Project measure / variable:   Threadgill2   APAP300_3

ID, description, units MPD:39636   APAP300_3   serum acetaminophen (APAP), 300 mg/mL dose acetaminophen   [µg/mL]  3h  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen (APAP), 300 mg/mL dose acetaminophen 3h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means12.9   µg/mL
Median of the strain means10.8   µg/mL
SD of the strain means± 9.44
Coefficient of variation (CV)0.732
Min–max range of strain means5.76   –   28.8   µg/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 1474.5859 368.6465 6.447 0.0021
Residuals 18 1029.2583 57.181


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 5.76 2.39   5 1.07 0.415 1.92, 7.72 -0.76
C57BL/6J m 10.8 8.22   5 3.68 0.764 0.98, 21.8 -0.22
DBA/2J m 13.2 2.8   5 1.25 0.213 10.2, 16.7 0.03
LP/J m 28.8 14.8   4 7.39 0.514 7.66, 42.2 1.68
NZW/LacJ m 5.94 4.05   4 2.02 0.681 1.64, 11.4 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 5.76 3.3817 12.8648 0.0
C57BL/6J m 10.764 3.3817 17.8688 3.6592
DBA/2J m 13.16 3.3817 20.2648 6.0552
LP/J m 28.765 3.7809 36.7084 20.8216
NZW/LacJ m 5.9425 3.7809 13.8859 0.0




  GWAS USING LINEAR MIXED MODELS