Project measure / variable:   Threadgill2   APAP50_1

ID, description, units MPD:39612   APAP50_1   serum acetaminophen (APAP), 50 mg/mL dose acetaminophen   [µg/mL]  1h  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen (APAP), 50 mg/mL dose acetaminophen 1h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means2.21   µg/mL
Median of the strain means1.96   µg/mL
SD of the strain means± 0.958
Coefficient of variation (CV)0.434
Min–max range of strain means1.40   –   3.83   µg/mL
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 17.9037 4.4759 1.5121 0.2385
Residuals 19 56.2419 2.9601


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 3.83 2.86   5 1.28 0.749 2.2, 8.93 1.7
C57BL/6J m 1.64 0.917   4 0.458 0.558 1.05, 3.01 -0.59
DBA/2J m 2.2 1.93   5 0.861 0.877 0.85, 5.57 -0.01
LP/J m 1.96 1.09   5 0.489 0.558 1.17, 3.87 -0.26
NZW/LacJ m 1.4 0.57   5 0.255 0.406 0.82, 2.12 -0.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 3.826 0.7694 5.4364 2.2156
C57BL/6J m 1.6425 0.8602 3.443 0.0
DBA/2J m 2.196 0.7694 3.8064 0.5856
LP/J m 1.958 0.7694 3.5684 0.3476
NZW/LacJ m 1.404 0.7694 3.0144 0.0




GWAS analysis not available: At least 12 strains are required