Project measure / variable:   Graham3   ics_CD8_pos_IGNg_pos

ID, description, units MPD:113841   ics_CD8_pos_IGNg_pos   percentage of splenic CD8+ T cells that are IFNg+ by intracellular cytokine staining following stimulation with anti-CD3 and anti-CD28   [%]  
Data set, strains Graham3   CC RIX   102 strains     sex: m     age: 8-10wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Graham3 - percentage of splenic CD8+ T cells that are IFNg+ by intracellular cytokine staining following stimulation with anti-CD3 and anti-CD28



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested102 strains
Mean of the strain means0.9918   %
Median of the strain means0.23934   %
SD of the strain means± 2.117
Coefficient of variation (CV)2.1345
Min–max range of strain means0.0   –   11.282   %
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 101 2156.1511 21.348 2.5167 < 0.0001
Residuals 358 3036.7908 8.4827


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(001 x 055) m 0.04807 0.01397   6 0.00570238 0.2906 0.0297, 0.0658 -0.45
RIX:CC(001 x 074) m 0.077 0.06669   3 0.0385 0.866 -0.43
RIX:CC(002 x 011) m 1.7568 1.4551   5 0.65073 0.8282 0.36
RIX:CC(002 x 021) m 0.00903333 0.01687   6 0.00688775 1.8677 -0.46
RIX:CC(003 x 051) m 4.0748 3.2708   6 1.3353 0.8027 0.849, 7.85 1.46
RIX:CC(003 x 062) m 4.2893 8.3594   6 3.4127 1.9489 1.56
RIX:CC(004 x 011) m 2.6538 4.1489   6 1.6938 1.5633 0.62, 11.1 0.79
RIX:CC(004 x 012) m 0.85325 1.1404   6 0.46556 1.3365 0.0253, 2.77 -0.07
RIX:CC(005 x 001) m 0.27208 0.16903   6 0.06901 0.6213 0.0355, 0.471 -0.34
RIX:CC(005 x 038) m 0.08153 0.07868   3 0.04542 0.965 -0.43
RIX:CC(005 x 040) m 2.4217 3.1926   6 1.3034 1.3184 0.477, 8.3 0.68
RIX:CC(006 x 007) m 0.4385 0.46984   6 0.19181 1.0715 -0.26
RIX:CC(006 x 039) m 0.09863 0.05215   3 0.03011 0.5287 0.0541, 0.156 -0.42
RIX:CC(007 x 070) m 0.677 0.11049   3 0.06379 0.1632 0.603, 0.804 -0.15
RIX:CC(008 x 009) m 0.383 0.26364   3 0.15221 0.6884 0.206, 0.686 -0.29
RIX:CC(008 x 010) m 0.519 0.46933   3 0.27097 0.9043 0.221, 1.06 -0.22
RIX:CC(008 x 018) m 0.0 0.0   3 0.0 None -0.47
RIX:CC(009 x 040) m 0.66917 0.75692   6 0.30901 1.1311 -0.15
RIX:CC(010 x 015) m 0.09796 0.09667   6 0.03947 0.9869 -0.42
RIX:CC(010 x 060) m 0.09873 0.03061   3 0.01767 0.31 0.0741, 0.133 -0.42
RIX:CC(011 x 032) m 0.37567 0.26635   3 0.15378 0.709 0.212, 0.683 -0.29
RIX:CC(011 x 042) m 0.1219 0.14013   6 0.05721 1.1496 -0.41
RIX:CC(012 x 032) m 0.52264 1.0828   6 0.44205 2.0718 -0.22
RIX:CC(012 x 038) m 0.0549 0.04985   3 0.02878 0.908 0.0157, 0.111 -0.44
RIX:CC(013 x 041) m 0.32372 0.18719   9 0.0624 0.5783 0.0465, 0.63 -0.32
RIX:CC(014 x 059) m 0.0333 0.02467   6 0.01007 0.7408 0.0107, 0.0727 -0.45
RIX:CC(015 x 018) m 9.9493 11.085   6 4.5255 1.1142 0.268, 25.4 4.23
RIX:CC(015 x 059) m 0.04383 0.04307   3 0.02487 0.9826 -0.45
RIX:CC(016 x 038) m 0.23735 0.1922   6 0.07846 0.8098 -0.36
RIX:CC(017 x 004) m 0.416 0.27205   6 0.11107 0.654 0.169, 0.894 -0.27
RIX:CC(017 x 041) m 0.352 0.1442   6 0.05887 0.4097 0.233, 0.613 -0.3
RIX:CC(018 x 009) m 11.282 18.896   3 10.909 1.6749 0.245, 33.1 4.86
RIX:CC(018 x 065) m 0.19567 0.20285   3 0.11711 1.0367 -0.38
RIX:CC(019 x 002) m 0.92261 0.84362   11 0.25436 0.9144 0.0817, 2.29 -0.03
RIX:CC(019 x 004) m 1.2769 1.3964   6 0.57008 1.0936 0.13
RIX:CC(019 x 027) m 0.683 0.19288   3 0.11136 0.2824 0.467, 0.838 -0.15
RIX:CC(021 x 023) m 0.462 0.26154   3 0.151 0.5661 0.31, 0.764 -0.25
RIX:CC(022 x 024) m 7.6067 2.9752   3 1.7177 0.3911 4.65, 10.6 3.12
RIX:CC(022 x 044) m 0.02087 0.03614   3 0.02087 1.7321 -0.46
RIX:CC(023 x 025) m 4.1928 4.7359   6 1.9334 1.1295 1.51
RIX:CC(024 x 023) m 0.05163 0.05045   6 0.02059 0.977 -0.44
RIX:CC(024 x 052) m 0.24133 0.04884   3 0.0282 0.2024 0.202, 0.296 -0.35
RIX:CC(025 x 028) m 0.08758 0.0846   6 0.03454 0.966 -0.43
RIX:CC(026 x 034) m 0.585 1.0564   6 0.43127 1.8058 -0.19
RIX:CC(027 x 036) m 0.0 0.0   3 0.0 None -0.47
RIX:CC(027 x 045) m 2.1433 1.0103   3 0.58328 0.4714 1.12, 3.14 0.54
RIX:CC(029 x 027) m 0.296 0.34101   6 0.13922 1.1521 -0.33
RIX:CC(029 x 071) m 0.0828 0.035   3 0.02021 0.4227 0.0424, 0.104 -0.43
RIX:CC(030 x 023) m 2.1967 0.91216   3 0.52664 0.4152 1.2, 2.99 0.57
RIX:CC(030 x 061) m 0.742 0.59055   6 0.24109 0.7959 0.105, 1.45 -0.12
RIX:CC(032 x 013) m 0.86383 0.36748   6 0.15002 0.4254 0.513, 1.3 -0.06
RIX:CC(032 x 017) m 0.50267 0.13229   6 0.05401 0.2632 0.314, 0.645 -0.23
RIX:CC(033 x 046) m 0.0152 0.03723   6 0.0152 2.4495 -0.46
RIX:CC(035 x 020) m 0.32533 0.14213   3 0.08206 0.4369 0.233, 0.489 -0.31
RIX:CC(035 x 071) m 0.31033 0.07559   3 0.04364 0.2436 0.237, 0.388 -0.32
RIX:CC(036 x 051) m 0.273 0.025   3 0.01443 0.0916 0.248, 0.298 -0.34
RIX:CC(037 x 046) m 0.16833 0.046   3 0.02656 0.2733 0.136, 0.221 -0.39
RIX:CC(037 x 057) m 0.1423 0.07572   6 0.03091 0.5321 0.0395, 0.235 -0.4
RIX:CC(038 x 013) m 0.26315 0.36937   6 0.1508 1.4037 -0.34
RIX:CC(039 x 020) m 1.0327 0.21336   3 0.12318 0.2066 0.788, 1.18 0.02
RIX:CC(040 x 003) m 2.2485 2.2324   6 0.91136 0.9928 0.2, 5.63 0.59
RIX:CC(040 x 015) m 0.1078 0.05515   3 0.03184 0.5116 0.0694, 0.171 -0.42
RIX:CC(041 x 012) m 0.415 0.22601   6 0.09227 0.5446 0.198, 0.702 -0.27
RIX:CC(041 x 016) m 0.06413 0.03178   6 0.01297 0.4955 0.0193, 0.0997 -0.44
RIX:CC(042 x 017) m 0.0745 0.08302   3 0.04793 1.1144 -0.43
RIX:CC(042 x 019) m 7.333 7.466   6 3.048 1.0181 3.0
RIX:CC(043 x 033) m 0.06367 0.11027   3 0.06367 1.7321 -0.44
RIX:CC(043 x 037) m 0.07552 0.06492   6 0.0265 0.8597 0.0314, 0.201 -0.43
RIX:CC(044 x 060) m 0.13447 0.07608   3 0.04392 0.5658 0.0624, 0.214 -0.4
RIX:CC(045 x 044) m 0.0708 0.07109   6 0.02902 1.0041 0.0132, 0.191 -0.44
RIX:CC(046 x 068) m 0.3835 0.20872   6 0.08521 0.5443 0.196, 0.71 -0.29
RIX:CC(049 x 036) m 0.09903 0.02212   3 0.01277 0.2234 0.0794, 0.123 -0.42
RIX:CC(051 x 005) m 0.35259 0.39395   7 0.1489 1.1173 0.044, 1.05 -0.3
RIX:CC(051 x 009) m 0.641 0.29957   6 0.1223 0.4674 0.168, 0.882 -0.17
RIX:CC(052 x 007) m 0.19533 0.09856   3 0.0569 0.5046 0.117, 0.306 -0.38
RIX:CC(052 x 014) m 0.09602 0.04224   5 0.01889 0.4399 0.0567, 0.164 -0.42
RIX:CC(055 x 006) m 0.0125 0.00453961   3 0.00262094 0.3631 0.00931, 0.0177 -0.46
RIX:CC(055 x 028) m 0.90233 0.35297   3 0.20379 0.3912 0.517, 1.21 -0.04
RIX:CC(056 x 033) m 0.20667 0.1607   3 0.09278 0.7776 0.106, 0.392 -0.37
RIX:CC(057 x 052) m 0.14785 0.12214   6 0.04986 0.8261 -0.4
RIX:CC(058 x 022) m 0.18543 0.17361   3 0.10023 0.9362 0.0623, 0.384 -0.38
RIX:CC(059 x 065) m 1.5037 0.91669   6 0.37424 0.6096 0.373, 2.7 0.24
RIX:CC(060 x 006) m 0.07925 0.0628   6 0.02564 0.7924 0.00521, 0.159 -0.43
RIX:CC(060 x 037) m 0.0337 0.01139   3 0.00657673 0.338 0.0213, 0.0437 -0.45
RIX:CC(061 x 025) m 0.03287 0.02873   3 0.01659 0.8741 -0.45
RIX:CC(061 x 026) m 0.11217 0.06762   6 0.02761 0.6029 0.0421, 0.221 -0.42
RIX:CC(061 x 039) m 10.427 11.4   6 4.6542 1.0934 0.024, 22.2 4.46
RIX:CC(062 x 046) m 0.0433 0.02753   3 0.01589 0.6357 0.0211, 0.0741 -0.45
RIX:CC(062 x 072) m 0.15833 0.13929   3 0.08042 0.8797 -0.39
RIX:CC(063 x 001) m 0.1177 0.055   3 0.03175 0.4673 0.0641, 0.174 -0.41
RIX:CC(063 x 002) m 0.22067 0.12208   3 0.07048 0.5532 0.106, 0.349 -0.36
RIX:CC(065 x 010) m 0.10083 0.18429   6 0.07523 1.8276 -0.42
RIX:CC(065 x 072) m 0.51867 0.2165   3 0.12499 0.4174 0.289, 0.719 -0.22
RIX:CC(068 x 035) m 0.0597 0.06326   3 0.03652 1.0596 -0.44
RIX:CC(068 x 043) m 0.357 0.45844   3 0.26468 1.2842 -0.3
RIX:CC(070 x 003) m 0.07423 0.01882   3 0.01087 0.2535 0.0583, 0.095 -0.43
RIX:CC(072 x 063) m 2.1773 2.985   3 1.7234 1.3709 0.56
RIX:CC(072 x 075) m 0.15643 0.06994   3 0.04038 0.4471 0.0923, 0.231 -0.39
RIX:CC(074 x 058) m 1.96 1.1092   3 0.64042 0.5659 1.28, 3.24 0.46
RIX:CC(074 x 062) m 0.0168 0.01886   3 0.01089 1.1226 -0.46
RIX:CC(075 x 021) m 0.1106 0.01111   3 0.00641561 0.1005 0.0998, 0.122 -0.42
RIX:CC(075 x 035) m 0.178 0.15442   3 0.08915 0.8675 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(001 x 055) m 0.0480666667 1.1890231212 2.3864144221 -2.2902810887
RIX:CC(001 x 074) m 0.077 1.681532624 3.3839231092 -3.2299231092
RIX:CC(002 x 011) m 1.7568 1.3025095698 4.3183316259 -0.8047316259
RIX:CC(002 x 021) m 0.0090333333 1.1890231212 2.3473810887 -2.3293144221
RIX:CC(003 x 051) m 4.0748333333 1.1890231212 6.4131810887 1.7364855779
RIX:CC(003 x 062) m 4.2892666667 1.1890231212 6.6276144221 1.9509189113
RIX:CC(004 x 011) m 2.6538333333 1.1890231212 4.9921810887 0.3154855779
RIX:CC(004 x 012) m 0.85325 1.1890231212 3.1915977554 -1.4850977554
RIX:CC(005 x 001) m 0.2720833333 1.1890231212 2.6104310887 -2.0662644221
RIX:CC(005 x 038) m 0.0815333333 1.681532624 3.3884564426 -3.2253897759
RIX:CC(005 x 040) m 2.4216666667 1.1890231212 4.7600144221 0.0833189113
RIX:CC(006 x 007) m 0.4385 1.1890231212 2.7768477554 -1.8998477554
RIX:CC(006 x 039) m 0.0986333333 1.681532624 3.4055564426 -3.2082897759
RIX:CC(007 x 070) m 0.677 1.681532624 3.9839231092 -2.6299231092
RIX:CC(008 x 009) m 0.383 1.681532624 3.6899231092 -2.9239231092
RIX:CC(008 x 010) m 0.519 1.681532624 3.8259231092 -2.7879231092
RIX:CC(008 x 018) m 0.0 1.681532624 3.3069231092 -3.3069231092
RIX:CC(009 x 040) m 0.6691666667 1.1890231212 3.0075144221 -1.6691810887
RIX:CC(010 x 015) m 0.0979566667 1.1890231212 2.4363044221 -2.2403910887
RIX:CC(010 x 060) m 0.0987333333 1.681532624 3.4056564426 -3.2081897759
RIX:CC(011 x 032) m 0.3756666667 1.681532624 3.6825897759 -2.9312564426
RIX:CC(011 x 042) m 0.1219 1.1890231212 2.4602477554 -2.2164477554
RIX:CC(012 x 032) m 0.5226416667 1.1890231212 2.8609894221 -1.8157060887
RIX:CC(012 x 038) m 0.0549 1.681532624 3.3618231092 -3.2520231092
RIX:CC(013 x 041) m 0.3237222222 0.9708333131 2.2329751695 -1.5855307251
RIX:CC(014 x 059) m 0.0333 1.1890231212 2.3716477554 -2.3050477554
RIX:CC(015 x 018) m 9.9493333333 1.1890231212 12.2876810887 7.6109855779
RIX:CC(015 x 059) m 0.0438333333 1.681532624 3.3507564426 -3.2630897759
RIX:CC(016 x 038) m 0.23735 1.1890231212 2.5756977554 -2.1009977554
RIX:CC(017 x 004) m 0.416 1.1890231212 2.7543477554 -1.9223477554
RIX:CC(017 x 041) m 0.352 1.1890231212 2.6903477554 -1.9863477554
RIX:CC(018 x 009) m 11.2816666667 1.681532624 14.5885897759 7.9747435574
RIX:CC(018 x 065) m 0.1956666667 1.681532624 3.5025897759 -3.1112564426
RIX:CC(019 x 002) m 0.9226090909 0.8781517728 2.6495933608 -0.8043751789
RIX:CC(019 x 004) m 1.2769333333 1.1890231212 3.6152810887 -1.0614144221
RIX:CC(019 x 027) m 0.683 1.681532624 3.9899231092 -2.6239231092
RIX:CC(021 x 023) m 0.462 1.681532624 3.7689231092 -2.8449231092
RIX:CC(022 x 024) m 7.6066666667 1.681532624 10.9135897759 4.2997435574
RIX:CC(022 x 044) m 0.0208666667 1.681532624 3.3277897759 -3.2860564426
RIX:CC(023 x 025) m 4.1928333333 1.1890231212 6.5311810887 1.8544855779
RIX:CC(024 x 023) m 0.0516333333 1.1890231212 2.3899810887 -2.2867144221
RIX:CC(024 x 052) m 0.2413333333 1.681532624 3.5482564426 -3.0655897759
RIX:CC(025 x 028) m 0.0875833333 1.1890231212 2.4259310887 -2.2507644221
RIX:CC(026 x 034) m 0.585 1.1890231212 2.9233477554 -1.7533477554
RIX:CC(027 x 036) m 0.0 1.681532624 3.3069231092 -3.3069231092
RIX:CC(027 x 045) m 2.1433333333 1.681532624 5.4502564426 -1.1635897759
RIX:CC(029 x 027) m 0.296 1.1890231212 2.6343477554 -2.0423477554
RIX:CC(029 x 071) m 0.0828 1.681532624 3.3897231092 -3.2241231092
RIX:CC(030 x 023) m 2.1966666667 1.681532624 5.5035897759 -1.1102564426
RIX:CC(030 x 061) m 0.742 1.1890231212 3.0803477554 -1.5963477554
RIX:CC(032 x 013) m 0.8638333333 1.1890231212 3.2021810887 -1.4745144221
RIX:CC(032 x 017) m 0.5026666667 1.1890231212 2.8410144221 -1.8356810887
RIX:CC(033 x 046) m 0.0152 1.1890231212 2.3535477554 -2.3231477554
RIX:CC(035 x 020) m 0.3253333333 1.681532624 3.6322564426 -2.9815897759
RIX:CC(035 x 071) m 0.3103333333 1.681532624 3.6172564426 -2.9965897759
RIX:CC(036 x 051) m 0.273 1.681532624 3.5799231092 -3.0339231092
RIX:CC(037 x 046) m 0.1683333333 1.681532624 3.4752564426 -3.1385897759
RIX:CC(037 x 057) m 0.1423 1.1890231212 2.4806477554 -2.1960477554
RIX:CC(038 x 013) m 0.2631483333 1.1890231212 2.6014960887 -2.0751994221
RIX:CC(039 x 020) m 1.0326666667 1.681532624 4.3395897759 -2.2742564426
RIX:CC(040 x 003) m 2.2485 1.1890231212 4.5868477554 -0.0898477554
RIX:CC(040 x 015) m 0.1078 1.681532624 3.4147231092 -3.1991231092
RIX:CC(041 x 012) m 0.415 1.1890231212 2.7533477554 -1.9233477554
RIX:CC(041 x 016) m 0.0641333333 1.1890231212 2.4024810887 -2.2742144221
RIX:CC(042 x 017) m 0.0745 1.681532624 3.3814231092 -3.2324231092
RIX:CC(042 x 019) m 7.333 1.1890231212 9.6713477554 4.9946522446
RIX:CC(043 x 033) m 0.0636666667 1.681532624 3.3705897759 -3.2432564426
RIX:CC(043 x 037) m 0.0755166667 1.1890231212 2.4138644221 -2.2628310887
RIX:CC(044 x 060) m 0.1344666667 1.681532624 3.4413897759 -3.1724564426
RIX:CC(045 x 044) m 0.0708 1.1890231212 2.4091477554 -2.2675477554
RIX:CC(046 x 068) m 0.3835 1.1890231212 2.7218477554 -1.9548477554
RIX:CC(049 x 036) m 0.0990333333 1.681532624 3.4059564426 -3.2078897759
RIX:CC(051 x 005) m 0.3525857143 1.1008215047 2.5174750665 -1.8123036379
RIX:CC(051 x 009) m 0.641 1.1890231212 2.9793477554 -1.6973477554
RIX:CC(052 x 007) m 0.1953333333 1.681532624 3.5022564426 -3.1115897759
RIX:CC(052 x 014) m 0.09602 1.3025095698 2.6575516259 -2.4655116259
RIX:CC(055 x 006) m 0.0125033333 1.681532624 3.3194264426 -3.2944197759
RIX:CC(055 x 028) m 0.9023333333 1.681532624 4.2092564426 -2.4045897759
RIX:CC(056 x 033) m 0.2066666667 1.681532624 3.5135897759 -3.1002564426
RIX:CC(057 x 052) m 0.14785 1.1890231212 2.4861977554 -2.1904977554
RIX:CC(058 x 022) m 0.1854333333 1.681532624 3.4923564426 -3.1214897759
RIX:CC(059 x 065) m 1.5036666667 1.1890231212 3.8420144221 -0.8346810887
RIX:CC(060 x 006) m 0.0792516667 1.1890231212 2.4175994221 -2.2590960887
RIX:CC(060 x 037) m 0.0337 1.681532624 3.3406231092 -3.2732231092
RIX:CC(061 x 025) m 0.0328666667 1.681532624 3.3397897759 -3.2740564426
RIX:CC(061 x 026) m 0.1121666667 1.1890231212 2.4505144221 -2.2261810887
RIX:CC(061 x 039) m 10.4268333333 1.1890231212 12.7651810887 8.0884855779
RIX:CC(062 x 046) m 0.0433 1.681532624 3.3502231092 -3.2636231092
RIX:CC(062 x 072) m 0.1583333333 1.681532624 3.4652564426 -3.1485897759
RIX:CC(063 x 001) m 0.1177 1.681532624 3.4246231092 -3.1892231092
RIX:CC(063 x 002) m 0.2206666667 1.681532624 3.5275897759 -3.0862564426
RIX:CC(065 x 010) m 0.1008333333 1.1890231212 2.4391810887 -2.2375144221
RIX:CC(065 x 072) m 0.5186666667 1.681532624 3.8255897759 -2.7882564426
RIX:CC(068 x 035) m 0.0597 1.681532624 3.3666231092 -3.2472231092
RIX:CC(068 x 043) m 0.357 1.681532624 3.6639231092 -2.9499231092
RIX:CC(070 x 003) m 0.0742333333 1.681532624 3.3811564426 -3.2326897759
RIX:CC(072 x 063) m 2.1773333333 1.681532624 5.4842564426 -1.1295897759
RIX:CC(072 x 075) m 0.1564333333 1.681532624 3.4633564426 -3.1504897759
RIX:CC(074 x 058) m 1.96 1.681532624 5.2669231092 -1.3469231092
RIX:CC(074 x 062) m 0.0168 1.681532624 3.3237231092 -3.2901231092
RIX:CC(075 x 021) m 0.1106 1.681532624 3.4175231092 -3.1963231092
RIX:CC(075 x 035) m 0.178 1.681532624 3.4849231092 -3.1289231092




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA