Peters1: Hematology and clotting time survey in 43 inbred strains of mice (2001)

Peters LL, Cheever EM, Ellis HR, Magnani PA, Svenson KL, Von Smith R, Bogue MA. Large-scale, high-throughput screening for coagulation and hematologic phenotypes in mice. Physiol Genomics. 2002 Dec 3;11(3):185-93.   PubMed 12419856  


           
Notes
Animal identifiers were found to not always be consistent when comparing an ADVIA measurement vs. a BCS measurement, animal by animal.

Peters1 downloads
• Download Peters1 project data set     one row per animal, one column per trait
• Download Peters1 strain means, SD, N, etc.     one row per strain/sex/measure
Ontology terms mapped to Peters1 measures:
    MA:0000059   blood
    MP:0000217   abnormal leukocyte cell number
    MP:0000226   abnormal mean corpuscular volume
    MP:0000717   abnormal lymphocyte cell number
    MP:0001586   abnormal erythrocyte cell number
    MP:0001588   abnormal hemoglobin
    MP:0001589   abnormal mean corpuscular hemoglobin
    MP:0002586   abnormal platelet volume
    MP:0002596   abnormal hematocrit
    MP:0002602   abnormal eosinophil cell number
    MP:0005640   abnormal mean corpuscular hemoglobin concentration
    MP:0008849   abnormal hemoglobin concentration distribution width
    MP:0010066   abnormal red blood cell distribution width
    MP:0010213   abnormal circulating fibrinogen level
    MP:0011898   abnormal platelet cell number
    MP:0011913   abnormal reticulocyte cell number
    MP:0012354   abnormal prothrombin time
    MP:0012357   abnormal partial thromboplastin time
    MP:0012360   abnormal large unstained cell number
    MP:0012397   abnormal nucleated erythrocyte cell number
    MP:0012440   abnormal neutrophil cell number
    MP:0012441   abnormal monocyte cell number
    MP:0012442   abnormal basophil cell number
    VT:0000217   leukocyte quantity
    VT:0000222   neutrophil quantity
    VT:0000223   monocyte quantity
    VT:0000248   erythrocyte size trait
    VT:0000717   lymphocyte quantity
    VT:0001586   erythrocyte quantity
    VT:0001588   blood hemoglobin amount
    VT:0002447   erythrocyte morphology trait
    VT:0002551   blood coagulation trait
    VT:0002602   eosinophil quantity
    VT:0002607   basophil quantity
    VT:0003135   reticulocyte quantity
    VT:0003179   platelet quantity
    VT:0004152   blood iron amount
    VT:0010457   platelet size trait
    VT:3000003   fibrin formation trait
Participants Luanne L Peters       The Jackson Laboratory,  Bar Harbor, ME
Jane E Barker       The Jackson Laboratory,  Bar Harbor, ME
With: Svenson K, Von Smith R
ContactLuanne L Peters     Luanne.Peters@jax.org
AffiliationJAX Heart, Lung, and Blood Center (HLB)
Part of a series: • Inbred strains   (this project) Peters1
• AxB and BxA strains   see Peters2
• B6 controls sampled over time   see Peters3
AcknowledgementsFunding provided by Program for Genomic Applications (PGA) HL66611.

In fulfillment of NIH requirements that all information is made promptly and freely available to the research community, data are deposited in the MPD when complete.
Project type Phenotype strain survey data set
MPD identifiersPeters1     MPD:62
Data changelog 7 updates/corrections.       Initial release date: 06/2001.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Animals were evaluated using Advia 120 analyzer and Dade Behring BCS automated coagulation analyzer adapted for mice.

Summary of procedures that were conducted
• complete blood count Hematology.
• coagulation test Fibrinogen.
Mice: inbred w/CC7   43 strains   ♀♂   age 10wks   1 cohort