Project measure / variable:   Threadgill2   APAP300_0

ID, description, units MPD:39632   APAP300_0   serum acetaminophen (APAP), 300 mg/mL dose acetaminophen   [µg/mL]  baseline  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen (APAP), 300 mg/mL dose acetaminophen baseline



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means28.1   µg/mL
Median of the strain means21.0   µg/mL
SD of the strain means± 13.5
Coefficient of variation (CV)0.483
Min–max range of strain means16.9   –   46.8   µg/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 3553.5508 888.3877 2.5306 0.0744
Residuals 19 6670.1275 351.0593


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 17.6 9.23   5 4.13 0.524 2.81, 25.4 -0.77
C57BL/6J m 21.0 12.4   5 5.56 0.592 7.63, 34.8 -0.52
DBA/2J m 46.8 20.6   5 9.19 0.44 15.2, 68.9 1.38
LP/J m 38.0 35.2   4 17.6 0.926 11.8, 86.5 0.73
NZW/LacJ m 16.9 8.8   5 3.94 0.52 5.63, 25.7 -0.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 17.622 8.3793 35.16 0.084
C57BL/6J m 21.004 8.3793 38.542 3.466
DBA/2J m 46.76 8.3793 64.298 29.222
LP/J m 38.0 9.3683 57.6081 18.3919
NZW/LacJ m 16.922 8.3793 34.46 0.0




  GWAS USING LINEAR MIXED MODELS