Project measure / variable:   Jaxwest1   BMC_spine

ID, description, units MPD:15135   BMC_spine   bone mineral content (BMC) of spine   [g]  
Data set, strains Jaxwest1   inbred   7 strains     sex: both     age: 11-13wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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Jaxwest1 - bone mineral content (BMC) of spine



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means0.0481   g 0.0494   g
Median of the strain means0.0496   g 0.0494   g
SD of the strain means± 0.00654 ± 0.00695
Coefficient of variation (CV)0.136 0.141
Min–max range of strain means0.0384   –   0.0573   g 0.0396   –   0.0586   g
Mean sample size per strain7.9   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0001 0.0001 1.3707 0.2446
strain 6 0.0039 0.0006 14.4301 < 0.0001
sex:strain 6 0.0004 0.0001 1.5394 0.1737
Residuals 95 0.0042 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0539 0.00832   8 0.00294 0.154 0.0416, 0.0668 0.89
129S1/SvImJ m 0.0586 0.011   8 0.00389 0.188 0.0425, 0.0757 1.33
A/J f 0.044 0.00431   8 0.00152 0.098 0.0383, 0.0532 -0.62
A/J m 0.0474 0.00351   8 0.00124 0.0742 0.0425, 0.0533 -0.28
BALB/cJ f 0.0498 0.00849   7 0.00321 0.171 0.0385, 0.0667 0.27
BALB/cJ m 0.0494 0.00846   7 0.0032 0.171 0.0409, 0.0674 0.01
C57BL/6J f 0.0384 0.00615   8 0.00217 0.16 0.0313, 0.0463 -1.48
C57BL/6J m 0.042 0.00185   8 0.000655 0.0442 0.0399, 0.0446 -1.06
DBA/2J f 0.0434 0.00821   8 0.0029 0.189 0.0275, 0.0548 -0.71
DBA/2J m 0.0396 0.00648   7 0.00245 0.164 0.0282, 0.0488 -1.4
NOD/ShiLtJ f 0.0573 0.00411   8 0.00145 0.0718 0.0531, 0.0653 1.41
NOD/ShiLtJ m 0.0529 0.00385   8 0.00136 0.0727 0.0485, 0.0611 0.51
SJL/J f 0.0496 0.00745   8 0.00263 0.15 0.0419, 0.0619 0.24
SJL/J m 0.0556 0.00543   8 0.00192 0.0977 0.0466, 0.065 0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0539 0.0024 0.0586 0.0492
129S1/SvImJ m 0.0586 0.0024 0.0633 0.0539
A/J f 0.0439 0.0024 0.0486 0.0393
A/J m 0.0474 0.0024 0.0521 0.0427
BALB/cJ f 0.0498 0.0025 0.0548 0.0448
BALB/cJ m 0.0494 0.0025 0.0544 0.0444
C57BL/6J f 0.0384 0.0024 0.0431 0.0337
C57BL/6J m 0.042 0.0024 0.0467 0.0373
DBA/2J f 0.0434 0.0024 0.0481 0.0387
DBA/2J m 0.0396 0.0025 0.0446 0.0345
NOD/ShiLtJ f 0.0573 0.0024 0.062 0.0526
NOD/ShiLtJ m 0.0529 0.0024 0.0576 0.0482
SJL/J f 0.0496 0.0024 0.0543 0.0449
SJL/J m 0.0556 0.0024 0.0603 0.0509


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0563 0.0017 0.0596 0.0529
A/J both 0.0457 0.0017 0.049 0.0423
BALB/cJ both 0.0496 0.0018 0.0532 0.0461
C57BL/6J both 0.0402 0.0017 0.0435 0.0369
DBA/2J both 0.0415 0.0017 0.0449 0.0381
NOD/ShiLtJ both 0.0551 0.0017 0.0584 0.0518
SJL/J both 0.0526 0.0017 0.0559 0.0493




  GWAS USING LINEAR MIXED MODELS