Project measure / variable:   Lesage1   CD4_CD8_ratio

ID, description, units MPD:63522   CD4_CD8_ratio   ratio of splenic CD4+ to CD8+ T cells   [ratio]  
Data set, strains Lesage1   CC w/par   76 strains     sex: both     age: 5-8wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Lesage1 - ratio of splenic CD4+ to CD8+ T cells



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested46 strains65 strains
Mean of the strain means1.2754   ratio 1.237   ratio
Median of the strain means1.1885   ratio 1.2807   ratio
SD of the strain means± 0.63065 ± 0.69034
Coefficient of variation (CV)0.4945 0.5581
Min–max range of strain means0.373   –   3.4995   ratio 0.24667   –   3.952   ratio
Mean sample size per strain2.2   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0563 0.0563 1.0818 0.3052
strain 12 13.4554 1.1213 21.5517 < 0.0001
sex:strain 12 0.6616 0.0551 1.0596 0.4203
Residuals 36 1.873 0.052


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.079 0.17536   2   0.124 0.1625 0.955, 1.203 -0.31
129S1/SvImJ m 1.1155 0.19163   2   0.1355 0.1718 0.98, 1.251 -0.18
A/J f 1.208 0.01697   2   0.012 0.014 1.196, 1.22 -0.11
A/J m 1.3795 0.24537   2   0.1735 0.1779 1.206, 1.553 0.21
C57BL/6J f 0.91825 0.41472   4 0.20736 0.4516 0.624, 1.533 -0.57
C57BL/6J m 1.471 0.0   1   0.0 0.0 1.471, 1.471 0.34
CAST/EiJ f 1.7985 0.4872   2   0.3445 0.2709 1.454, 2.143 0.83
CAST/EiJ m 2.062 0.75378   2   0.533 0.3656 1.529, 2.595 1.2
CC008/Geni m 2.509 0.16731   3 0.0966 0.0667 2.325, 2.652 1.84
CC010/Geni f 0.9885 0.01344   2   0.0095 0.0136 0.979, 0.998 -0.45
CC010/Geni m 1.075 0.0   1   0.0 0.0 1.075, 1.075 -0.23
CC012/Geni f 0.7375 0.02475   2   0.0175 0.0336 0.72, 0.755 -0.85
CC012/Geni m 0.45167 0.07012   3 0.04048 0.1552 0.372, 0.504 -1.14
CC013/Geni m 0.46767 0.09182   3 0.05301 0.1963 0.362, 0.528 -1.11
CC016/Geni m 0.30367 0.01242   3 0.00717248 0.0409 0.296, 0.318 -1.35
CC020/Geni f 2.158 0.0   1   0.0 0.0 2.158, 2.158 1.4
CC020/Geni m 1.871 0.12304   2   0.087 0.0658 1.784, 1.958 0.92
CC023/Geni m 1.4467 0.109   3 0.06293 0.0753 1.338, 1.556 0.3
CC024/Geni f 0.529 0.00989949   2   0.007 0.0187 0.522, 0.536 -1.18
CC024/Geni m 0.987 0.0   1   0.0 0.0 0.987, 0.987 -0.36
CC025/Geni f 1.13 0.12287   3 0.07094 0.1087 1.027, 1.266 -0.23
CC026/Geni m 0.481 0.05603   3 0.03235 0.1165 0.426, 0.538 -1.1
CC027/Geni f 0.373 0.0   1   0.0 0.0 0.373, 0.373 -1.43
CC027/Geni m 0.376 0.05233   2   0.037 0.1392 0.339, 0.413 -1.25
CC030/Geni f 1.3645 0.63003   2   0.4455 0.4617 0.919, 1.81 0.14
CC031/Geni f 0.648 0.0   1   0.0 0.0 0.648, 0.648 -0.99
CC031/Geni m 0.5325 0.08273   2   0.0585 0.1554 0.474, 0.591 -1.02
CC032/Geni m 2.2513 0.28195   3 0.16278 0.1252 2.014, 2.563 1.47
CC033/Geni f 0.795 0.06154   3 0.03553 0.0774 0.728, 0.849 -0.76
CC038/Geni f 0.6175 0.12233   2   0.0865 0.1981 0.531, 0.704 -1.04
CC038/Geni m 0.822 0.0   1   0.0 0.0 0.822, 0.822 -0.6
CC042/Geni m 1.606 0.18007   3 0.10396 0.1121 1.411, 1.766 0.53
CC043/Geni m 2.0947 0.05424   3 0.03132 0.0259 2.035, 2.141 1.24
CC056/Geni f 1.325 0.0   1   0.0 0.0 1.325, 1.325 0.08
CC056/Geni m 1.394 0.00565685   2   0.004 0.0041 1.39, 1.398 0.23
CC061/Geni m 0.53233 0.09445   3 0.05453 0.1774 0.428, 0.612 -1.02
CIV2_FE f 1.5983 0.19117   3 0.11037 0.1196 1.483, 1.819 0.51
DET3_GA m 1.7617 0.06552   3 0.03783 0.0372 1.718, 1.837 0.76
DONNELL_HA f 1.4705 0.00919239   2   0.0065 0.0063 1.464, 1.477 0.31
DONNELL_HA m 1.6017 0.03175   3 0.01833 0.0198 1.565, 1.62 0.53
FIV_AC m 0.5895 0.15003   4 0.07502 0.2545 0.444, 0.733 -0.94
FUF_HE f 2.023 0.10206   3 0.05892 0.0504 1.907, 2.099 1.19
GALASUPREME_CE m 0.70867 0.06888   3 0.03977 0.0972 0.636, 0.773 -0.77
GIT_GC f 1.591 0.0   1   0.0 0.0 1.591, 1.591 0.5
GIT_GC m 1.815 0.26163   2   0.185 0.1441 1.63, 2.0 0.84
HAX2_EF f 0.69633 0.01305   3 0.0075351 0.0187 0.686, 0.711 -0.92
HAZ_FE f 1.605 0.0   1   0.0 0.0 1.605, 1.605 0.52
HAZ_FE m 2.284 0.11738   2   0.083 0.0514 2.201, 2.367 1.52
HIP_GA f 0.862 0.0   1   0.0 0.0 0.862, 0.862 -0.66
HIP_GA m 0.908 0.04808   2   0.034 0.053 0.874, 0.942 -0.48
HOE_GC f 1.13 0.0   1   0.0 0.0 1.13, 1.13 -0.23
HOE_GC m 0.922 0.00424264   2   0.003 0.0046 0.919, 0.925 -0.46
JUD_EF m 1.4165 0.50929   4 0.25465 0.3595 0.916, 1.954 0.26
KAV_AF f 3.4995 0.37265   2   0.2635 0.1065 3.236, 3.763 3.53
KAV_AF m 3.952 0.0   1   0.0 0.0 3.952, 3.952 3.93
LAM_DC f 0.544 0.0   1   0.0 0.0 0.544, 0.544 -1.16
LAM_DC m 0.561 0.0   1   0.0 0.0 0.561, 0.561 -0.98
LAT_HD f 0.7112 0.09003   5 0.04026 0.1266 0.597, 0.796 -0.89
LAT_HD m 0.808 0.14284   2   0.101 0.1768 0.707, 0.909 -0.62
LAX_FC m 1.341 0.10182   2   0.072 0.0759 1.269, 1.413 0.15
LEL_FH m 1.3695 0.08839   2   0.0625 0.0645 1.307, 1.432 0.19
LIP_BG f 1.2843 0.19303   4 0.09651 0.1503 1.087, 1.542 0.01
LIP_BG m 1.532 0.0   1   0.0 0.0 1.532, 1.532 0.43
LIV_DA f 1.019 0.0   1   0.0 0.0 1.019, 1.019 -0.41
LIV_DA m 1.1485 0.17324   2   0.1225 0.1508 1.026, 1.271 -0.13
LOD_AE f 2.2943 0.25208   3 0.14554 0.1099 2.006, 2.473 1.62
LOM_BG m 1.2403 0.11398   3 0.0658 0.0919 1.156, 1.37 0.0
LOT_FC f 1.2907 0.03758   3 0.0217 0.0291 1.249, 1.322 0.02
LOT_FC m 1.794 0.62225   2   0.44 0.3469 1.354, 2.234 0.81
LOX_GF m 0.36867 0.02434   3 0.01405 0.066 0.347, 0.395 -1.26
LUF_AD m 1.7104 1.09   5 0.48747 0.6373 0.513, 2.66 0.69
LUG_EH m 0.49167 0.03356   3 0.01938 0.0683 0.457, 0.524 -1.08
LUS_AH f 0.57233 0.04588   3 0.02649 0.0802 0.541, 0.625 -1.11
LUV_DG m 0.4865 0.1464   4 0.0732 0.3009 0.35, 0.657 -1.09
LUZ_FH f 2.9625 0.70216   2   0.4965 0.237 2.466, 3.459 2.68
LUZ_FH m 2.835 0.0   1   0.0 0.0 2.835, 2.835 2.31
MERCURI_HF m 0.24667 0.04484   3 0.02589 0.1818 0.211, 0.297 -1.43
NOD/ShiLtJ f 1.4955 0.12233   2   0.0865 0.0818 1.409, 1.582 0.35
NOD/ShiLtJ m 1.357 0.06081   2   0.043 0.0448 1.314, 1.4 0.17
NZO/HlLtJ f 1.879 0.2984   2   0.211 0.1588 1.668, 2.09 0.96
NZO/HlLtJ m 1.8365 0.1789   2   0.1265 0.0974 1.71, 1.963 0.87
PAT_CD m 0.442 0.01277   3 0.00737111 0.0289 0.431, 0.456 -1.15
PEF_EC f 0.41633 0.11637   3 0.06719 0.2795 0.288, 0.515 -1.36
PEF_EC m 0.30667 0.09457   3 0.0546 0.3084 0.21, 0.399 -1.35
POH_DC f 0.87767 0.18561   3 0.10716 0.2115 0.668, 1.021 -0.63
PWK/PhJ f 1.1185 0.08132   2   0.0575 0.0727 1.061, 1.176 -0.25
PWK/PhJ m 1.3425 0.23405   2   0.1655 0.1743 1.177, 1.508 0.15
SEH_AH f 1.32 0.0   1   0.0 0.0 1.32, 1.32 0.07
SEH_AH m 1.167 0.0   1   0.0 0.0 1.167, 1.167 -0.1
STUCKY_HF f 1.3297 0.37642   3 0.21733 0.2831 1.098, 1.764 0.09
STUCKY_HF m 1.586 0.0   1   0.0 0.0 1.586, 1.586 0.51
VIT_ED f 1.9303 0.0676   3 0.03903 0.035 1.865, 2.0 1.04
VUX2_HF m 1.9033 0.1365   3 0.07881 0.0717 1.81, 2.06 0.97
WAD f 1.603 0.1126   3 0.06501 0.0702 1.48, 1.701 0.52
WSB/EiJ f 1.5415 0.36699   2   0.2595 0.2381 1.282, 1.801 0.42
WSB/EiJ m 1.4715 0.26517   2   0.1875 0.1802 1.284, 1.659 0.34
XAD8_BG f 1.177 0.0   1   0.0 0.0 1.177, 1.177 -0.16
XAD8_BG m 1.2807 0.0595   3 0.03435 0.0465 1.221, 1.34 0.06
XAH3_GH m 1.7163 0.18785   3 0.10846 0.1095 1.573, 1.929 0.69
XAS4_AF m 0.69333 0.0215   3 0.01241 0.031 0.672, 0.715 -0.79
XAV_AH m 1.053 0.10857   3 0.06268 0.1031 0.931, 1.139 -0.27
XAW2_CD m 0.6975 0.03323   2   0.0235 0.0476 0.674, 0.721 -0.78
XEB2_AG f 1.085 0.1025   3 0.05918 0.0945 0.968, 1.159 -0.3
XEB2_AG m 0.899 0.07749   3 0.04474 0.0862 0.817, 0.971 -0.49
XEB_AF f 1.2 0.06223   2   0.044 0.0519 1.156, 1.244 -0.12
XEB_AF m 1.316 0.0   1   0.0 0.0 1.316, 1.316 0.11
XEQ_EH m 0.42833 0.01677   3 0.00968389 0.0392 0.409, 0.439 -1.17
XXEN2_DC m 1.4587 0.03403   3 0.01965 0.0233 1.432, 1.497 0.32
XXEN3_DC f 0.871 0.0   1   0.0 0.0 0.871, 0.871 -0.64
XXEN3_DC m 1.318 0.0   1   0.0 0.0 1.318, 1.318 0.12
YOX_DE m 1.0127 0.23873   3 0.13783 0.2357 0.737, 1.151 -0.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.079 0.1613 1.4061 0.7519
129S1/SvImJ m 1.1155 0.1613 1.4426 0.7884
A/J f 1.208 0.1613 1.5351 0.8809
A/J m 1.3795 0.1613 1.7066 1.0524
CAST/EiJ f 1.7985 0.1613 2.1256 1.4714
CAST/EiJ m 2.062 0.1613 2.3891 1.7349
CC012/Geni f 0.7375 0.1613 1.0646 0.4104
CC012/Geni m 0.4517 0.1317 0.7187 0.1846
DONNELL_HA f 1.4705 0.1613 1.7976 1.1434
DONNELL_HA m 1.6017 0.1317 1.8687 1.3346
LAT_HD f 0.7112 0.102 0.9181 0.5043
LAT_HD m 0.808 0.1613 1.1351 0.4809
LOT_FC f 1.2907 0.1317 1.5577 1.0236
LOT_FC m 1.794 0.1613 2.1211 1.4669
NOD/ShiLtJ f 1.4955 0.1613 1.8226 1.1684
NOD/ShiLtJ m 1.357 0.1613 1.6841 1.0299
NZO/HlLtJ f 1.879 0.1613 2.2061 1.5519
NZO/HlLtJ m 1.8365 0.1613 2.1636 1.5094
PEF_EC f 0.4163 0.1317 0.6834 0.1493
PEF_EC m 0.3067 0.1317 0.5737 0.0396
PWK/PhJ f 1.1185 0.1613 1.4456 0.7914
PWK/PhJ m 1.3425 0.1613 1.6696 1.0154
WSB/EiJ f 1.5415 0.1613 1.8686 1.2144
WSB/EiJ m 1.4715 0.1613 1.7986 1.1444
XEB2_AG f 1.085 0.1317 1.3521 0.8179
XEB2_AG m 0.899 0.1317 1.1661 0.6319


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.0973 0.114 1.3285 0.866
A/J both 1.2938 0.114 1.525 1.0625
CAST/EiJ both 1.9303 0.114 2.1615 1.699
CC012/Geni both 0.5946 0.1041 0.8057 0.3834
DONNELL_HA both 1.5361 0.1041 1.7472 1.3249
LAT_HD both 0.7596 0.0954 0.9531 0.5661
LOT_FC both 1.5423 0.1041 1.7535 1.3312
NOD/ShiLtJ both 1.4263 0.114 1.6575 1.195
NZO/HlLtJ both 1.8578 0.114 2.089 1.6265
PEF_EC both 0.3615 0.0931 0.5504 0.1726
PWK/PhJ both 1.2305 0.114 1.4618 0.9992
WSB/EiJ both 1.5065 0.114 1.7378 1.2752
XEB2_AG both 0.992 0.0931 1.1809 0.8031




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA