Project measure / variable:   Jaxwest1   HR_cv

ID, description, units MPD:15110   HR_cv   heart rate coefficient of variance   [%]  
Data set, strains Jaxwest1   inbred   7 strains     sex: both     age: 8-10wks
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  STRAIN COMPARISON PLOT
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Jaxwest1 - heart rate coefficient of variance



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means45.0   % 37.3   %
Median of the strain means46.0   % 43.4   %
SD of the strain means± 7.74 ± 16.4
Coefficient of variation (CV)0.172 0.439
Min–max range of strain means31.7   –   57.6   % 1.12   –   49.1   %
Mean sample size per strain7.9   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1055.6627 1055.6627 12.2524 0.0007
strain 6 7147.0924 1191.1821 13.8253 < 0.0001
sex:strain 6 5659.2203 943.2034 10.9472 < 0.0001
Residuals 93 8012.8515 86.1597


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 46.8 4.88   8 1.72 0.104 36.2, 52.2 0.23
129S1/SvImJ m 44.5 4.73   8 1.67 0.106 38.4, 51.6 0.44
A/J f 46.0 5.33   8 1.89 0.116 40.5, 57.7 0.13
A/J m 49.1 8.07   8 2.85 0.164 40.7, 61.8 0.72
BALB/cJ f 57.6 9.03   7 3.41 0.157 47.4, 72.1 1.62
BALB/cJ m 43.4 17.3   8 6.13 0.4 2.6, 57.3 0.38
C57BL/6J f 44.1 10.5   8 3.73 0.239 20.5, 56.0 -0.12
C57BL/6J m 36.9 16.2   7 6.12 0.439 0.5, 45.9 -0.02
DBA/2J f 47.5 2.91   8 1.03 0.0612 44.9, 52.2 0.32
DBA/2J m 44.6 10.5   7 3.99 0.236 38.7, 68.3 0.45
NOD/ShiLtJ f 31.7 12.2   8 4.33 0.386 1.5, 37.6 -1.72
NOD/ShiLtJ m 41.2 4.53   8 1.6 0.11 37.8, 49.6 0.24
SJL/J f 41.5 4.9   8 1.73 0.118 35.0, 48.6 -0.46
SJL/J m 1.12 0.546   6 0.223 0.489 0.6, 2.1 -2.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 46.775 3.2818 53.2919 40.2581
129S1/SvImJ m 44.525 3.2818 51.0419 38.0081
A/J f 46.0 3.2818 52.5169 39.4831
A/J m 49.1375 3.2818 55.6544 42.6206
BALB/cJ f 57.5571 3.5084 64.524 50.5903
BALB/cJ m 43.3625 3.2818 49.8794 36.8456
C57BL/6J f 44.1 3.2818 50.6169 37.5831
C57BL/6J m 36.9143 3.5084 43.8812 29.9474
DBA/2J f 47.55 3.2818 54.0669 41.0331
DBA/2J m 44.6 3.5084 51.5669 37.6331
NOD/ShiLtJ f 31.725 3.2818 38.2419 25.2081
NOD/ShiLtJ m 41.175 3.2818 47.6919 34.6581
SJL/J f 41.5 3.2818 48.0169 34.9831
SJL/J m 1.1167 3.7895 8.6418 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 45.65 2.3206 50.2582 41.0418
A/J both 47.5687 2.3206 52.1769 42.9606
BALB/cJ both 50.4598 2.402 55.2297 45.6899
C57BL/6J both 40.5071 2.402 45.277 35.7372
DBA/2J both 46.075 2.402 50.8449 41.3051
NOD/ShiLtJ both 36.45 2.3206 41.0582 31.8418
SJL/J both 21.3083 2.5065 26.2857 16.3309




  GWAS USING LINEAR MIXED MODELS