Wahlsten2: Wildness in 21 inbred strains of mice assessed through a rating scale (2003)

Wahlsten D, Metten P, Crabbe JC. A rating scale for wildness and ease of handling laboratory mice: results for 21 inbred strains tested in two laboratories. Genes Brain Behav. 2003 Apr;2(2):71-9.   PubMed 12884964  


         
Rating scales for difficulty in capturing and holding mice were devised to provide an impression of the difficulties encountered in working with various strains of mice.
This study was conducted on the same set of mice tested for several behavioral parameters and examined for brain defects (Wahlsten1).
Missing data code clarifications:
DI = died; always occurred in home cage in colony room, never during the actual test
ND = no data; almost always occurred because technician failed to record rating
PP = physical problem; for strain C58/J, trial was stopped when they sank in water maze
OT = other; average undefined because of missing values

Procedures conducted:
• behavior observation  Wildness scoring during various phenotyping tests.

Wahlsten2 downloads
• Download Wahlsten2 project data set     animal data, as uploaded
• Download Wahlsten2 animal data matrix     with factor-related expansion applied as necessary
• Download Wahlsten2 strain means, SD, N, etc.     one row per strain/sex/measure
• Wahlsten2 supplementary data
Investigators Douglas Wahlsten       University of Windsor,  Windsor, Ontario CANADA
John C Crabbe       Oregon Health & Science University,  Portland, OR
Pamela Metten       Oregon Health & Science University,  Portland, OR
Participants Bryden C, Moisan B, Cooper SF, Schlumbohm J, Yu C-H
ContactDouglas Wahlsten     dlwahlst@uncg.edu
AcknowledgementsFunding provided by NIH AA12714, AA10760; Department of Veterans Affairs; Natural Sciences and Engineering Research Council of Canada (NSERC 45825)

Generous funds from AstraZeneca were used to defray the cost of mice through the Mouse Phenome Project Collaborations Program.
Project type Phenotype strain survey data set
MPD identifiersWahlsten2     MPD:160
Data changelog No updates/corrections.       Initial release date: 03/2004.
Formatted citation
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Mice: inbred   21 strains   ♀♂   age 10-12wks   1 experimental group

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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
    Wahlsten2 behavior observation (none) number of tests with squeaks   [score]  nsqueak   16001 inbred 21 both 10-12wks N=10
    Wahlsten2 behavior observation (none) number of tests with bites   [score]  nbite   16002 inbred 21 both 10-12wks N=10
    Wahlsten2 behavior observation (none) number of tests with escapes   [score]  nflee   16003 inbred 21 both 10-12wks N=10
    Wahlsten2 behavior observation (none) number of placid tests, capture ratings + hold ratings   [score]  nplacid   16004 inbred 21 both 10-12wks N=10
    Wahlsten2 behavior observation (none) capture rating, overall mean   [score]  capture   16005 inbred 21 both 10-12wks N=8
    Wahlsten2 behavior observation (none) hold rating, overall mean   [score]  hold   16006 inbred 21 both 10-12wks N=8
    Wahlsten2 behavior observation (none) wildness rating, sum of capture and hold means   [score]  wildness   16007 inbred 21 both 10-12wks N=8
    Wahlsten2 behavior observation (none) wildness rating, mean during open field and elevated plus maze   [score]  of_epm   16008 inbred 21 both 10-12wks N=10
    Wahlsten2 behavior observation (none) wildness rating, mean during rotarod   [score]  rrod   16009 inbred 21 both 10-12wks N=8
    Wahlsten2 behavior observation (none) wildness rating, mean during water escape   [score]  wmaze   16010 inbred 21 both 10-12wks N=9
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