Peters1: Hematology and clotting time survey in 43 inbred strains of mice (2001)

Peters LL, Cheever EM, Ellis HR, Magnani PA, Svenson KL, Von Smith R, Bogue MA. Large-scale, high-throughput screening for coagulation and hematologic phenotypes in mice. Physiol Genomics. 2002 Dec 3;11(3):185-93.   PubMed 12419856  


         
Notes
Animal identifiers were found to not always be consistent when comparing an ADVIA measurement vs. a BCS measurement, animal by animal.

Peters1 downloads
• Download Peters1 project data set     one row per animal, one column per trait
• Download Peters1 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Luanne L Peters       The Jackson Laboratory Bar Harbor, ME
Jane E Barker       The Jackson Laboratory Bar Harbor, ME
With: Svenson K, Von Smith R
ContactLuanne L Peters     Luanne.Peters@jax.org
AffiliationJAX Heart, Lung, and Blood Center (HLB)
Part of a series: • Inbred strains   (this project) Peters1
• AxB and BxA strains   see Peters2
• B6 controls sampled over time   see Peters3
AcknowledgementsFunding provided by Program for Genomic Applications (PGA) HL66611.

In fulfillment of NIH requirements that all information is made promptly and freely available to the research community, data are deposited in the MPD when complete.
Project type Phenotype strain survey data set
MPD identifiersPeters1     MPD:62
Data changelog 7 updates/corrections.       Initial release date: 06/2001.
Formatted citation
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Animals were evaluated using Advia 120 analyzer and Dade Behring BCS automated coagulation analyzer adapted for mice.

Summary of procedures that were conducted
• complete blood count Hematology.
• coagulation test Fibrinogen.
Mice: inbred   43 strains   ♀♂   age 10wks   1 cohort

Select table page: First Prev Next Last
Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Peters1 6201 complete blood count (none) white blood cell count (WBC; per volume x 103)   [n/µL]  WBC inbred w/CC7 43 both 10wks N=12
    Peters1 6202 complete blood count (none) red blood cell count (RBC; per volume x 106)   [n/µL]  RBC inbred w/CC7 43 both 10wks N=12
    Peters1 6203 complete blood count (none) measured hemoglobin (HGB)   [g/dL]  mHGB inbred w/CC7 43 both 10wks N=12
    Peters1 6204 complete blood count (none) hematocrit (HCT)   [%]  HCT inbred w/CC7 43 both 10wks N=12
    Peters1 6205 complete blood count (none) mean RBC corpuscular volume (MCV)   [fL]  MCV inbred w/CC7 43 both 10wks N=12
    Peters1 6206 complete blood count (none) mean RBC corpuscular hemoglobin (MCH)   [pg]  MCH inbred w/CC7 43 both 10wks N=12
    Peters1 6207 complete blood count (none) mean RBC corpuscular hemoglobin concentration (MCHC)   [g/dL]  MCHC inbred w/CC7 43 both 10wks N=12
    Peters1 6208 complete blood count (none) RBC corpuscular hemoglobin concentration mean (CHCM)   [g/dL]  CHCM inbred w/CC7 43 both 10wks N=12
    Peters1 6209 complete blood count (none) RBC corpuscular distribution width (RDW)   [%]  RDW inbred w/CC7 43 both 10wks N=12
    Peters1 6210 complete blood count (none) hemoglobin concentration distribution width (HDW)   [g/dL]  HDW inbred w/CC7 43 both 10wks N=12
    Peters1 6211 complete blood count (none) neutrophil differential (percent of total WBC)   [%]  NEUT inbred w/CC7 43 both 10wks N=12
    Peters1 6212 complete blood count (none) lymphocyte differential (percent of total WBC)   [%]  LYM inbred w/CC7 43 both 10wks N=12
    Peters1 6213 complete blood count (none) monocyte differential (percent of total WBC)   [%]  MONO inbred w/CC7 43 both 10wks N=11
    Peters1 6214 complete blood count (none) eosinophil differential (percent of total WBC)   [%]  EOS inbred w/CC7 43 both 10wks N=11
    Peters1 6215 complete blood count (none) large unstained cell differential (percent of total WBC)   [%]  LUC inbred w/CC7 43 both 10wks N=12
    Peters1 6216 complete blood count (none) basophil differential (percent of total WBC)   [%]  BASO inbred w/CC7 43 both 10wks N=11
    Peters1 6217 complete blood count (none) reticulocyte differential (percent of total RBC)   [%]  Retic inbred w/CC7 43 both 10wks N=12
    Peters1 6218 complete blood count (none) calculated hemoglobin (HGB)   [g/dL]  cHGB inbred w/CC7 43 both 10wks N=12
    Peters1 6219 complete blood count (none) platelet count (PLT; units per volume x 103)   [n/µL]  PLT inbred w/CC7 43 both 10wks N=12
    Peters1 6220 complete blood count (none) mean platelet volume (MPV)   [fL]  MPV inbred w/CC7 43 both 10wks N=12
    Peters1 6225 coagulation test (none) fibrinogen   [mg/dL]  Fib inbred w/CC7 43 both 10wks N=10
    Peters1 6226 coagulation test (none) prothrombin time (PT)   [s]  PT inbred w/CC7 43 both 10wks N=11
    Peters1 6227 coagulation test (none) partial thromboplastin time (PTT)   [s]  PTT inbred w/CC7 43 both 10wks N=10
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