Project measure / variable:   Berndt2   airway_elas_mch30


  STRAIN COMPARISON PLOT
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Berndt2 - lung tissue dynamic elastance (H20 pressure) 30 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains26 strains
Mean of the strain means93.4   cm/mL 82.6   cm/mL
Median of the strain means94.5   cm/mL 80.3   cm/mL
SD of the strain means± 21.4 ± 18.0
Coefficient of variation (CV)0.229 0.218
Min–max range of strain means56.1   –   138   cm/mL 46.8   –   125   cm/mL
Mean sample size per strain6.5   mice 5.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4960.9669 4960.9669 9.5459 0.0022
strain 23 60144.4753 2614.9772 5.0317 < 0.0001
sex:strain 23 35748.003 1554.261 2.9907 < 0.0001
Residuals 251 130443.6663 519.6959


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 56.1 14.8   9 4.92 0.263 42.7, 81.9 -1.74
129S1/SvImJ m 74.4 31.7   6 12.9 0.426 44.5, 133.0 -0.45
A/J f 129.0 52.1   6 21.3 0.406 67.1, 195.0 1.67
AKR/J f 107.0 31.3   9 10.4 0.292 70.7, 174.0 0.64
BALB/cByJ f 138.0 24.0   5 10.7 0.174 102.0, 169.0 2.09
BALB/cByJ m 72.8 22.2   6 9.05 0.305 46.7, 108.0 -0.54
BALB/cJ f 104.0 30.1   5 13.5 0.29 72.0, 137.0 0.5
BALB/cJ m 73.9 31.0   9 10.3 0.419 32.6, 112.0 -0.48
BTBR T+ Itpr3tf/J f 76.2 12.6   4 6.29 0.165 63.3, 89.2 -0.8
BTBR T+ Itpr3tf/J m 65.7 17.8   5 7.97 0.271 47.4, 88.6 -0.94
BUB/BnJ f 111.0 21.3   5 9.51 0.192 86.2, 142.0 0.83
BUB/BnJ m 95.1 29.1   3 16.8 0.307 72.6, 128.0 0.7
C3H/HeJ f 74.0 13.2   7 4.97 0.178 51.8, 87.4 -0.9
C3H/HeJ m 49.2 11.1   5 4.98 0.226 35.4, 63.3 -1.85
C57BL/10J f 76.6 23.1   8 8.15 0.301 57.5, 131.0 -0.78
C57BL/10J m 80.0 16.0   6 6.52 0.2 57.5, 107.0 -0.14
C57BL/6J f 65.6 15.8   6 6.45 0.241 52.0, 95.6 -1.3
C57BL/6J m 82.9 33.9   5 15.2 0.409 51.4, 133.0 0.02
C57BLKS/J f 96.8 15.9   6 6.48 0.164 78.1, 119.0 0.16
C57BLKS/J m 87.7 26.8   5 12.0 0.306 61.7, 121.0 0.29
C57BR/cdJ f 118.0 4.51   4 2.25 0.0381 112.0, 122.0 1.15
C57BR/cdJ m 71.1 18.8   9 6.26 0.264 52.6, 106.0 -0.64
C57L/J f 71.1 20.0   4 9.98 0.281 55.7, 97.9 -1.04
C57L/J m 77.9 26.7   8 9.44 0.343 51.0, 122.0 -0.26
CBA/J f 93.0 25.8   8 9.14 0.278 66.6, 146.0 -0.02
CBA/J m 73.8 17.4   9 5.81 0.236 54.4, 110.0 -0.49
CE/J f 96.0 26.2   8 9.28 0.273 62.1, 132.0 0.12
CE/J m 69.9 15.5   9 5.15 0.221 44.1, 88.1 -0.7
DBA/1J f 108.0 24.5   2   17.3 0.228 90.3, 125.0 0.68
DBA/1J m 125.0 25.1   5 11.2 0.201 91.0, 149.0 2.36
DBA/2J f 107.0 33.3   6 13.6 0.311 60.5, 142.0 0.64
DBA/2J m 104.0 5.43   3 3.14 0.0522 99.3, 110.0 1.19
FVB/NJ f 84.8 31.6   10 10.0 0.373 52.8, 160.0 -0.4
FVB/NJ m 91.6 31.7   3 18.3 0.346 65.7, 127.0 0.5
I/LnJ m 80.7 0.0   1   0.0 0.0 80.7, 80.7 -0.1
KK/HlJ f 90.2 23.9   5 10.7 0.265 60.6, 119.0 -0.15
LP/J f 61.8 13.8   8 4.88 0.223 49.6, 90.2 -1.47
LP/J m 78.4 17.4   4 8.71 0.222 66.1, 104.0 -0.23
NOD/ShiLtJ f 96.8 14.6   7 5.52 0.151 80.0, 117.0 0.16
NOD/ShiLtJ m 96.0 26.7   5 12.0 0.278 59.7, 133.0 0.75
NON/ShiLtJ f 79.1 20.7   7 7.84 0.262 59.6, 117.0 -0.67
NON/ShiLtJ m 67.8 8.19   5 3.66 0.121 56.9, 76.3 -0.82
NZW/LacJ f 80.6 32.3   6 13.2 0.401 61.8, 146.0 -0.6
NZW/LacJ m 46.8 7.74   8 2.74 0.165 34.2, 56.4 -1.98
PL/J f 104.0 21.0   9 7.02 0.202 75.7, 134.0 0.5
PL/J m 94.6 22.0   5 9.83 0.232 58.9, 116.0 0.67
RIIIS/J f 135.0 0.0   1   0.0 0.0 135.0, 135.0 1.95
RIIIS/J m 82.5 16.3   6 6.66 0.198 64.6, 108.0 0.0
SJL/J f 83.8 12.9   8 4.56 0.154 64.1, 102.0 -0.45
SJL/J m 116.0 40.7   6 16.6 0.349 92.0, 198.0 1.86
SM/J f 97.8 21.0   10 6.64 0.215 74.8, 141.0 0.21
SM/J m 107.0 19.2   2   13.5 0.178 93.9, 121.0 1.36
SWR/J f 72.5 15.6   8 5.52 0.215 56.9, 105.0 -0.97
SWR/J m 81.5 32.4   8 11.5 0.397 54.0, 142.0 -0.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 56.1222 7.5989 71.088 41.1564
129S1/SvImJ m 74.3667 9.3068 92.696 56.0374
BALB/cByJ f 137.8 10.1951 157.8788 117.7212
BALB/cByJ m 72.75 9.3068 91.0793 54.4207
BALB/cJ f 103.74 10.1951 123.8188 83.6612
BALB/cJ m 73.9444 7.5989 88.9103 58.9786
BTBR T+ Itpr3tf/J f 76.2 11.3984 98.6487 53.7513
BTBR T+ Itpr3tf/J m 65.66 10.1951 85.7388 45.5812
BUB/BnJ f 110.72 10.1951 130.7988 90.6412
BUB/BnJ m 95.0667 13.1618 120.9882 69.1451
C3H/HeJ f 74.0429 8.6164 91.0125 57.0732
C3H/HeJ m 49.24 10.1951 69.3188 29.1612
C57BL/10J f 76.6375 8.0599 92.5112 60.7638
C57BL/10J m 79.9833 9.3068 98.3126 61.654
C57BL/6J f 65.65 9.3068 83.9793 47.3207
C57BL/6J m 82.94 10.1951 103.0188 62.8612
C57BLKS/J f 96.7667 9.3068 115.096 78.4374
C57BLKS/J m 87.68 10.1951 107.7588 67.6012
C57BR/cdJ f 118.5 11.3984 140.9487 96.0513
C57BR/cdJ m 71.0667 7.5989 86.0325 56.1008
C57L/J f 71.075 11.3984 93.5237 48.6263
C57L/J m 77.9375 8.0599 93.8112 62.0638
CBA/J f 93.0375 8.0599 108.9112 77.1638
CBA/J m 73.8 7.5989 88.7658 58.8342
CE/J f 96.0 8.0599 111.8737 80.1263
CE/J m 69.8667 7.5989 84.8325 54.9008
DBA/1J f 107.65 16.1198 139.3973 75.9027
DBA/1J m 124.6 10.1951 144.6788 104.5212
DBA/2J f 107.0833 9.3068 125.4126 88.754
DBA/2J m 104.1 13.1618 130.0216 78.1784
FVB/NJ f 84.84 7.209 99.0378 70.6422
FVB/NJ m 91.6333 13.1618 117.5549 65.7118
LP/J f 61.8125 8.0599 77.6862 45.9388
LP/J m 78.45 11.3984 100.8987 56.0013
NOD/ShiLtJ f 96.7857 8.6164 113.7554 79.8161
NOD/ShiLtJ m 96.04 10.1951 116.1188 75.9612
NON/ShiLtJ f 79.1429 8.6164 96.1125 62.1732
NON/ShiLtJ m 67.84 10.1951 87.9188 47.7612
NZW/LacJ f 80.5667 9.3068 98.896 62.2374
NZW/LacJ m 46.7875 8.0599 62.6612 30.9138
PL/J f 104.3889 7.5989 119.3547 89.4231
PL/J m 94.6 10.1951 114.6788 74.5212
SJL/J f 83.775 8.0599 99.6487 67.9013
SJL/J m 116.5 9.3068 134.8293 98.1707
SM/J f 97.77 7.209 111.9678 83.5722
SM/J m 107.45 16.1198 139.1973 75.7027
SWR/J f 72.4875 8.0599 88.3612 56.6138
SWR/J m 81.5375 8.0599 97.4112 65.6638


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 65.2444 6.0075 77.076 53.4129
BALB/cByJ both 105.275 6.9021 118.8684 91.6816
BALB/cJ both 88.8422 6.3577 101.3635 76.3209
BTBR T+ Itpr3tf/J both 70.93 7.6463 85.9891 55.8709
BUB/BnJ both 102.8933 8.3242 119.2876 86.4991
C3H/HeJ both 61.6414 6.6742 74.7861 48.4968
C57BL/10J both 78.3104 6.1559 90.4341 66.1867
C57BL/6J both 74.295 6.9021 87.8884 60.7016
C57BLKS/J both 92.2233 6.9021 105.8167 78.6299
C57BR/cdJ both 94.7833 6.8496 108.2733 81.2933
C57L/J both 74.5062 6.9801 88.2532 60.7593
CBA/J both 83.4187 5.5386 94.3269 72.5106
CE/J both 82.9333 5.5386 93.8415 72.0252
DBA/1J both 116.125 9.5366 134.907 97.343
DBA/2J both 105.5917 8.0599 121.4653 89.718
FVB/NJ both 88.2367 7.5034 103.0142 73.4591
LP/J both 70.1313 6.9801 83.8782 56.3843
NOD/ShiLtJ both 96.4129 6.6742 109.5575 83.2682
NON/ShiLtJ both 73.4914 6.6742 86.6361 60.3468
NZW/LacJ both 63.6771 6.1559 75.8008 51.5534
PL/J both 99.4944 6.3577 112.0158 86.9731
SJL/J both 100.1375 6.1559 112.2612 88.0138
SM/J both 102.61 8.8292 119.9987 85.2213
SWR/J both 77.0125 5.6992 88.2369 65.7881




  GWAS USING LINEAR MIXED MODELS