Project measure / variable:   Berndt2   airway_elas_mch1

ID, description, units MPD:35192   airway_elas_mch1   lung tissue dynamic elastance (H20 pressure)   [cm/mL]  1 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Berndt2 - lung tissue dynamic elastance (H20 pressure) 1 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means53.6   cm/mL 47.9   cm/mL
Median of the strain means52.8   cm/mL 46.7   cm/mL
SD of the strain means± 8.93 ± 9.95
Coefficient of variation (CV)0.167 0.208
Min–max range of strain means38.3   –   71.8   cm/mL 33.0   –   76.3   cm/mL
Mean sample size per strain8.7   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4498.2858 4498.2858 59.5924 < 0.0001
strain 28 38458.0961 1373.5034 18.1959 < 0.0001
sex:strain 28 7421.4286 265.051 3.5113 < 0.0001
Residuals 478 36081.4316 75.4842


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 44.3 5.22   9 1.74 0.118 36.6, 53.4 -1.04
129S1/SvImJ m 48.5 8.12   8 2.87 0.168 40.4, 65.0 0.06
A/J f 52.8 10.3   10 3.25 0.195 42.2, 68.8 -0.08
A/J m 44.8 5.85   9 1.95 0.131 39.0, 56.6 -0.31
AKR/J f 51.7 8.29   9 2.76 0.16 40.5, 68.6 -0.21
AKR/J m 62.6 13.5   10 4.28 0.216 49.0, 82.8 1.48
BALB/cByJ f 44.2 8.33   8 2.95 0.188 33.3, 61.2 -1.05
BALB/cByJ m 46.6 24.7   10 7.8 0.529 28.7, 114.0 -0.13
BALB/cJ f 57.2 14.0   8 4.93 0.244 39.4, 83.9 0.41
BALB/cJ m 33.6 5.53   12 1.6 0.165 22.9, 42.4 -1.44
BTBR T+ Itpr3tf/J f 41.4 6.34   10 2.01 0.153 31.9, 52.5 -1.36
BTBR T+ Itpr3tf/J m 33.8 4.74   10 1.5 0.14 24.1, 40.6 -1.42
BUB/BnJ f 48.3 8.83   9 2.94 0.183 39.6, 67.7 -0.59
BUB/BnJ m 42.3 3.97   10 1.26 0.0939 34.8, 47.4 -0.56
C3H/HeJ f 39.5 3.1   10 0.981 0.0786 34.6, 44.5 -1.57
C3H/HeJ m 34.1 4.43   9 1.48 0.13 28.0, 40.6 -1.39
C57BL/10J f 60.5 6.77   9 2.26 0.112 49.5, 73.8 0.78
C57BL/10J m 46.7 7.81   10 2.47 0.167 37.1, 63.7 -0.12
C57BL/6J f 52.1 4.22   7 1.59 0.0809 47.3, 59.2 -0.16
C57BL/6J m 50.1 6.14   8 2.17 0.123 40.3, 59.6 0.22
C57BLKS/J f 56.0 6.4   9 2.13 0.114 48.4, 65.8 0.27
C57BLKS/J m 51.9 8.3   12 2.4 0.16 36.8, 62.1 0.4
C57BR/cdJ f 63.4 17.4   7 6.59 0.275 49.1, 97.3 1.1
C57BR/cdJ m 45.6 7.12   12 2.06 0.156 33.6, 56.5 -0.23
C57L/J f 48.1 9.39   6 3.83 0.195 40.7, 65.2 -0.61
C57L/J m 45.0 11.9   10 3.76 0.265 35.7, 73.2 -0.29
CBA/J f 56.8 4.48   8 1.58 0.0788 50.9, 62.6 0.36
CBA/J m 50.7 5.35   11 1.61 0.105 43.4, 61.4 0.28
CE/J f 47.6 3.93   9 1.31 0.0827 43.0, 53.4 -0.67
CE/J m 35.2 4.3   9 1.43 0.122 28.9, 41.5 -1.27
DBA/1J f 66.0 9.91   9 3.3 0.15 51.9, 82.7 1.39
DBA/1J m 65.8 8.98   11 2.71 0.136 53.6, 77.9 1.8
DBA/2J f 58.5 8.07   10 2.55 0.138 47.4, 70.6 0.55
DBA/2J m 47.7 8.03   10 2.54 0.169 36.8, 64.6 -0.02
FVB/NJ f 52.8 9.84   10 3.11 0.187 42.4, 69.5 -0.08
FVB/NJ m 51.5 8.95   10 2.83 0.174 39.4, 69.0 0.36
I/LnJ f 51.6 7.68   9 2.56 0.149 43.6, 65.8 -0.22
I/LnJ m 48.9 9.14   8 3.23 0.187 39.1, 68.0 0.1
KK/HlJ f 44.0 6.13   9 2.04 0.139 37.9, 53.8 -1.07
KK/HlJ m 45.0 3.49   10 1.1 0.0777 40.0, 52.0 -0.29
LP/J f 54.2 8.92   9 2.97 0.165 46.9, 74.8 0.07
LP/J m 44.5 2.85   12 0.823 0.064 39.8, 49.2 -0.34
NOD/ShiLtJ f 59.9 7.38   9 2.46 0.123 49.7, 72.1 0.71
NOD/ShiLtJ m 44.3 4.61   11 1.39 0.104 39.3, 52.9 -0.36
NON/ShiLtJ f 43.1 4.73   7 1.79 0.11 36.5, 48.8 -1.17
NON/ShiLtJ m 39.8 4.89   7 1.85 0.123 32.4, 46.2 -0.81
NZW/LacJ f 38.3 2.55   8 0.9 0.0665 33.8, 41.3 -1.71
NZW/LacJ m 33.0 4.22   10 1.34 0.128 28.3, 40.9 -1.5
PL/J f 71.8 10.6   9 3.55 0.148 52.5, 85.8 2.04
PL/J m 56.2 7.11   8 2.51 0.126 50.3, 72.9 0.84
RIIIS/J f 55.9 2.68   4 1.34 0.048 51.9, 57.3 0.26
RIIIS/J m 58.1 12.0   9 4.0 0.206 49.1, 89.1 1.03
SJL/J f 66.9 10.7   8 3.77 0.159 54.5, 82.4 1.49
SJL/J m 56.7 7.99   12 2.31 0.141 47.5, 72.0 0.89
SM/J f 69.5 9.95   10 3.15 0.143 52.6, 87.7 1.79
SM/J m 76.3 14.9   8 5.25 0.195 61.7, 99.9 2.86
SWR/J f 56.8 9.8   9 3.27 0.172 44.2, 74.3 0.36
SWR/J m 49.4 8.38   12 2.42 0.17 38.2, 65.6 0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 44.3333 2.8961 50.0239 38.6428
129S1/SvImJ m 48.4625 3.0717 54.4983 42.4267
A/J f 52.77 2.7474 58.1685 47.3715
A/J m 44.7667 2.8961 50.4572 39.0761
AKR/J f 51.7222 2.8961 57.4128 46.0317
AKR/J m 62.6 2.7474 67.9985 57.2015
BALB/cByJ f 44.2375 3.0717 50.2733 38.2017
BALB/cByJ m 46.57 2.7474 51.9685 41.1715
BALB/cJ f 57.2 3.0717 63.2358 51.1642
BALB/cJ m 33.5583 2.5081 38.4865 28.6302
BTBR T+ Itpr3tf/J f 41.4 2.7474 46.7985 36.0015
BTBR T+ Itpr3tf/J m 33.81 2.7474 39.2085 28.4115
BUB/BnJ f 48.3333 2.8961 54.0239 42.6428
BUB/BnJ m 42.33 2.7474 47.7285 36.9315
C3H/HeJ f 39.49 2.7474 44.8885 34.0915
C3H/HeJ m 34.0556 2.8961 39.7461 28.365
C57BL/10J f 60.4667 2.8961 66.1572 54.7761
C57BL/10J m 46.7 2.7474 52.0985 41.3015
C57BL/6J f 52.1429 3.2838 58.5954 45.6904
C57BL/6J m 50.0875 3.0717 56.1233 44.0517
C57BLKS/J f 56.0444 2.8961 61.735 50.3539
C57BLKS/J m 51.925 2.5081 56.8532 46.9968
C57BR/cdJ f 63.3857 3.2838 69.8382 56.9332
C57BR/cdJ m 45.5583 2.5081 50.4865 40.6302
C57L/J f 48.0667 3.5469 55.0362 41.0972
C57L/J m 44.99 2.7474 50.3885 39.5915
CBA/J f 56.775 3.0717 62.8108 50.7392
CBA/J m 50.7364 2.6196 55.8837 45.589
CE/J f 47.5778 2.8961 53.2683 41.8872
CE/J m 35.2444 2.8961 40.935 29.5539
DBA/1J f 65.9889 2.8961 71.6795 60.2983
DBA/1J m 65.8091 2.6196 70.9564 60.6618
DBA/2J f 58.47 2.7474 63.8685 53.0715
DBA/2J m 47.65 2.7474 53.0485 42.2515
FVB/NJ f 52.75 2.7474 58.1485 47.3515
FVB/NJ m 51.48 2.7474 56.8785 46.0815
I/LnJ f 51.6 2.8961 57.2906 45.9094
I/LnJ m 48.95 3.0717 54.9858 42.9142
KK/HlJ f 44.0444 2.8961 49.735 38.3539
KK/HlJ m 44.98 2.7474 50.3785 39.5815
LP/J f 54.2 2.8961 59.8906 48.5094
LP/J m 44.5167 2.5081 49.4448 39.5885
NOD/ShiLtJ f 59.8556 2.8961 65.5461 54.165
NOD/ShiLtJ m 44.3182 2.6196 49.4655 39.1709
NON/ShiLtJ f 43.1143 3.2838 49.5668 36.6618
NON/ShiLtJ m 39.7571 3.2838 46.2096 33.3046
NZW/LacJ f 38.2625 3.0717 44.2983 32.2267
NZW/LacJ m 33.02 2.7474 38.4185 27.6215
PL/J f 71.7667 2.8961 77.4572 66.0761
PL/J m 56.2375 3.0717 62.2733 50.2017
RIIIS/J f 55.925 4.3441 64.4609 47.3891
RIIIS/J m 58.0556 2.8961 63.7461 52.365
SJL/J f 66.9 3.0717 72.9358 60.8642
SJL/J m 56.7083 2.5081 61.6365 51.7802
SM/J f 69.47 2.7474 74.8685 64.0715
SM/J m 76.275 3.0717 82.3108 70.2392
SWR/J f 56.8222 2.8961 62.5128 51.1317
SWR/J m 49.3583 2.5081 54.2865 44.4302


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 46.3979 2.1108 50.5456 42.2502
A/J both 48.7683 1.996 52.6903 44.8464
AKR/J both 57.1611 1.996 61.0831 53.2392
BALB/cByJ both 45.4038 2.0606 49.4527 41.3548
BALB/cJ both 45.3792 1.9828 49.2752 41.4831
BTBR T+ Itpr3tf/J both 37.605 1.9427 41.4224 33.7876
BUB/BnJ both 45.3317 1.996 49.2536 41.4097
C3H/HeJ both 36.7728 1.996 40.6947 32.8508
C57BL/10J both 53.5833 1.996 57.5053 49.6614
C57BL/6J both 51.1152 2.2483 55.5329 46.6975
C57BLKS/J both 53.9847 1.9156 57.7487 50.2208
C57BR/cdJ both 54.472 2.066 58.5316 50.4124
C57L/J both 46.5283 2.2433 50.9362 42.1204
CBA/J both 53.7557 2.0185 57.722 49.7894
CE/J both 41.4111 2.0478 45.435 37.3873
DBA/1J both 65.899 1.9525 69.7356 62.0624
DBA/2J both 53.06 1.9427 56.8774 49.2426
FVB/NJ both 52.115 1.9427 55.9324 48.2976
I/LnJ both 50.275 2.1108 54.4227 46.1273
KK/HlJ both 44.5122 1.996 48.4342 40.5903
LP/J both 49.3583 1.9156 53.1223 45.5944
NOD/ShiLtJ both 52.0869 1.9525 55.9235 48.2503
NON/ShiLtJ both 41.4357 2.322 45.9983 36.8731
NZW/LacJ both 35.6413 2.0606 39.6902 31.5923
PL/J both 64.0021 2.1108 68.1498 59.8544
RIIIS/J both 56.9903 2.6105 62.1197 51.8609
SJL/J both 61.8042 1.9828 65.7002 57.9081
SM/J both 72.8725 2.0606 76.9214 68.8236
SWR/J both 53.0903 1.9156 56.8542 49.3263




  GWAS USING LINEAR MIXED MODELS