Jentsch1: Reversal learning in males of 51 BXD recombinant inbred strains of mice (2011)

Laughlin RE, Grant TL, Williams RW, Jentsch JD. Genetic dissection of behavioral flexibility: reversal learning in mice. Biol Psychiatry. 2011 Jun 1;69(11):1109-16. Epub 2011 Mar 9.   PubMed 21392734     FullText

Jentsch1 downloads
• Download Jentsch1 project data set     animal data, as uploaded
• Download Jentsch1 animal data matrix     with factor-related expansion applied as necessary
• Download Jentsch1 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators J D Jentsch       Binghamton University,  Binghamton, NY
Robert W Williams       University of Tennessee,  Memphis, TN
Participants Laughlin RE, Grant TL
ContactJ D Jentsch     Lab web site
Part of a series: • reversal learning, 51 BXD strains   (this project) Jentsch1
• cocaine study, 4 BXD strains   see Jentsch2
AcknowledgementsFunding provided by NIH DE019580, NS062410, NS048004, MH083270, MH083269, AA13499, AA13513, AA014425, DA021131
Project type Phenotype strain survey data set
MPD identifiersJentsch1     MPD:403
Data changelog No updates/corrections.       Initial release date: 06/2012.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Behavioral inflexibility was measured using discrimination acquisition and subsequent operant reversal learning to assess heritable deficits in the inhibitory control over behavior.

Procedures conducted:
• operant conditioning chamber  Reversal learning test. Impulsivity, acquisition, reversal, conditioning. Performance and latency.

Mice: BXD w/par   53 strains   ♂   age 17wks   1 experimental group