0.94
C57BL/6J m 232.0 30.2   10 9.57 0.131 201.0, 305.0 0.39
PWD/PhJ f 179.0 87.0   4 43.5 0.487 48.3, 229.0 0.07
PWD/PhJ m 204.0 59.0   11 17.8 0.289 96.7, 283.0 -0.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 169.45 16.2448 201.4177 137.4823
B6.PWD-Chr1 m 220.1667 18.7579 257.0798 183.2535
B6.PWD-Chr11.1 f 169.0333 10.8299 190.3452 147.7215
B6.PWD-Chr11.1 m 237.6625 11.4868 260.2671 215.0579
B6.PWD-Chr11.2 f 200.2667 10.8299 221.5785 178.9548
B6.PWD-Chr11.2 m 220.0429 12.2799 244.2082 195.8775
B6.PWD-Chr11.3 f 194.15 11.4868 216.7546 171.5454
B6.PWD-Chr11.3 m 235.925 11.4868 258.5296 213.3204
B6.PWD-Chr12 f 200.775 11.4868 223.3796 178.1704
B6.PWD-Chr12 m 238.0 11.4868 260.6046 215.3954
B6.PWD-Chr14 f 197.725 11.4868 220.3296 175.1204
B6.PWD-Chr14 m 232.3 11.4868 254.9046 209.6954
B6.PWD-Chr15 f 197.5 11.4868 220.1046 174.8954
B6.PWD-Chr15 m 223.1286 12.2799 247.2939 198.9632
B6.PWD-Chr16 f 150.0875 11.4868 172.6921 127.4829
B6.PWD-Chr16 m 199.9125 11.4868 222.5171 177.3079
B6.PWD-Chr17 f 157.1625 11.4868 179.7671 134.5579
B6.PWD-Chr17 m 240.1111 10.8299 261.4229 218.7993
B6.PWD-Chr18 f 184.3273 9.796 203.6045 165.05
B6.PWD-Chr18 m 202.35 11.4868 224.9546 179.7454
B6.PWD-Chr19 f 217.275 11.4868 239.8796 194.6704
B6.PWD-Chr19 m 256.38 10.2741 276.5982 236.1618
B6.PWD-Chr2 f 178.3444 10.8299 199.6563 157.0326
B6.PWD-Chr2 m 214.81 10.2741 235.0282 194.5918
B6.PWD-Chr3 f 112.1 16.2448 144.0677 80.1323
B6.PWD-Chr3 m 135.95 16.2448 167.9177 103.9823
B6.PWD-Chr5 f 190.04 14.5298 218.6328 161.4472
B6.PWD-Chr5 m 217.9917 9.3789 236.4482 199.5351
B6.PWD-Chr6 f 141.9 10.2741 162.1182 121.6818
B6.PWD-Chr6 m 202.7857 12.2799 226.9511 178.6204
B6.PWD-Chr9 f 183.7167 13.2638 209.8182 157.6151
B6.PWD-Chr9 m 250.8667 18.7579 287.7798 213.9535
B6.PWD-ChrX.1 f 174.63 10.2741 194.8482 154.4118
B6.PWD-ChrX.1 m 199.4875 11.4868 222.0921 176.8829
B6.PWD-ChrX.3 f 165.6 10.8299 186.9118 144.2882
B6.PWD-ChrX.3 m 221.6375 11.4868 244.2421 199.0329
B6.PWD-ChrY f 186.1875 11.4868 208.7921 163.5829
B6.PWD-ChrY m 237.0375 11.4868 259.6421 214.4329
B6.PWD-mt f 196.0125 11.4868 218.6171 173.4079
B6.PWD-mt m 224.7375 11.4868 247.3421 202.1329
C57BL/6J f 155.3 10.2741 175.5182 135.0818
C57BL/6J m 231.5 10.2741 251.7182 211.2818
PWD/PhJ f 178.575 16.2448 210.5427 146.6073
PWD/PhJ m 204.1545 9.796 223.4318 184.8773


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 194.8083 12.4072 219.2241 170.3926
B6.PWD-Chr11.1 both 203.3479 7.8935 218.8814 187.8144
B6.PWD-Chr11.2 both 210.1548 8.1866 226.265 194.0445
B6.PWD-Chr11.3 both 215.0375 8.1224 231.0214 199.0536
B6.PWD-Chr12 both 219.3875 8.1224 235.3714 203.4036
B6.PWD-Chr14 both 215.0125 8.1224 230.9964 199.0286
B6.PWD-Chr15 both 210.3143 8.4075 226.8592 193.7694
B6.PWD-Chr16 both 175.0 8.1224 190.9839 159.0161
B6.PWD-Chr17 both 198.6368 7.8935 214.1703 183.1033
B6.PWD-Chr18 both 193.3386 7.5483 208.1928 178.4845
B6.PWD-Chr19 both 236.8275 7.7056 251.9911 221.6639
B6.PWD-Chr2 both 196.5772 7.464 211.2654 181.8891
B6.PWD-Chr3 both 124.025 11.4868 146.6296 101.4204
B6.PWD-Chr5 both 204.0158 8.6469 221.032 186.9997
B6.PWD-Chr6 both 172.3429 8.0055 188.0967 156.589
B6.PWD-Chr9 both 217.2917 11.4868 239.8963 194.6871
B6.PWD-ChrX.1 both 187.0587 7.7056 202.2224 171.8951
B6.PWD-ChrX.3 both 193.6187 7.8935 209.1523 178.0852
B6.PWD-ChrY both 211.6125 8.1224 227.5964 195.6286
B6.PWD-mt both 210.375 8.1224 226.3589 194.3911
C57BL/6J both 193.4 7.2649 207.6964 179.1036
PWD/PhJ both 191.3648 9.4849 210.0299 172.6996




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA