Project measure / variable:   Jaxwest1   BP

ID, description, units MPD:15112   BP   systolic blood pressure   [mmHg]  
Data set, strains Jaxwest1   inbred   7 strains     sex: both     age: 9-14wks
Procedure tail cuff
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  STRAIN COMPARISON PLOT
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Jaxwest1 - systolic blood pressure



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means123   mmHg 120   mmHg
Median of the strain means124   mmHg 122   mmHg
SD of the strain means± 6.23 ± 4.47
Coefficient of variation (CV)0.0506 0.0371
Min–max range of strain means112   –   131   mmHg 115   –   128   mmHg
Mean sample size per strain6.9   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 112.2636 112.2636 0.3749 0.5419
strain 6 1583.485 263.9142 0.8813 0.5121
sex:strain 6 1011.5917 168.5986 0.563 0.7586
Residuals 88 26352.2381 299.4573


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 131.0 27.5   6 11.2 0.211 97.0, 165.0 1.26
129S1/SvImJ m 128.0 20.3   8 7.18 0.159 106.0, 169.0 1.7
A/J f 124.0 15.0   6 6.11 0.12 104.0, 147.0 0.14
A/J m 116.0 14.0   6 5.72 0.121 98.0, 137.0 -0.99
BALB/cJ f 126.0 28.8   6 11.8 0.228 93.0, 166.0 0.46
BALB/cJ m 122.0 12.2   8 4.33 0.101 108.0, 143.0 0.35
C57BL/6J f 121.0 11.5   7 4.34 0.0953 102.0, 135.0 -0.34
C57BL/6J m 122.0 18.8   8 6.64 0.154 85.0, 151.0 0.35
DBA/2J f 112.0 11.4   8 4.04 0.102 102.0, 137.0 -1.79
DBA/2J m 122.0 13.4   8 4.73 0.11 104.0, 142.0 0.35
NOD/ShiLtJ f 128.0 18.3   7 6.91 0.143 109.0, 152.0 0.78
NOD/ShiLtJ m 118.0 10.8   8 3.82 0.0916 102.0, 135.0 -0.54
SJL/J f 120.0 14.2   8 5.01 0.118 96.0, 144.0 -0.5
SJL/J m 115.0 19.8   8 6.98 0.172 87.0, 145.0 -1.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 130.6667 7.0647 144.7062 116.6271
129S1/SvImJ m 127.875 6.1182 140.0336 115.7164
A/J f 124.1667 7.0647 138.2062 110.1271
A/J m 115.5 7.0647 129.5395 101.4605
BALB/cJ f 126.0 7.0647 140.0395 111.9605
BALB/cJ m 121.5 6.1182 133.6586 109.3414
C57BL/6J f 120.5714 6.5406 133.5695 107.5733
C57BL/6J m 121.5 6.1182 133.6586 109.3414
DBA/2J f 111.875 6.1182 124.0336 99.7164
DBA/2J m 121.75 6.1182 133.9086 109.5914
NOD/ShiLtJ f 127.8571 6.5406 140.8552 114.8591
NOD/ShiLtJ m 117.875 6.1182 130.0336 105.7164
SJL/J f 119.625 6.1182 131.7836 107.4664
SJL/J m 115.0 6.1182 127.1586 102.8414


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 129.2708 4.6728 138.5571 119.9845
A/J both 119.8333 4.9955 129.7608 109.9059
BALB/cJ both 123.75 4.6728 133.0363 114.4637
C57BL/6J both 121.0357 4.4781 129.9349 112.1365
DBA/2J both 116.8125 4.3262 125.4099 108.2151
NOD/ShiLtJ both 122.8661 4.4781 131.7653 113.9669
SJL/J both 117.3125 4.3262 125.9099 108.7151




  GWAS USING LINEAR MIXED MODELS