MPD: Phenotype measures mapped to VT:0008077, CD8-positive T cell quantity

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Donahue5:12	Donahue5	immune cell quantification	(none)	CD8 T cells (percentage of viable WBC) [%] pct_CD8 41412	B6.A consomic w/par	22	both	7wks	N=8	2011

Donahue6:11	Donahue6	immune cell quantification	(none)	CD8 T cells (percentage of viable WBC) [%] pct_CD8 41511	B6.PWD consomic w/par	28	both	7wks	N=8	2011

Farmer1:35	Farmer1	immune cell quantification	(none)	percentage of viable CD8⁺ T cells in 150 µl collected blood [%] CD8 11335	QTL population		both	6wks	N=206	2001

Graham1:45	Graham1	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are CD8+ in brain, post infection [%] CD8_brain 63345 day 7 day 12 day 21 day 28	CC RIX	5	m	8-10wks	N=3	2015

Graham1:49	Graham1	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are CD8+ in spleen, post infection [%] CD8_spleen 63349 day 7 day 12 day 21 day 28	CC RIX	2	m	8-10wks	N=3	2015

Graham1:53	Graham1	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are NS4b+ in brain, post infection [%] NS4b_brain 63353 day 7 day 12 day 21 day 28	CC RIX	5	m	8-10wks	N=3	2015

Graham1:57	Graham1	immune cell quantification	West Nile virus	percentage of CD3+ T cells that are NS4b+ in spleen, post infection [%] NS4b_spleen 63357 day 7 day 12 day 21 day 28	CC RIX	2	m	8-10wks	N=3	2015

Graham3:22	Graham3	immune cell quantification	(none)	percentage of splenic CD3+ T cells that are CD8+ (memory precursor panel) [%] mp_CD3_pos_CD8_pos 113813	CC RIX	92	m	8-10wks	N=4	2021

Graham3:23	Graham3	immune cell quantification	(none)	percentage of splenic CD8+ T cells that are CD44+ (memory precursor panel) [%] mp_CD8_pos_CD44_pos 113814	CC RIX	91	m	8-10wks	N=4	2021

Graham3:24	Graham3	immune cell quantification	(none)	percentage of splenic CD8+ T cells that are CD62L- (memory precursor panel) [%] mp_CD8_pos_CD62L_neg 113815	CC RIX	76	m	8-10wks	N=3	2021

Graham3:25	Graham3	immune cell quantification	(none)	percentage of splenic CD8+ T cells that are Ki67+ (memory precursor panel) [%] mp_CD8_pos_Ki67_pos 113816	CC RIX	92	m	8-10wks	N=4	2021

Graham3:35	Graham3	immune cell quantification	(none)	percentage of splenic CD3+ T cells that are CD8+ (memory panel) [%] mem_CD3_pos_CD8_pos 113826	CC RIX	68	m	8-10wks	N=3	2021

Graham3:36	Graham3	immune cell quantification	(none)	percentage of splenic CD8+ T cells that are CD44+ (memory panel) [%] mem_CD8_pos_CD44_pos 113827	CC RIX	73	m	8-10wks	N=3	2021

Graham3:37	Graham3	immune cell quantification	(none)	percentage of splenic CD8+ T cells that are CD62L- (memory panel) [%] mem_CD8_pos_CD62L_neg 113828	CC RIX	68	m	8-10wks	N=3	2021

Graham3:38	Graham3	immune cell quantification	(none)	percentage of splenic CD8+ T cells that are Ki67+ (memory panel) [%] mem_CD8_pos_Ki67_pos 113829	CC RIX	73	m	8-10wks	N=3	2021

Graham3:48	Graham3	immune cell quantification	(none)	percentage of splenic CD3+ T cells that are CD8+ following stimulation with anti-CD3 and anti-CD28 [%] ics_CD3_pos_CD8_pos 113839	CC RIX	102	m	8-10wks	N=4	2021

Graham3:49	Graham3	immune cell quantification	(none)	percentage of splenic CD8+ T cells that are IL-17+ by intracellular cytokine staining following stimulation with anti-CD3 and anti-CD28 [%] ics_CD8_pos_IL17_pos 113840	CC RIX	102	m	8-10wks	N=4	2021

Graham3:50	Graham3	immune cell quantification	(none)	percentage of splenic CD8+ T cells that are IFNg+ by intracellular cytokine staining following stimulation with anti-CD3 and anti-CD28 [%] ics_CD8_pos_IGNg_pos 113841	CC RIX	102	m	8-10wks	N=4	2021

Hackstein1:15	Hackstein1	immune cell quantification	(none)	bronchoalveolar lavage CD3+ CD8+ T cells (percentage of CD45+ cells) [%] T_CD8 49115	inbred	5	m	7-11wks	N=9	2012

Jaxpheno6:3	Jaxpheno6	immune cell quantification	(none)	splenic CD8 T cells (percentage of total viable cells) [%] pct_CD8 23103 8wks 16wks	inbred	11	both		N=9	2006

Lesage1:18	Lesage1	immune cell quantification	(none)	percentage of splenic T cells that are CD4- CD8+ [%] CD4_neg_CD8_pos_of_Tcells 63518	CC w/par	65	both	5-8wks	N=2	2018

Lesage1:19	Lesage1	immune cell quantification	(none)	percentage of splenic lymphocytes that are CD8+ T cells [%] CD4_neg_CD8_pos_of_tot 63519	CC w/par	65	both	5-8wks	N=2	2018

Lesage1:22	Lesage1	immune cell quantification	(none)	ratio of splenic CD4+ to CD8+ T cells [ratio] CD4_CD8_ratio 63522	CC w/par	65	both	5-8wks	N=2	2018

Petkova1:51	Petkova1	immune cell quantification	(none)	CD8 T cells, as percentage of total lymphocytes [%] CD8_all 24251 6mo 12mo 18mo 24mo	inbred	32	both		N=8	2007

Petkova1:56	Petkova1	immune cell quantification	(none)	CD8 T cells, naive, as percentage of total CD8 T cells [%] CD8_naive 24256 6mo 12mo 18mo 24mo	inbred	32	both		N=8	2007

Petkova1:61	Petkova1	immune cell quantification	(none)	CD8 T cells, central memory, as percentage of total CD8 T cells [%] CD8_mem_central 24261 6mo 12mo 18mo 24mo	inbred	32	both		N=8	2007

Petkova1:66	Petkova1	immune cell quantification	(none)	CD8 T cells, effector memory, as percentage of total CD8 T cells [%] CD8_mem_effector 24266 6mo 12mo 18mo 24mo	inbred	32	both		N=8	2007

Petkova1:71	Petkova1	immune cell quantification	(none)	CD8 T cells, effector, as percentage of total CD8 T cells [%] CD8_effector 24271 6mo 12mo 18mo 24mo	inbred	32	both		N=8	2007

Donahue5

immune cell quantification

(none)

CD8 T cells (percentage of viable WBC) [%] pct_CD8 41412

B6.A consomic w/par

22

both

7wks

N=8

2011

Donahue6

immune cell quantification

(none)

CD8 T cells (percentage of viable WBC) [%] pct_CD8 41511

B6.PWD consomic w/par

28

both

7wks

N=8

2011

Farmer1

immune cell quantification

(none)

percentage of viable CD8⁺ T cells in 150 µl collected blood [%] CD8 11335

QTL population

both

6wks

N=206

2001

Graham1

immune cell quantification

West Nile virus

percentage of CD3+ T cells that are CD8+ in brain, post infection [%] CD8_brain 63345 day 7 day 12 day 21 day 28

CC RIX

5

m

8-10wks

N=3

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD3+ T cells that are CD8+ in spleen, post infection [%] CD8_spleen 63349 day 7 day 12 day 21 day 28

CC RIX

2

m

8-10wks

N=3

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD3+ T cells that are NS4b+ in brain, post infection [%] NS4b_brain 63353 day 7 day 12 day 21 day 28

CC RIX

5

m

8-10wks

N=3

2015

Graham1

immune cell quantification

West Nile virus

percentage of CD3+ T cells that are NS4b+ in spleen, post infection [%] NS4b_spleen 63357 day 7 day 12 day 21 day 28

CC RIX

2

m

8-10wks

N=3

2015

Graham3

immune cell quantification

(none)

percentage of splenic CD3+ T cells that are CD8+ (memory precursor panel) [%] mp_CD3_pos_CD8_pos 113813

CC RIX

92

m

8-10wks

N=4

2021

Graham3

immune cell quantification

(none)

percentage of splenic CD8+ T cells that are CD44+ (memory precursor panel) [%] mp_CD8_pos_CD44_pos 113814

CC RIX

91

m

8-10wks

N=4

2021

Graham3

immune cell quantification

(none)

percentage of splenic CD8+ T cells that are CD62L- (memory precursor panel) [%] mp_CD8_pos_CD62L_neg 113815

CC RIX

76

m

8-10wks

N=3

2021

Graham3

immune cell quantification

(none)

percentage of splenic CD8+ T cells that are Ki67+ (memory precursor panel) [%] mp_CD8_pos_Ki67_pos 113816

CC RIX

92

m

8-10wks

N=4

2021

Graham3

immune cell quantification

(none)

percentage of splenic CD3+ T cells that are CD8+ (memory panel) [%] mem_CD3_pos_CD8_pos 113826

CC RIX

68

m

8-10wks

N=3

2021

Graham3

immune cell quantification

(none)

percentage of splenic CD8+ T cells that are CD44+ (memory panel) [%] mem_CD8_pos_CD44_pos 113827

CC RIX

73

m

8-10wks

N=3

2021

Graham3

immune cell quantification

(none)

percentage of splenic CD8+ T cells that are CD62L- (memory panel) [%] mem_CD8_pos_CD62L_neg 113828

CC RIX

68

m

8-10wks

N=3

2021

Graham3

immune cell quantification

(none)

percentage of splenic CD8+ T cells that are Ki67+ (memory panel) [%] mem_CD8_pos_Ki67_pos 113829

CC RIX

73

m

8-10wks

N=3

2021

Graham3

immune cell quantification

(none)

percentage of splenic CD3+ T cells that are CD8+ following stimulation with anti-CD3 and anti-CD28 [%] ics_CD3_pos_CD8_pos 113839

CC RIX

102

m

8-10wks

N=4

2021

Graham3

immune cell quantification

(none)

percentage of splenic CD8+ T cells that are IL-17+ by intracellular cytokine staining following stimulation with anti-CD3 and anti-CD28 [%] ics_CD8_pos_IL17_pos 113840

CC RIX

102

m

8-10wks

N=4

2021

Graham3

immune cell quantification

(none)

percentage of splenic CD8+ T cells that are IFNg+ by intracellular cytokine staining following stimulation with anti-CD3 and anti-CD28 [%] ics_CD8_pos_IGNg_pos 113841

CC RIX

102

m

8-10wks

N=4

2021

Hackstein1

immune cell quantification

(none)

bronchoalveolar lavage CD3+ CD8+ T cells (percentage of CD45+ cells) [%] T_CD8 49115

inbred

5

m

7-11wks

N=9

2012

Jaxpheno6

immune cell quantification

(none)

splenic CD8 T cells (percentage of total viable cells) [%] pct_CD8 23103 8wks 16wks

inbred

11

both

N=9

2006

Lesage1

immune cell quantification

(none)

percentage of splenic T cells that are CD4- CD8+ [%] CD4_neg_CD8_pos_of_Tcells 63518

CC w/par

65

both

5-8wks

N=2

2018

Lesage1

immune cell quantification

(none)

percentage of splenic lymphocytes that are CD8+ T cells [%] CD4_neg_CD8_pos_of_tot 63519

CC w/par

65

both

5-8wks

N=2

2018

Lesage1

immune cell quantification

(none)

ratio of splenic CD4+ to CD8+ T cells [ratio] CD4_CD8_ratio 63522

CC w/par

65

both

5-8wks

N=2

2018

Petkova1

immune cell quantification

(none)

CD8 T cells, as percentage of total lymphocytes [%] CD8_all 24251 6mo 12mo 18mo 24mo

inbred

32

both

N=8

2007

Petkova1

immune cell quantification

(none)

CD8 T cells, naive, as percentage of total CD8 T cells [%] CD8_naive 24256 6mo 12mo 18mo 24mo

inbred

32

both

N=8

2007

Petkova1

immune cell quantification

(none)

CD8 T cells, central memory, as percentage of total CD8 T cells [%] CD8_mem_central 24261 6mo 12mo 18mo 24mo

inbred

32

both

N=8

2007

Petkova1

immune cell quantification

(none)

CD8 T cells, effector memory, as percentage of total CD8 T cells [%] CD8_mem_effector 24266 6mo 12mo 18mo 24mo

inbred

32

both

N=8

2007

Petkova1

immune cell quantification

(none)

CD8 T cells, effector, as percentage of total CD8 T cells [%] CD8_effector 24271 6mo 12mo 18mo 24mo

inbred

32

both

N=8

2007

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