Project measure / variable:   Jaxwest1   QT

ID, description, units MPD:15105   QT   interval between peak of Q-wave to end of T-wave (QT)   [ms]  
Data set, strains Jaxwest1   inbred   7 strains     sex: both     age: 8-10wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Jaxwest1 - interval between peak of Q-wave to end of T-wave (QT)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means49.0   ms 46.7   ms
Median of the strain means50.5   ms 47.1   ms
SD of the strain means± 4.45 ± 4.58
Coefficient of variation (CV)0.0909 0.0980
Min–max range of strain means41.9   –   55.1   ms 37.3   –   51.0   ms
Mean sample size per strain7.9   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 83.412 83.412 4.2007 0.0432
strain 6 1341.8512 223.6419 11.2629 < 0.0001
sex:strain 6 386.5774 64.4296 3.2447 0.0061
Residuals 93 1846.6599 19.8566


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 50.9 4.75   8 1.68 0.0932 40.3, 55.3 0.43
129S1/SvImJ m 49.4 4.62   8 1.63 0.0935 42.8, 56.6 0.58
A/J f 49.0 3.73   8 1.32 0.076 44.4, 56.2 0.0
A/J m 51.0 4.41   8 1.56 0.0864 44.8, 56.9 0.93
BALB/cJ f 55.1 4.27   7 1.61 0.0774 50.1, 61.2 1.37
BALB/cJ m 50.0 4.92   8 1.74 0.0985 42.2, 57.6 0.71
C57BL/6J f 51.1 4.8   8 1.7 0.0939 45.0, 58.5 0.47
C57BL/6J m 46.1 5.62   7 2.13 0.122 34.4, 51.0 -0.14
DBA/2J f 50.5 2.52   8 0.892 0.05 45.5, 54.0 0.34
DBA/2J m 47.1 7.27   7 2.75 0.154 42.4, 63.3 0.08
NOD/ShiLtJ f 41.9 3.41   8 1.2 0.0813 34.0, 44.9 -1.59
NOD/ShiLtJ m 46.2 2.82   8 0.997 0.061 43.8, 52.8 -0.12
SJL/J f 44.4 4.46   8 1.58 0.1 38.2, 50.1 -1.03
SJL/J m 37.3 2.78   6 1.13 0.0744 34.5, 42.3 -2.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 50.925 1.5755 54.0535 47.7965
129S1/SvImJ m 49.4375 1.5755 52.566 46.309
A/J f 49.025 1.5755 52.1535 45.8965
A/J m 51.0125 1.5755 54.141 47.884
BALB/cJ f 55.1 1.6842 58.4446 51.7554
BALB/cJ m 49.975 1.5755 53.1035 46.8465
C57BL/6J f 51.1125 1.5755 54.241 47.984
C57BL/6J m 46.1286 1.6842 49.4731 42.784
DBA/2J f 50.45 1.5755 53.5785 47.3215
DBA/2J m 47.1143 1.6842 50.4588 43.7697
NOD/ShiLtJ f 41.9375 1.5755 45.066 38.809
NOD/ShiLtJ m 46.225 1.5755 49.3535 43.0965
SJL/J f 44.3875 1.5755 47.516 41.259
SJL/J m 37.3333 1.8192 40.9459 33.7208


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 50.1813 1.114 52.3935 47.969
A/J both 50.0187 1.114 52.231 47.8065
BALB/cJ both 52.5375 1.1531 54.8274 50.2476
C57BL/6J both 48.6205 1.1531 50.9104 46.3307
DBA/2J both 48.7821 1.1531 51.072 46.4923
NOD/ShiLtJ both 44.0813 1.114 46.2935 41.869
SJL/J both 40.8604 1.2033 43.2499 38.4709




  GWAS USING LINEAR MIXED MODELS