MPD: Phenotype measures mapped to MP:0001988, cocaine preference

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
CSNA03:449	CSNA03	operant conditioning chamber	cocaine	number of sessions to acquisition (1.0 mg/kg) (intravenous self administration), founders [n] acquisition_in 110188	inbred w/CC8	7	both	4-25wks	N=10	2018

CSNA03:450	CSNA03	operant conditioning chamber	cocaine	number of sessions to acquisition (1.0 mg/kg) (intravenous self administration), CC [n] acquisition_cc 110390	CC w/par	53	both	4-25wks	N=4	2018

CSNA03:451	CSNA03	operant conditioning chamber	cocaine	number of sessions to acquisition (1.0 mg/kg) (intravenous self administration), DO [n] acquisition_do 110261	DO population w/par	8	both	4-25wks	N=48	2018

CSNA03:452	CSNA03	operant conditioning chamber	cocaine	dose response, mean number of infusions (intravenous self administration) on last two stabilized sessions, founders [n] infusions_in 110189 mg/kg: 1.0 1.8 0.56 0.32 0.1 0.18 0.056 0.032 1.0 (2nd)	inbred w/CC8	8	both	4-25wks	N=14	2018

CSNA03:461	CSNA03	operant conditioning chamber	cocaine	dose response, mean number of infusions (intravenous self administration) on last two stabilized sessions, CC [n] infusions_cc 110391 mg/kg: 1.0 1.8 0.56 0.32 0.1 0.18 0.056 0.032 1.0 (2nd)	CC w/par	57	both	4-25wks	N=6	2018

CSNA03:470	CSNA03	operant conditioning chamber	cocaine	dose response, mean number of infusions (intravenous self administration) on last two stabilized sessions, DO [n] infusions_do 110262 mg/kg: 1.0 1.8 0.56 0.32 0.1 0.18 0.056 0.032 1.0 (2nd)	DO population w/par	9	both	4-25wks	N=73	2018

CSNA03:479	CSNA03	operant conditioning chamber	cocaine	extinction, active lever presses (intravenous self administration), founders [n] extinction_active_in 110198 session: 1 2 3 4 5 6 7 8 9	inbred w/CC8	7	both	4-25wks	N=7	2018

CSNA03:488	CSNA03	operant conditioning chamber	cocaine	extinction, active lever presses (intravenous self administration), CC [n] extinction_active_cc 110400 session: 1 2 3 4 5 6 7 8 9	CC w/par	54	both	4-25wks	N=3	2018

CSNA03:497	CSNA03	operant conditioning chamber	cocaine	extinction, active lever presses (intravenous self administration), DO [n] extinction_active_do 110271 session: 1 2 3 4 5 6 7 8 9	DO population w/par	8	both	4-25wks	N=39	2018

CSNA03:506	CSNA03	operant conditioning chamber	cocaine	extinction, inactive lever presses (intravenous self administration), founders [n] extinction_inactive_in 110207 session: 1 2 3 4 5 6 7 8 9	inbred w/CC8	7	both	4-25wks	N=7	2018

CSNA03:515	CSNA03	operant conditioning chamber	cocaine	extinction, inactive lever presses (intravenous self administration), CC [n] extinction_inactive_cc 110409 session: 1 2 3 4 5 6 7 8 9	CC w/par	54	both	4-25wks	N=3	2018

CSNA03:524	CSNA03	operant conditioning chamber	cocaine	extinction, inactive lever presses (intravenous self administration), DO [n] extinction_inactive_do 110280 session: 1 2 3 4 5 6 7 8 9	DO population w/par	8	both	4-25wks	N=39	2018

CSNA03:533	CSNA03	operant conditioning chamber	cocaine	reinstatement, active lever presses (intravenous self administration), founders [n] reinstatement_active_in 110216 session: 1 2	inbred w/CC8	7	both	4-25wks	N=7	2018

CSNA03:535	CSNA03	operant conditioning chamber	cocaine	reinstatement, active lever presses (intravenous self administration), CC [n] reinstatement_active_cc 110418 session: 1 2	CC w/par	54	both	4-25wks	N=3	2018

CSNA03:537	CSNA03	operant conditioning chamber	cocaine	reinstatement, active lever presses (intravenous self administration), DO [n] reinstatement_active_do 110289 session: 1 2 3	DO population w/par	8	both	4-25wks	N=42	2018

CSNA03:540	CSNA03	operant conditioning chamber	cocaine	reinstatement, inactive lever presses (intravenous self administration), founders [n] reinstatement_inactive_in 110218 session: 1 2	inbred w/CC8	7	both	4-25wks	N=7	2018

CSNA03:542	CSNA03	operant conditioning chamber	cocaine	reinstatement, inactive lever presses (intravenous self administration), CC [n] reinstatement_inactive_cc 110420 session: 1 2	CC w/par	54	both	4-25wks	N=3	2018

CSNA03:544	CSNA03	operant conditioning chamber	cocaine	reinstatement, inactive lever presses (intravenous self administration), DO [n] reinstatement_inactive_do 110292 session: 1 2 3	DO population w/par	8	both	4-25wks	N=42	2018

CSNA03:547	CSNA03	operant conditioning chamber	cocaine	reinstatement, number of infusions (intravenous self administration), founders [n] reinstatement_inf_in 110220 session: 1 2	inbred w/CC8	7	both	4-25wks	N=7	2018

CSNA03:549	CSNA03	operant conditioning chamber	cocaine	reinstatement, number of infusions (intravenous self administration), CC [n] reinstatement_inf_cc 110422 session: 1 2	CC w/par	54	both	4-25wks	N=3	2018

CSNA03:551	CSNA03	operant conditioning chamber	cocaine	reinstatement, number of infusions (intravenous self administration), DO [n] reinstatement_inf_do 110295 session: 1 2 3	DO population w/par	8	both	4-25wks	N=42	2018

Dickson2:31	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, mean number of infusions (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_infusions_mean 54831	DO population		both	12-16wks	N=35	2015

Dickson2:32	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, mean number of responses on the active lever (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_active_mean 54832	DO population		both	12-16wks	N=35	2015

Dickson2:33	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, mean number of responses on the inactive lever (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_inactive_mean 54833	DO population		both	12-16wks	N=35	2015

Dickson2:41	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, breakpoint for infusions (progressive ratio (PR) schedule), one 6h test [n] PR_infusions_breakpoint 54841	DO population		both	12-16wks	N=31	2015

Dickson2:42	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, number of presses on the active lever (progressive ratio (PR) schedule), one 6h test [n] PR_active 54842	DO population		both	12-16wks	N=31	2015

Dickson2:43	Dickson2	operant conditioning chamber	cocaine	intravenous self-administration, number of presses on the inactive lever (progressive ratio (PR) schedule), one 6h test [n] PR_inactive 54843	DO population		both	12-16wks	N=31	2015

Jentsch2:1	Jentsch2	operant conditioning chamber	cocaine	number of sessions (days) required to reach criteria for self-administration (FR1 reinforcement schedule) [d] acquisition_FR1 49701	BXD	4	both	8-17wks	N=8	2013

Jentsch2:2	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 1 - self administration: number of infusions earned [n] infusions_FR1 49702 day 1 day 3 day 5 last day	BXD	4	both	8-17wks	N=8	2013

Jentsch2:6	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 1 - discrimination index between active and inactive levers [%] discrimination_FR1 49706 day 1 day 3 day 5 last day	BXD	4	both	8-17wks	N=7	2013

Jentsch2:10	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 1 - time-out: number of responses [n] timeout_FR1 49710 day 1 day 3 day 5 last day	BXD	4	both	8-17wks	N=7	2013

Jentsch2:14	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 2 - self administration: number of infusions earned [n] infusions_FR2 49714 day 1 day 2 day 4	BXD	4	both	8-17wks	N=6	2013

Jentsch2:17	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 2 - discrimination index between active and inactive levers [%] discrimination_FR2 49717 day 1 day 2 day 4	BXD	4	both	8-17wks	N=6	2013

Jentsch2:20	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 2 - time-out: number of responses [n] timeout_FR2 49720 day 1 day 2 day 4	BXD	4	both	8-17wks	N=6	2013

Jentsch2:23	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 5 - self administration: number of infusions earned [n] infusions_FR5 49723 day 1 day 3 day 5	BXD	4	both	8-17wks	N=6	2013

Jentsch2:26	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 5 - discrimination index between active and inactive levers [%] discrimination_FR5 49726 day 1 day 3 day 5	BXD	4	both	8-17wks	N=6	2013

Jentsch2:29	Jentsch2	operant conditioning chamber	cocaine	Fixed ratio 5 - time-out: number of responses [n] timeout_FR5 49729 day 1 day 3 day 5	BXD	4	both	8-17wks	N=6	2013

CSNA03

operant conditioning chamber

cocaine

number of sessions to acquisition (1.0 mg/kg) (intravenous self administration), founders [n] acquisition_in 110188

inbred w/CC8

7

both

4-25wks

N=10

2018

CSNA03

operant conditioning chamber

cocaine

number of sessions to acquisition (1.0 mg/kg) (intravenous self administration), CC [n] acquisition_cc 110390

CC w/par

53

both

4-25wks

N=4

2018

CSNA03

operant conditioning chamber

cocaine

number of sessions to acquisition (1.0 mg/kg) (intravenous self administration), DO [n] acquisition_do 110261

DO population w/par

8

both

4-25wks

N=48

2018

CSNA03

operant conditioning chamber

cocaine

dose response, mean number of infusions (intravenous self administration) on last two stabilized sessions, founders [n] infusions_in 110189 mg/kg: 1.0 1.8 0.56 0.32 0.1 0.18 0.056 0.032 1.0 (2nd)

inbred w/CC8

8

both

4-25wks

N=14

2018

CSNA03

operant conditioning chamber

cocaine

dose response, mean number of infusions (intravenous self administration) on last two stabilized sessions, CC [n] infusions_cc 110391 mg/kg: 1.0 1.8 0.56 0.32 0.1 0.18 0.056 0.032 1.0 (2nd)

CC w/par

57

both

4-25wks

N=6

2018

CSNA03

operant conditioning chamber

cocaine

dose response, mean number of infusions (intravenous self administration) on last two stabilized sessions, DO [n] infusions_do 110262 mg/kg: 1.0 1.8 0.56 0.32 0.1 0.18 0.056 0.032 1.0 (2nd)

DO population w/par

9

both

4-25wks

N=73

2018

CSNA03

operant conditioning chamber

cocaine

extinction, active lever presses (intravenous self administration), founders [n] extinction_active_in 110198 session: 1 2 3 4 5 6 7 8 9

inbred w/CC8

7

both

4-25wks

N=7

2018

CSNA03

operant conditioning chamber

cocaine

extinction, active lever presses (intravenous self administration), CC [n] extinction_active_cc 110400 session: 1 2 3 4 5 6 7 8 9

CC w/par

54

both

4-25wks

N=3

2018

CSNA03

operant conditioning chamber

cocaine

extinction, active lever presses (intravenous self administration), DO [n] extinction_active_do 110271 session: 1 2 3 4 5 6 7 8 9

DO population w/par

8

both

4-25wks

N=39

2018

CSNA03

operant conditioning chamber

cocaine

extinction, inactive lever presses (intravenous self administration), founders [n] extinction_inactive_in 110207 session: 1 2 3 4 5 6 7 8 9

inbred w/CC8

7

both

4-25wks

N=7

2018

CSNA03

operant conditioning chamber

cocaine

extinction, inactive lever presses (intravenous self administration), CC [n] extinction_inactive_cc 110409 session: 1 2 3 4 5 6 7 8 9

CC w/par

54

both

4-25wks

N=3

2018

CSNA03

operant conditioning chamber

cocaine

extinction, inactive lever presses (intravenous self administration), DO [n] extinction_inactive_do 110280 session: 1 2 3 4 5 6 7 8 9

DO population w/par

8

both

4-25wks

N=39

2018

CSNA03

operant conditioning chamber

cocaine

reinstatement, active lever presses (intravenous self administration), founders [n] reinstatement_active_in 110216 session: 1 2

inbred w/CC8

7

both

4-25wks

N=7

2018

CSNA03

operant conditioning chamber

cocaine

reinstatement, active lever presses (intravenous self administration), CC [n] reinstatement_active_cc 110418 session: 1 2

CC w/par

54

both

4-25wks

N=3

2018

CSNA03

operant conditioning chamber

cocaine

reinstatement, active lever presses (intravenous self administration), DO [n] reinstatement_active_do 110289 session: 1 2 3

DO population w/par

8

both

4-25wks

N=42

2018

CSNA03

operant conditioning chamber

cocaine

reinstatement, inactive lever presses (intravenous self administration), founders [n] reinstatement_inactive_in 110218 session: 1 2

inbred w/CC8

7

both

4-25wks

N=7

2018

CSNA03

operant conditioning chamber

cocaine

reinstatement, inactive lever presses (intravenous self administration), CC [n] reinstatement_inactive_cc 110420 session: 1 2

CC w/par

54

both

4-25wks

N=3

2018

CSNA03

operant conditioning chamber

cocaine

reinstatement, inactive lever presses (intravenous self administration), DO [n] reinstatement_inactive_do 110292 session: 1 2 3

DO population w/par

8

both

4-25wks

N=42

2018

CSNA03

operant conditioning chamber

cocaine

reinstatement, number of infusions (intravenous self administration), founders [n] reinstatement_inf_in 110220 session: 1 2

inbred w/CC8

7

both

4-25wks

N=7

2018

CSNA03

operant conditioning chamber

cocaine

reinstatement, number of infusions (intravenous self administration), CC [n] reinstatement_inf_cc 110422 session: 1 2

CC w/par

54

both

4-25wks

N=3

2018

CSNA03

operant conditioning chamber

cocaine

reinstatement, number of infusions (intravenous self administration), DO [n] reinstatement_inf_do 110295 session: 1 2 3

DO population w/par

8

both

4-25wks

N=42

2018

Dickson2

operant conditioning chamber

cocaine

intravenous self-administration, mean number of infusions (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_infusions_mean 54831

DO population

both

12-16wks

N=35

2015

Dickson2

operant conditioning chamber

cocaine

intravenous self-administration, mean number of responses on the active lever (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_active_mean 54832

DO population

both

12-16wks

N=35

2015

Dickson2

operant conditioning chamber

cocaine

intravenous self-administration, mean number of responses on the inactive lever (fixed ratio 1 (FR1) schedule), over ten 120 min sessions [n] FR1_inactive_mean 54833

DO population

both

12-16wks

N=35

2015

Dickson2

operant conditioning chamber

cocaine

intravenous self-administration, breakpoint for infusions (progressive ratio (PR) schedule), one 6h test [n] PR_infusions_breakpoint 54841

DO population

both

12-16wks

N=31

2015

Dickson2

operant conditioning chamber

cocaine

intravenous self-administration, number of presses on the active lever (progressive ratio (PR) schedule), one 6h test [n] PR_active 54842

DO population

both

12-16wks

N=31

2015

Dickson2

operant conditioning chamber

cocaine

intravenous self-administration, number of presses on the inactive lever (progressive ratio (PR) schedule), one 6h test [n] PR_inactive 54843

DO population

both

12-16wks

N=31

2015

Jentsch2

operant conditioning chamber

cocaine

number of sessions (days) required to reach criteria for self-administration (FR1 reinforcement schedule) [d] acquisition_FR1 49701

BXD

4

both

8-17wks

N=8

2013

Jentsch2

operant conditioning chamber

cocaine

Fixed ratio 1 - self administration: number of infusions earned [n] infusions_FR1 49702 day 1 day 3 day 5 last day

BXD

4

both

8-17wks

N=8

2013

Jentsch2

operant conditioning chamber

cocaine

Fixed ratio 1 - discrimination index between active and inactive levers [%] discrimination_FR1 49706 day 1 day 3 day 5 last day

BXD

4

both

8-17wks

N=7

2013

Jentsch2

operant conditioning chamber

cocaine

Fixed ratio 1 - time-out: number of responses [n] timeout_FR1 49710 day 1 day 3 day 5 last day

BXD

4

both

8-17wks

N=7

2013

Jentsch2

operant conditioning chamber

cocaine

Fixed ratio 2 - self administration: number of infusions earned [n] infusions_FR2 49714 day 1 day 2 day 4

BXD

4

both

8-17wks

N=6

2013

Jentsch2

operant conditioning chamber

cocaine

Fixed ratio 2 - discrimination index between active and inactive levers [%] discrimination_FR2 49717 day 1 day 2 day 4

BXD

4

both

8-17wks

N=6

2013

Jentsch2

operant conditioning chamber

cocaine

Fixed ratio 2 - time-out: number of responses [n] timeout_FR2 49720 day 1 day 2 day 4

BXD

4

both

8-17wks

N=6

2013

Jentsch2

operant conditioning chamber

cocaine

Fixed ratio 5 - self administration: number of infusions earned [n] infusions_FR5 49723 day 1 day 3 day 5

BXD

4

both

8-17wks

N=6

2013

Jentsch2

operant conditioning chamber

cocaine

Fixed ratio 5 - discrimination index between active and inactive levers [%] discrimination_FR5 49726 day 1 day 3 day 5

BXD

4

both

8-17wks

N=6

2013

Jentsch2

operant conditioning chamber

cocaine

Fixed ratio 5 - time-out: number of responses [n] timeout_FR5 49729 day 1 day 3 day 5

BXD

4

both

8-17wks

N=6

2013

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