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Project data set: Wahlsten1   (2003)

Project Survey of motor activity, behavior, and forebrain morphometry in 21 inbred strains of mice across two laboratories

Study design: baseline survey; 1 cohort.
21 strains tested     female male     Test age: 9, 12 wks

Investigators Wahlsten D, Crabbe JC   [Details, papers]

Protocol View phenotyping protocol and methods

Wahlsten1
measurements



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behavior — anxiety         elevated plus maze  
Wahlsten1
time spent in two closed arms   [s]
21 strains   age 9wks
  Inbred
Wahlsten1
number fecal boli, 5 min trial   [n]
21 strains   age 9wks
  Inbred
Wahlsten1
percent time spent in open arms vs closed   [%]
21 strains   age 9wks
  Inbred
 
behavior — anxiety         open field test  
Wahlsten1
percent of 5 min spent within 10 cm of wall   [%]
21 strains   age 9wks
  Inbred
Wahlsten1
number of fecal boli, within 5 min trial   [n]
21 strains   age 9wks
  Inbred
 
behavior — exploratory         elevated plus maze  
Wahlsten1
average distance traveled in 1 min   [cm]
21 strains   age 9wks
  Inbred
Wahlsten1
time spent in zones  
      • center hub   • two open arms 
21 strains   age 9wks
  Inbred
 
behavior — exploratory         open field test  
Wahlsten1
average distance traveled in 1 min   [cm]
21 strains   age 9wks
  Inbred
 
behavior — locomotor activity         elevated plus maze  
Wahlsten1
distance traveled [cm]  
      during minute: • 1  • 2  • 3  • 4  • 5    • time comparison  
21 strains   age 9wks
  Inbred
Wahlsten1
movement  
      • % time moving   • speed when moving 
21 strains   age 9wks
  Inbred
 
behavior — locomotor activity         open field test  
Wahlsten1
distance traveled [cm]  
      during minute: • 1  • 2  • 3  • 4  • 5    • time comparison  
21 strains   age 9wks
  Inbred
Wahlsten1
average speed over 5 min trial   [cm/sec]
21 strains   age 9wks
  Inbred
 
brain — morphology — size         histopathology  
Wahlsten1
corpus callosum  
      • length at mid-sagittal plane   • cross-sectional area at midplane   • index 
21 strains   age 12wks
  Inbred
Wahlsten1
hippocampus  
      • length at mid-sagittal plane   • cross-sectional area at midplane   • index 
21 strains   age 12wks
  Inbred
Wahlsten1
anterior commissure  
      • length at mid-sagittal plane   • cross-sectional area at midplane   • index 
21 strains   age 12wks
  Inbred
 
brain — morphology — weight         scales  
Wahlsten1
brain weight (after fixation and trimming)  
      • weight   • as percent of body weight 
21 strains   age 12wks
  Inbred


local experiment parameter  
Wahlsten1
body weight, end of testing   [g]
21 strains   age 12wks
  Inbred
Wahlsten1
tissue quality; 0=no faults, 1=one or more faults   [score]
21 strains   age 12wks
  Inbred



Number of mice tested per strain, for each measurement

  
Changelog There have been no updates or corrections to the data set since MPD release in Jul 2003  
Reference
Wahlsten D, Bachmanov A, Finn DA, Crabbe JC. Stability of inbred mouse strain differences in behavior and brain size between laboratories and across decades. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16364-9. Epub 2006 Oct 19.     PubMed 17053075     MGI


Wahlsten D, Metten P, Crabbe JC. Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T/+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum. Brain Res. 2003 May 2;971(1):47-54.     PubMed 12691836     MGI

Related papers
Mice
Strain and animal info
Note
This study was conducted on the same set of mice rated for wildness and ease of handling (Wahlsten2).

Wahlsten1 data were measured at two different laboratories. The data were pooled to produce the above MPD measurements. More on comparability of results from the two laboratories.

Note
Caution: Very low sample sizes (N < 3) are present. [View table]
Note
Some measurements were derived by MPD staff,
based on supplied data. [View list]
Note
Some measurements are not eligible for all-MPD pheno vs. pheno
correlations due to data characteristics or semantics [View list]

Wahlsten1
downloads


Individual animal data
Table format (.csv)
Individual animal data in table format, with one row per animal and one column per measurement.
Individual animal data
List format (.csv)
Individual animal data organized as one row per animal / measurement reading.
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
No supplemental data for this project. 

 See also the MPD download center for more general data download options.





 




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