Phenotype measure:   Donahue6   pct_CD8

ID, description, units MPD:41511   pct_CD8   CD8 T cells (percentage of viable WBC)   [%]
Data set, strains Donahue6   B6.PWD consomic w/par   28 strains     sex: both     age: 7wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue6 - CD8 T cells (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains28 strains
Mean of the strain means9.58   % 8.35   %
Median of the strain means9.24   % 8.45   %
SD of the strain means± 2.11 ± 2.22
Coefficient of variation (CV)0.220 0.266
Min–max range of strain means6.27   –   13.6   % 2.13   –   13.1   %
Mean sample size per strain8.3   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 157.9338 157.9338 30.5556 < 0.0001
strain 27 1847.3814 68.4215 13.2376 < 0.0001
sex:strain 27 263.3086 9.7522 1.8868 0.0052
Residuals 419 2165.6992 5.1687


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.PWD-Chr1 f 9.36 2.5   8 0.885 0.267 6.57, 13.3 -0.1
B6.PWD-Chr1 m 9.17 1.79   8 0.633 0.195 6.19, 12.1 0.37
B6.PWD-Chr10.1 f 9.12 2.57   11 0.775 0.282 5.53, 12.4 -0.22
B6.PWD-Chr10.1 m 7.67 2.78   8 0.984 0.363 4.55, 12.4 -0.31
B6.PWD-Chr10.2 f 13.0 5.02   8 1.77 0.387 7.0, 18.7 1.62
B6.PWD-Chr10.2 m 6.73 0.847   8 0.3 0.126 5.44, 7.95 -0.73
B6.PWD-Chr10.3 f 12.3 5.69   8 2.01 0.462 6.37, 21.6 1.29
B6.PWD-Chr10.3 m 10.0 3.22   8 1.14 0.322 2.39, 12.5 0.74
B6.PWD-Chr11.1 f 9.11 1.83   12 0.528 0.201 6.61, 12.9 -0.22
B6.PWD-Chr11.1 m 8.56 1.77   12 0.512 0.207 5.97, 12.3 0.09
B6.PWD-Chr11.2 f 11.2 3.59   9 1.2 0.32 5.07, 15.5 0.77
B6.PWD-Chr11.2 m 11.3 3.58   10 1.13 0.317 5.55, 16.1 1.33
B6.PWD-Chr11.3 f 13.6 2.81   8 0.993 0.206 9.05, 17.6 1.91
B6.PWD-Chr11.3 m 13.1 1.55   10 0.489 0.118 10.8, 16.6 2.14
B6.PWD-Chr12 f 10.8 0.741   8 0.262 0.0686 9.85, 12.0 0.58
B6.PWD-Chr12 m 10.0 0.89   8 0.315 0.0888 9.06, 11.7 0.74
B6.PWD-Chr13 f 6.36 0.982   8 0.347 0.154 5.03, 7.72 -1.53
B6.PWD-Chr13 m 5.33 0.835   9 0.278 0.157 4.17, 6.44 -1.36
B6.PWD-Chr14 f 7.24 2.46   8 0.87 0.34 2.05, 9.21 -1.11
B6.PWD-Chr14 m 7.47 0.67   10 0.212 0.0896 6.31, 8.37 -0.4
B6.PWD-Chr15 f 8.59 2.12   7 0.802 0.247 5.76, 11.3 -0.47
B6.PWD-Chr15 m 6.95 1.82   8 0.642 0.261 3.84, 9.77 -0.63
B6.PWD-Chr16 f 7.83 3.06   8 1.08 0.39 2.95, 11.0 -0.83
B6.PWD-Chr16 m 8.77 2.0   8 0.709 0.228 4.73, 10.7 0.19
B6.PWD-Chr17 f 9.06 0.795   8 0.281 0.0877 7.61, 10.3 -0.25
B6.PWD-Chr17 m 6.81 4.47   8 1.58 0.656 1.81, 13.7 -0.69
B6.PWD-Chr18 f 6.27 1.25   8 0.442 0.2 4.54, 8.59 -1.57
B6.PWD-Chr18 m 6.24 0.787   8 0.278 0.126 5.28, 7.19 -0.95
B6.PWD-Chr19 f 10.4 1.91   8 0.676 0.184 7.44, 14.0 0.39
B6.PWD-Chr19 m 10.2 1.15   7 0.436 0.113 7.98, 11.5 0.83
B6.PWD-Chr2 f 6.46 1.6   10 0.506 0.248 4.26, 8.98 -1.48
B6.PWD-Chr2 m 6.0 2.27   8 0.801 0.377 1.95, 8.54 -1.06
B6.PWD-Chr3 f 13.2 1.69   8 0.597 0.128 9.16, 14.3 1.72
B6.PWD-Chr3 m 11.8 1.8   8 0.637 0.153 8.66, 14.5 1.55
B6.PWD-Chr5 f 9.86 2.26   8 0.799 0.229 7.2, 13.9 0.13
B6.PWD-Chr5 m 7.16 2.4   8 0.848 0.335 1.64, 9.37 -0.54
B6.PWD-Chr6 f 6.71 4.1   8 1.45 0.611 1.49, 12.2 -1.36
B6.PWD-Chr6 m 2.13 1.2   8 0.425 0.565 0.72, 4.57 -2.8
B6.PWD-Chr8 f 7.8 1.07   5 0.477 0.137 6.01, 8.87 -0.84
B6.PWD-Chr8 m 7.21 1.42   5 0.635 0.197 5.92, 9.05 -0.51
B6.PWD-Chr9 f 10.3 3.14   8 1.11 0.304 2.87, 12.5 0.34
B6.PWD-Chr9 m 10.6 2.27   8 0.804 0.214 5.79, 13.8 1.01
B6.PWD-ChrX.1 f 8.9 2.86   8 1.01 0.321 2.81, 12.1 -0.32
B6.PWD-ChrX.1 m 9.25 0.829   7 0.313 0.0897 8.01, 10.2 0.4
B6.PWD-ChrX.2 f 9.11 1.01   8 0.356 0.11 7.69, 10.9 -0.22
B6.PWD-ChrX.2 m 7.26 2.37   9 0.79 0.326 4.3, 11.1 -0.49
B6.PWD-ChrX.3 f 9.82 1.45   8 0.512 0.147 8.05, 12.7 0.11
B6.PWD-ChrX.3 m 9.32 0.639   8 0.226 0.0686 8.41, 10.2 0.44
B6.PWD-ChrY f 10.6 1.07   8 0.378 0.101 8.95, 11.8 0.48
B6.PWD-ChrY m 8.33 1.14   8 0.403 0.137 6.98, 10.4 -0.01
B6.PWD-mt f 9.48 2.33   7 0.881 0.246 6.76, 12.9 -0.05
B6.PWD-mt m 8.88 0.751   8 0.266 0.0846 7.86, 10.0 0.24
C57BL/6J f 8.81 1.85   16 0.462 0.21 6.17, 12.1 -0.36
C57BL/6J m 7.64 1.38   16 0.346 0.181 4.33, 9.21 -0.32
PWD/PhJ f 12.9 1.25   7 0.472 0.0969 11.3, 15.1 1.58
PWD/PhJ m 10.0 2.09   8 0.74 0.209 5.83, 12.5 0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 f 9.3587 0.8038 10.9387 7.7788
B6.PWD-Chr1 m 9.17 0.8038 10.75 7.59
B6.PWD-Chr10.1 f 9.1191 0.6855 10.4665 7.7717
B6.PWD-Chr10.1 m 7.6725 0.8038 9.2525 6.0925
B6.PWD-Chr10.2 f 12.9687 0.8038 14.5487 11.3888
B6.PWD-Chr10.2 m 6.7263 0.8038 8.3062 5.1463
B6.PWD-Chr10.3 f 12.3325 0.8038 13.9125 10.7525
B6.PWD-Chr10.3 m 9.9963 0.8038 11.5762 8.4163
B6.PWD-Chr11.1 f 9.1067 0.6563 10.3967 7.8166
B6.PWD-Chr11.1 m 8.5592 0.6563 9.8492 7.2691
B6.PWD-Chr11.2 f 11.1933 0.7578 12.683 9.7037
B6.PWD-Chr11.2 m 11.3 0.7189 12.7132 9.8868
B6.PWD-Chr11.3 f 13.6313 0.8038 15.2112 12.0513
B6.PWD-Chr11.3 m 13.14 0.7189 14.5532 11.7268
B6.PWD-Chr12 f 10.81 0.8038 12.39 9.23
B6.PWD-Chr12 m 10.0325 0.8038 11.6125 8.4525
B6.PWD-Chr13 f 6.36 0.8038 7.94 4.78
B6.PWD-Chr13 m 5.3256 0.7578 6.8152 3.8359
B6.PWD-Chr14 f 7.2413 0.8038 8.8212 5.6613
B6.PWD-Chr14 m 7.475 0.7189 8.8882 6.0618
B6.PWD-Chr15 f 8.5914 0.8593 10.2805 6.9024
B6.PWD-Chr15 m 6.945 0.8038 8.525 5.365
B6.PWD-Chr16 f 7.835 0.8038 9.415 6.255
B6.PWD-Chr16 m 8.7738 0.8038 10.3537 7.1938
B6.PWD-Chr17 f 9.0612 0.8038 10.6412 7.4813
B6.PWD-Chr17 m 6.8125 0.8038 8.3925 5.2325
B6.PWD-Chr18 f 6.2675 0.8038 7.8475 4.6875
B6.PWD-Chr18 m 6.2362 0.8038 7.8162 4.6563
B6.PWD-Chr19 f 10.3713 0.8038 11.9512 8.7913
B6.PWD-Chr19 m 10.1986 0.8593 11.8876 8.5095
B6.PWD-Chr2 f 6.456 0.7189 7.8692 5.0428
B6.PWD-Chr2 m 6.005 0.8038 7.585 4.425
B6.PWD-Chr3 f 13.22 0.8038 14.8 11.64
B6.PWD-Chr3 m 11.8075 0.8038 13.3875 10.2275
B6.PWD-Chr5 f 9.8588 0.8038 11.4387 8.2788
B6.PWD-Chr5 m 7.1588 0.8038 8.7387 5.5788
B6.PWD-Chr6 f 6.71 0.8038 8.29 5.13
B6.PWD-Chr6 m 2.1275 0.8038 3.7075 0.5475
B6.PWD-Chr8 f 7.8 1.0167 9.7985 5.8015
B6.PWD-Chr8 m 7.21 1.0167 9.2085 5.2115
B6.PWD-Chr9 f 10.3213 0.8038 11.9012 8.7413
B6.PWD-Chr9 m 10.6288 0.8038 12.2087 9.0488
B6.PWD-ChrX.1 f 8.9038 0.8038 10.4837 7.3238
B6.PWD-ChrX.1 m 9.2471 0.8593 10.9362 7.5581
B6.PWD-ChrX.2 f 9.11 0.8038 10.69 7.53
B6.PWD-ChrX.2 m 7.2633 0.7578 8.753 5.7737
B6.PWD-ChrX.3 f 9.82 0.8038 11.4 8.24
B6.PWD-ChrX.3 m 9.32 0.8038 10.9 7.74
B6.PWD-ChrY f 10.6213 0.8038 12.2012 9.0413
B6.PWD-ChrY m 8.33 0.8038 9.91 6.75
B6.PWD-mt f 9.48 0.8593 11.1691 7.7909
B6.PWD-mt m 8.8813 0.8038 10.4612 7.3013
C57BL/6J f 8.8063 0.5684 9.9235 7.689
C57BL/6J m 7.6425 0.5684 8.7597 6.5253
PWD/PhJ f 12.8857 0.8593 14.5748 11.1966
PWD/PhJ m 10.035 0.8038 11.615 8.455


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.PWD-Chr1 both 9.2644 0.5684 10.3816 8.1472
B6.PWD-Chr10.1 both 8.3958 0.5282 9.434 7.3575
B6.PWD-Chr10.2 both 9.8475 0.5684 10.9647 8.7303
B6.PWD-Chr10.3 both 11.1644 0.5684 12.2816 10.0472
B6.PWD-Chr11.1 both 8.8329 0.4641 9.7451 7.9207
B6.PWD-Chr11.2 both 11.2467 0.5223 12.2733 10.22
B6.PWD-Chr11.3 both 13.3856 0.5392 14.4455 12.3257
B6.PWD-Chr12 both 10.4213 0.5684 11.5385 9.304
B6.PWD-Chr13 both 5.8428 0.5524 6.9285 4.757
B6.PWD-Chr14 both 7.3581 0.5392 8.418 6.2982
B6.PWD-Chr15 both 7.7682 0.5883 8.9246 6.6118
B6.PWD-Chr16 both 8.3044 0.5684 9.4216 7.1872
B6.PWD-Chr17 both 7.9369 0.5684 9.0541 6.8197
B6.PWD-Chr18 both 6.2519 0.5684 7.3691 5.1347
B6.PWD-Chr19 both 10.2849 0.5883 11.4413 9.1285
B6.PWD-Chr2 both 6.2305 0.5392 7.2904 5.1706
B6.PWD-Chr3 both 12.5138 0.5684 13.631 11.3965
B6.PWD-Chr5 both 8.5088 0.5684 9.626 7.3915
B6.PWD-Chr6 both 4.4188 0.5684 5.536 3.3015
B6.PWD-Chr8 both 7.505 0.7189 8.9182 6.0918
B6.PWD-Chr9 both 10.475 0.5684 11.5922 9.3578
B6.PWD-ChrX.1 both 9.0754 0.5883 10.2319 7.919
B6.PWD-ChrX.2 both 8.1867 0.5524 9.2724 7.1009
B6.PWD-ChrX.3 both 9.57 0.5684 10.6872 8.4528
B6.PWD-ChrY both 9.4756 0.5684 10.5928 8.3584
B6.PWD-mt both 9.1806 0.5883 10.3371 8.0242
C57BL/6J both 8.2244 0.4019 9.0144 7.4344
PWD/PhJ both 11.4604 0.5883 12.6168 10.3039




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA