Project measure / variable:   Threadgill2   APAP50_6

ID, description, units MPD:39615   APAP50_6   serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]  6h  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen (APAP), 50 mg/mL dose acetaminophen 6h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means0.242   µg/mL
Median of the strain means0.228   µg/mL
SD of the strain means± 0.0866
Coefficient of variation (CV)0.358
Min–max range of strain means0.152   –   0.366   µg/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 0.1451 0.0363 0.6547 0.6312
Residuals 18 0.9976 0.0554


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 0.152 0.231   5 0.103 1.52 -1.04
C57BL/6J m 0.228 0.172   4 0.0859 0.755 -0.16
DBA/2J m 0.288 0.292   5 0.131 1.01 0.53
LP/J m 0.366 0.254   5 0.114 0.695 1.43
NZW/LacJ m 0.177 0.178   4 0.089 1.0 -0.75


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 0.152 0.1053 0.3732 0.0
C57BL/6J m 0.2275 0.1177 0.4748 0.0
DBA/2J m 0.288 0.1053 0.5092 0.0668
LP/J m 0.366 0.1053 0.5872 0.1448
NZW/LacJ m 0.1775 0.1177 0.4248 0.0




GWAS analysis not available: At least 12 strains are required