Project measure / variable:   Jaxwest1   RR

ID, description, units MPD:15107   RR   interval between R-waves (RR)   [ms]  
Data set, strains Jaxwest1   inbred   7 strains     sex: both     age: 8-10wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Jaxwest1 - interval between R-waves (RR)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means89.5   ms 85.8   ms
Median of the strain means88.2   ms 84.5   ms
SD of the strain means± 11.5 ± 5.75
Coefficient of variation (CV)0.128 0.0670
Min–max range of strain means70.2   –   109   ms 80.0   –   92.5   ms
Mean sample size per strain7.9   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 248.8972 248.8972 2.5051 0.1169
strain 6 5188.2965 864.7161 8.7033 < 0.0001
sex:strain 6 2237.4374 372.9062 3.7533 0.0022
Residuals 93 9240.0112 99.355


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 86.5 4.04   8 1.43 0.0468 83.0, 95.0 -0.26
129S1/SvImJ m 84.5 5.42   8 1.92 0.0641 74.1, 92.0 -0.23
A/J f 88.2 8.47   8 2.99 0.0961 81.9, 107.0 -0.11
A/J m 92.5 15.7   8 5.56 0.17 75.8, 118.0 1.16
BALB/cJ f 109.0 17.8   7 6.71 0.163 89.5, 140.0 1.7
BALB/cJ m 92.5 7.59   8 2.68 0.082 83.6, 106.0 1.16
C57BL/6J f 94.3 9.59   8 3.39 0.102 83.8, 108.0 0.42
C57BL/6J m 80.0 4.59   7 1.73 0.0573 74.1, 88.2 -1.01
DBA/2J f 90.5 9.68   8 3.42 0.107 80.9, 104.0 0.09
DBA/2J m 90.1 15.9   7 6.01 0.176 77.6, 125.0 0.74
NOD/ShiLtJ f 70.2 1.24   8 0.439 0.0177 68.9, 72.1 -1.68
NOD/ShiLtJ m 81.1 12.2   8 4.3 0.15 70.8, 105.0 -0.82
SJL/J f 87.7 5.36   8 1.9 0.0611 80.9, 95.9 -0.16
SJL/J m 80.1 6.4   6 2.61 0.0799 73.9, 91.5 -1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 86.475 3.5241 93.4732 79.4768
129S1/SvImJ m 84.525 3.5241 91.5232 77.5268
A/J f 88.1625 3.5241 95.1607 81.1643
A/J m 92.525 3.5241 99.5232 85.5268
BALB/cJ f 109.1286 3.7674 116.61 101.6472
BALB/cJ m 92.55 3.5241 99.5482 85.5518
C57BL/6J f 94.2625 3.5241 101.2607 87.2643
C57BL/6J m 80.0286 3.7674 87.51 72.5472
DBA/2J f 90.4625 3.5241 97.4607 83.4643
DBA/2J m 90.0714 3.7674 97.5528 82.59
NOD/ShiLtJ f 70.25 3.5241 77.2482 63.2518
NOD/ShiLtJ m 81.05 3.5241 88.0482 74.0518
SJL/J f 87.7375 3.5241 94.7357 80.7393
SJL/J m 80.1167 4.0693 88.1975 72.0359


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 85.5 2.4919 90.4485 80.5515
A/J both 90.3437 2.4919 95.2922 85.3953
BALB/cJ both 100.8393 2.5794 105.9614 95.7171
C57BL/6J both 87.1455 2.5794 92.2677 82.0234
DBA/2J both 90.267 2.5794 95.3891 85.1448
NOD/ShiLtJ both 75.65 2.4919 80.5985 70.7015
SJL/J both 83.9271 2.6916 89.272 78.5821




  GWAS USING LINEAR MIXED MODELS