Project measure / variable:   Threadgill2   APAP50_0

ID, description, units MPD:39609   APAP50_0   serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]  baseline  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen (APAP), 50 mg/mL dose acetaminophen baseline



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means2.67   µg/mL
Median of the strain means2.37   µg/mL
SD of the strain means± 1.15
Coefficient of variation (CV)0.429
Min–max range of strain means1.76   –   4.62   µg/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 22.3323 5.5831 0.6662 0.6232
Residuals 19 159.226 8.3803


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 1.94 3.64   5 1.63 1.88 -0.64
C57BL/6J m 4.62 3.15   4 1.57 0.681 1.05, 8.41 1.7
DBA/2J m 1.76 1.5   5 0.67 0.853 0.78, 4.41 -0.79
LP/J m 2.66 3.47   5 1.55 1.3 0.96, 8.86 -0.01
NZW/LacJ m 2.37 2.2   5 0.984 0.928 0.57, 5.28 -0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 1.938 1.2946 4.6477 0.0
C57BL/6J m 4.62 1.4474 7.6495 1.5905
DBA/2J m 1.758 1.2946 4.4677 0.0
LP/J m 2.66 1.2946 5.3697 0.0
NZW/LacJ m 2.372 1.2946 5.0817 0.0




GWAS analysis not available: At least 12 strains are required