Project measure / variable:   Jaxwest1   BMC

ID, description, units MPD:15131   BMC   bone mineral content (BMC)   [g]  
Data set, strains Jaxwest1   inbred   7 strains     sex: both     age: 11-13wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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Jaxwest1 - bone mineral content (BMC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means0.454   g 0.493   g
Median of the strain means0.489   g 0.514   g
SD of the strain means± 0.0635 ± 0.0730
Coefficient of variation (CV)0.140 0.148
Min–max range of strain means0.340   –   0.510   g 0.388   –   0.576   g
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0451 0.0451 30.1473 < 0.0001
strain 6 0.413 0.0688 46.0492 < 0.0001
sex:strain 6 0.0318 0.0053 3.5498 0.0032
Residuals 97 0.145 0.0015


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.489 0.045   8 0.0159 0.092 0.432, 0.582 0.54
129S1/SvImJ m 0.541 0.0587   8 0.0207 0.108 0.42, 0.613 0.65
A/J f 0.34 0.0338   8 0.012 0.0995 0.294, 0.372 -1.8
A/J m 0.388 0.0197   8 0.00696 0.0508 0.358, 0.416 -1.44
BALB/cJ f 0.5 0.027   8 0.00956 0.054 0.457, 0.53 0.72
BALB/cJ m 0.559 0.0291   8 0.0103 0.0521 0.529, 0.608 0.9
C57BL/6J f 0.395 0.0261   8 0.00922 0.066 0.346, 0.436 -0.94
C57BL/6J m 0.458 0.0176   8 0.00622 0.0384 0.432, 0.482 -0.48
DBA/2J f 0.458 0.057   8 0.0202 0.125 0.374, 0.519 0.06
DBA/2J m 0.417 0.0361   7 0.0136 0.0864 0.341, 0.451 -1.04
NOD/ShiLtJ f 0.51 0.0494   8 0.0175 0.0968 0.449, 0.588 0.88
NOD/ShiLtJ m 0.576 0.0131   8 0.00464 0.0228 0.55, 0.589 1.13
SJL/J f 0.489 0.056   8 0.0198 0.115 0.403, 0.584 0.54
SJL/J m 0.514 0.0321   8 0.0114 0.0625 0.482, 0.582 0.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.4893 0.0137 0.5164 0.4621
129S1/SvImJ m 0.5408 0.0137 0.5679 0.5136
A/J f 0.3399 0.0137 0.367 0.3127
A/J m 0.3878 0.0137 0.4149 0.3606
BALB/cJ f 0.5004 0.0137 0.5275 0.4732
BALB/cJ m 0.5594 0.0137 0.5865 0.5322
C57BL/6J f 0.3949 0.0137 0.422 0.3677
C57BL/6J m 0.458 0.0137 0.4851 0.4309
DBA/2J f 0.4576 0.0137 0.4848 0.4305
DBA/2J m 0.4174 0.0146 0.4464 0.3884
NOD/ShiLtJ f 0.5104 0.0137 0.5375 0.4832
NOD/ShiLtJ m 0.576 0.0137 0.6031 0.5489
SJL/J f 0.4886 0.0137 0.5158 0.4615
SJL/J m 0.5141 0.0137 0.5413 0.487


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.515 0.0097 0.5342 0.4958
A/J both 0.3638 0.0097 0.383 0.3446
BALB/cJ both 0.5299 0.0097 0.5491 0.5107
C57BL/6J both 0.4264 0.0097 0.4456 0.4073
DBA/2J both 0.4375 0.01 0.4574 0.4177
NOD/ShiLtJ both 0.5432 0.0097 0.5624 0.524
SJL/J both 0.5014 0.0097 0.5206 0.4822




  GWAS USING LINEAR MIXED MODELS