Project measure / variable:   Threadgill2   APAP50_2

ID, description, units MPD:39613   APAP50_2   serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]  2h  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen (APAP), 50 mg/mL dose acetaminophen 2h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means1.27   µg/mL
Median of the strain means0.715   µg/mL
SD of the strain means± 1.15
Coefficient of variation (CV)0.909
Min–max range of strain means0.482   –   3.24   µg/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 26.2617 6.5654 3.4356 0.0283
Residuals 19 36.3089 1.911


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 3.24 2.4   5 1.07 0.741 0.3, 6.31 1.71
C57BL/6J m 0.715 0.392   4 0.196 0.549 0.37, 1.13 -0.48
DBA/2J m 1.34 1.76   5 0.786 1.31 0.39, 4.47 0.06
LP/J m 0.562 0.3   5 0.134 0.534 0.18, 0.97 -0.61
NZW/LacJ m 0.482 0.111   5 0.0496 0.23 0.38, 0.66 -0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 3.24 0.6182 4.534 1.946
C57BL/6J m 0.715 0.6912 2.1617 0.0
DBA/2J m 1.34 0.6182 2.634 0.046
LP/J m 0.562 0.6182 1.856 0.0
NZW/LacJ m 0.482 0.6182 1.776 0.0




  GWAS USING LINEAR MIXED MODELS