Project measure / variable:   Lesage1   CD4_neg_CD8_pos_of_Tcells

ID, description, units MPD:63518   CD4_neg_CD8_pos_of_Tcells   percentage of splenic T cells that are CD4- CD8+   [%]  
Data set, strains Lesage1   CC w/par   76 strains     sex: both     age: 5-8wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Lesage1 - percentage of splenic T cells that are CD4- CD8+



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested46 strains65 strains
Mean of the strain means43.804   % 45.213   %
Median of the strain means42.925   % 41.15   %
SD of the strain means± 10.064 ± 13.015
Coefficient of variation (CV)0.2297 0.2879
Min–max range of strain means20.5   –   64.8   % 18.6   –   71.0   %
Mean sample size per strain2.2   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.5111 2.5111 0.1767 0.6767
strain 12 5530.4454 460.8705 32.4387 < 0.0001
sex:strain 12 311.9124 25.9927 1.8295 0.0802
Residuals 36 511.468 14.2074


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 46.3 4.2426   2   3.0 0.0916 43.3, 49.3 0.25
129S1/SvImJ m 46.15 4.3134   2   3.05 0.0935 43.1, 49.2 0.07
A/J f 43.5 0.42426   2   0.3 0.0098 43.2, 43.8 -0.03
A/J m 40.6 3.677   2   2.6 0.0906 38.0, 43.2 -0.35
C57BL/6J f 51.0 8.9826   4 4.4913 0.1761 38.1, 58.8 0.72
C57BL/6J m 39.5 0.0   1   0.0 0.0 39.5, 39.5 -0.44
CAST/EiJ f 34.8 5.6569   2   4.0 0.1626 30.8, 38.8 -0.89
CAST/EiJ m 31.7 6.7882   2   4.8 0.2141 26.9, 36.5 -1.04
CC008/Geni m 26.467 2.1779   3 1.2574 0.0823 24.7, 28.9 -1.44
CC010/Geni f 48.05 0.35355   2   0.25 0.0074 47.8, 48.3 0.42
CC010/Geni m 46.8 0.0   1   0.0 0.0 46.8, 46.8 0.12
CC012/Geni f 52.7 0.70711   2   0.5 0.0134 52.2, 53.2 0.88
CC012/Geni m 62.17 4.3547   3 2.5142 0.07 57.7, 66.4 1.3
CC013/Geni m 59.73 3.9929   3 2.3053 0.0668 56.9, 64.3 1.12
CC016/Geni m 69.37 1.4048   3 0.81104 0.0203 67.9, 70.7 1.86
CC020/Geni f 30.3 0.0   1   0.0 0.0 30.3, 30.3 -1.34
CC020/Geni m 32.5 1.8385   2   1.3 0.0566 31.2, 33.8 -0.98
CC023/Geni m 32.967 1.3051   3 0.75351 0.0396 31.5, 34.0 -0.94
CC024/Geni f 62.2 0.84853   2   0.6 0.0136 61.6, 62.8 1.83
CC024/Geni m 46.0 0.0   1   0.0 0.0 46.0, 46.0 0.06
CC025/Geni f 45.633 2.4987   3 1.4426 0.0548 42.9, 47.8 0.18
CC026/Geni m 62.53 2.7538   3 1.5899 0.044 60.7, 65.7 1.33
CC027/Geni f 64.8 0.0   1   0.0 0.0 64.8, 64.8 2.09
CC027/Geni m 66.0 2.687   2   1.9 0.0407 64.1, 67.9 1.6
CC030/Geni f 38.2 10.889   2   7.7 0.2851 30.5, 45.9 -0.56
CC031/Geni f 52.6 0.0   1   0.0 0.0 52.6, 52.6 0.87
CC031/Geni m 57.35 3.0406   2   2.15 0.053 55.2, 59.5 0.93
CC032/Geni m 27.8 2.0298   3 1.1719 0.073 25.6, 29.6 -1.34
CC033/Geni f 48.333 2.248   3 1.2979 0.0465 46.4, 50.8 0.45
CC038/Geni f 59.15 3.7477   2   2.65 0.0634 56.5, 61.8 1.52
CC038/Geni m 52.7 0.0   1   0.0 0.0 52.7, 52.7 0.58
CC042/Geni m 35.833 2.3798   3 1.374 0.0664 33.7, 38.4 -0.72
CC043/Geni m 30.7 0.26458   3 0.15275 0.0086 30.5, 31.0 -1.12
CC056/Geni f 41.6 0.0   1   0.0 0.0 41.6, 41.6 -0.22
CC056/Geni m 40.0 0.42426   2   0.3 0.0106 39.7, 40.3 -0.4
CC061/Geni m 62.17 3.6679   3 2.1177 0.059 59.3, 66.3 1.3
CIV2_FE f 36.467 2.8361   3 1.6374 0.0778 33.2, 38.3 -0.73
DET3_GA m 34.7 0.78102   3 0.45092 0.0225 33.8, 35.2 -0.81
DONNELL_HA f 38.8 0.28284   2   0.2 0.0073 38.6, 39.0 -0.5
DONNELL_HA m 36.333 1.193   3 0.6888 0.0328 35.5, 37.7 -0.68
FIV_AC m 61.12 5.5054   4 2.7527 0.0901 56.1, 66.7 1.22
FUF_HE f 30.867 1.0693   3 0.61734 0.0346 30.2, 32.1 -1.29
GALASUPREME_CE m 53.9 1.51   3 0.87178 0.028 52.5, 55.5 0.67
GIT_GC f 35.2 0.0   1   0.0 0.0 35.2, 35.2 -0.85
GIT_GC m 32.55 2.8991   2   2.05 0.0891 30.5, 34.6 -0.97
HAX2_EF f 49.933 0.92376   3 0.53333 0.0185 49.4, 51.0 0.61
HAZ_FE f 35.4 0.0   1   0.0 0.0 35.4, 35.4 -0.84
HAZ_FE m 28.45 1.3435   2   0.95 0.0472 27.5, 29.4 -1.29
HIP_GA f 50.9 0.0   1   0.0 0.0 50.9, 50.9 0.71
HIP_GA m 48.95 1.4849   2   1.05 0.0303 47.9, 50.0 0.29
HOE_GC f 42.3 0.0   1   0.0 0.0 42.3, 42.3 -0.15
HOE_GC m 48.6 0.70711   2   0.5 0.0145 48.1, 49.1 0.26
JUD_EF m 36.1 7.7962   4 3.8981 0.216 28.5, 44.1 -0.7
KAV_AF f 20.5 1.5556   2   1.1 0.0759 19.4, 21.6 -2.32
KAV_AF m 18.6 0.0   1   0.0 0.0 18.6, 18.6 -2.04
LAM_DC f 62.3 0.0   1   0.0 0.0 62.3, 62.3 1.84
LAM_DC m 61.7 0.0   1   0.0 0.0 61.7, 61.7 1.27
LAT_HD f 51.62 2.7216   5 1.2171 0.0527 49.5, 54.6 0.78
LAT_HD m 50.5 4.3841   2   3.1 0.0868 47.4, 53.6 0.41
LAX_FC m 37.85 2.192   2   1.55 0.0579 36.3, 39.4 -0.57
LEL_FH m 39.5 0.84853   2   0.6 0.0215 38.9, 40.1 -0.44
LIP_BG f 42.35 3.0621   4 1.5311 0.0723 38.4, 45.8 -0.14
LIP_BG m 37.4 0.0   1   0.0 0.0 37.4, 37.4 -0.6
LIV_DA f 47.6 0.0   1   0.0 0.0 47.6, 47.6 0.38
LIV_DA m 43.9 3.677   2   2.6 0.0838 41.3, 46.5 -0.1
LOD_AE f 28.833 2.318   3 1.3383 0.0804 27.3, 31.5 -1.49
LOM_BG m 43.033 2.4007   3 1.386 0.0558 40.3, 44.8 -0.17
LOT_FC f 40.867 0.45092   3 0.26034 0.011 40.4, 41.3 -0.29
LOT_FC m 33.95 6.2933   2   4.45 0.1854 29.5, 38.4 -0.87
LOX_GF m 69.7 1.253   3 0.72342 0.018 68.4, 70.9 1.88
LUF_AD m 38.68 16.76   5 7.4952 0.4333 25.3, 59.4 -0.5
LUG_EH m 62.07 1.5177   3 0.87623 0.0245 60.7, 63.7 1.3
LUS_AH f 56.7 1.7436   3 1.0066 0.0308 54.7, 57.9 1.28
LUV_DG m 62.17 5.213   4 2.6065 0.0838 56.8, 68.0 1.3
LUZ_FH f 24.95 4.4548   2   3.15 0.1785 21.8, 28.1 -1.87
LUZ_FH m 24.8 0.0   1   0.0 0.0 24.8, 24.8 -1.57
MERCURI_HF m 71.0 2.1   3 1.2124 0.0296 68.6, 72.5 1.98
NOD/ShiLtJ f 38.95 1.6263   2   1.15 0.0418 37.8, 40.1 -0.48
NOD/ShiLtJ m 41.15 1.3435   2   0.95 0.0326 40.2, 42.1 -0.31
NZO/HlLtJ f 33.75 3.7477   2   2.65 0.111 31.1, 36.4 -1.0
NZO/HlLtJ m 34.25 2.3335   2   1.65 0.0681 32.6, 35.9 -0.84
PAT_CD m 62.67 0.58595   3 0.3383 0.0094 62.0, 63.1 1.34
PEF_EC f 62.3 5.8387   3 3.371 0.0937 57.5, 68.8 1.84
PEF_EC m 68.13 6.1452   3 3.5479 0.0902 62.9, 74.9 1.76
POH_DC f 50.43 4.7248   3 2.7278 0.0937 46.9, 55.8 0.66
PWK/PhJ f 44.9 1.6971   2   1.2 0.0378 43.7, 46.1 0.11
PWK/PhJ m 40.65 4.0305   2   2.85 0.0992 37.8, 43.5 -0.35
SEH_AH f 41.5 0.0   1   0.0 0.0 41.5, 41.5 -0.23
SEH_AH m 43.7 0.0   1   0.0 0.0 43.7, 43.7 -0.12
STUCKY_HF f 40.0 4.7085   3 2.7185 0.1177 34.7, 43.7 -0.38
STUCKY_HF m 37.0 0.0   1   0.0 0.0 37.0, 37.0 -0.63
VIT_ED f 32.533 0.85049   3 0.49103 0.0261 31.7, 33.4 -1.12
VUX2_HF m 32.767 1.4189   3 0.81921 0.0433 31.5, 34.3 -0.96
WAD f 36.233 1.5631   3 0.90247 0.0431 34.8, 37.9 -0.75
WSB/EiJ f 38.6 5.6569   2   4.0 0.1466 34.6, 42.6 -0.52
WSB/EiJ m 39.35 4.5962   2   3.25 0.1168 36.1, 42.6 -0.45
XAD8_BG f 42.3 0.0   1   0.0 0.0 42.3, 42.3 -0.15
XAD8_BG m 39.1 0.65574   3 0.37859 0.0168 38.5, 39.8 -0.47
XAH3_GH m 30.767 1.115   3 0.64377 0.0362 29.5, 31.6 -1.11
XAS4_AF m 54.63 0.60277   3 0.34801 0.011 54.0, 55.2 0.72
XAV_AH m 44.533 3.0989   3 1.7892 0.0696 41.8, 47.9 -0.05
XAW2_CD m 56.4 1.8385   2   1.3 0.0326 55.1, 57.7 0.86
XEB2_AG f 44.633 2.0551   3 1.1865 0.046 43.3, 47.0 0.08
XEB2_AG m 50.43 1.5044   3 0.86859 0.0298 49.0, 52.0 0.4
XEB_AF f 43.8 1.5556   2   1.1 0.0355 42.7, 44.9 0.0
XEB_AF m 41.4 0.0   1   0.0 0.0 41.4, 41.4 -0.29
XEQ_EH m 65.23 0.32146   3 0.18559 0.0049 65.0, 65.6 1.54
XXEN2_DC m 38.533 0.47258   3 0.27285 0.0123 38.0, 38.9 -0.51
XXEN3_DC f 50.3 0.0   1   0.0 0.0 50.3, 50.3 0.65
XXEN3_DC m 39.6 0.0   1   0.0 0.0 39.6, 39.6 -0.43
YOX_DE m 33.967 2.7647   3 1.5962 0.0814 30.8, 35.9 -0.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 46.3 2.6653 51.7054 40.8946
129S1/SvImJ m 46.15 2.6653 51.5554 40.7446
A/J f 43.5 2.6653 48.9054 38.0946
A/J m 40.6 2.6653 46.0054 35.1946
CAST/EiJ f 34.8 2.6653 40.2054 29.3946
CAST/EiJ m 31.7 2.6653 37.1054 26.2946
CC012/Geni f 52.7 2.6653 58.1054 47.2946
CC012/Geni m 62.1667 2.1762 66.5802 57.7531
DONNELL_HA f 38.8 2.6653 44.2054 33.3946
DONNELL_HA m 36.3333 2.1762 40.7469 31.9198
LAT_HD f 51.62 1.6857 55.0387 48.2013
LAT_HD m 50.5 2.6653 55.9054 45.0946
LOT_FC f 40.8667 2.1762 45.2802 36.4531
LOT_FC m 33.95 2.6653 39.3554 28.5446
NOD/ShiLtJ f 38.95 2.6653 44.3554 33.5446
NOD/ShiLtJ m 41.15 2.6653 46.5554 35.7446
NZO/HlLtJ f 33.75 2.6653 39.1554 28.3446
NZO/HlLtJ m 34.25 2.6653 39.6554 28.8446
PEF_EC f 62.3 2.1762 66.7135 57.8865
PEF_EC m 68.1333 2.1762 72.5469 63.7198
PWK/PhJ f 44.9 2.6653 50.3054 39.4946
PWK/PhJ m 40.65 2.6653 46.0554 35.2446
WSB/EiJ f 38.6 2.6653 44.0054 33.1946
WSB/EiJ m 39.35 2.6653 44.7554 33.9446
XEB2_AG f 44.6333 2.1762 49.0469 40.2198
XEB2_AG m 50.4333 2.1762 54.8469 46.0198


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 46.225 1.8846 50.0472 42.4028
A/J both 42.05 1.8846 45.8722 38.2278
CAST/EiJ both 33.25 1.8846 37.0722 29.4278
CC012/Geni both 57.4333 1.7204 60.9225 53.9441
DONNELL_HA both 37.5667 1.7204 41.0559 34.0775
LAT_HD both 51.06 1.5768 54.2579 47.8621
LOT_FC both 37.4083 1.7204 40.8975 33.9191
NOD/ShiLtJ both 40.05 1.8846 43.8722 36.2278
NZO/HlLtJ both 34.0 1.8846 37.8222 30.1778
PEF_EC both 65.2167 1.5388 68.3375 62.0958
PWK/PhJ both 42.775 1.8846 46.5972 38.9528
WSB/EiJ both 38.975 1.8846 42.7972 35.1528
XEB2_AG both 47.5333 1.5388 50.6542 44.4125




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA