Project measure / variable:   Berndt2   tidal_vol_slope

ID, description, units MPD:35172   tidal_vol_slope   tidal volume   [mL]  response index  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - tidal volume response index



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.167   mL 0.199   mL
Median of the strain means0.182   mL 0.216   mL
SD of the strain means± 0.142 ± 0.134
Coefficient of variation (CV)0.848 0.673
Min–max range of strain means-0.113   –   0.456   mL -0.0317   –   0.388   mL
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1246 0.1246 5.8317 0.0162
strain 28 7.5703 0.2704 12.6514 < 0.0001
sex:strain 28 1.2871 0.046 2.151 0.0007
Residuals 412 8.8047 0.0214


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.41 0.152   8 0.0538 0.371 0.184, 0.592 1.71
129S1/SvImJ m 0.366 0.205   8 0.0725 0.561 0.069, 0.731 1.24
A/J f 0.129 0.11   8 0.0389 0.853 -0.004, 0.255 -0.27
A/J m 0.215 0.0772   8 0.0273 0.359 0.116, 0.34 0.12
AKR/J f 0.182 0.125   8 0.044 0.685 -0.001, 0.336 0.1
AKR/J m 0.324 0.122   8 0.043 0.375 0.11, 0.502 0.93
BALB/cByJ f 0.0617 0.0697   8 0.0247 1.13 -0.03, 0.153 -0.74
BALB/cByJ m 0.0101 0.0415   8 0.0147 4.1 -0.039, 0.062 -1.41
BALB/cJ f -0.0919 0.0851   10 0.0269 -0.926 -0.245, 0.045 -1.83
BALB/cJ m -0.0317 0.124   10 0.0392 -3.91 -0.232, 0.187 -1.72
BTBR T+ Itpr3tf/J f 0.456 0.164   8 0.058 0.36 0.212, 0.647 2.04
BTBR T+ Itpr3tf/J m 0.198 0.0974   8 0.0344 0.492 0.059, 0.359 -0.01
BUB/BnJ f 0.223 0.137   7 0.0518 0.615 -0.048, 0.372 0.39
BUB/BnJ m 0.267 0.0573   8 0.0203 0.214 0.196, 0.371 0.51
C3H/HeJ f 0.052 0.108   8 0.0382 2.08 -0.099, 0.2 -0.81
C3H/HeJ m 0.102 0.144   8 0.0509 1.42 -0.101, 0.287 -0.73
C57BL/10J f 0.242 0.112   8 0.0397 0.463 0.05, 0.371 0.53
C57BL/10J m 0.364 0.101   7 0.0381 0.277 0.221, 0.495 1.23
C57BL/6J f 0.24 0.126   7 0.0477 0.527 0.116, 0.446 0.51
C57BL/6J m 0.354 0.204   13 0.0566 0.577 -0.032, 0.631 1.15
C57BLKS/J f 0.247 0.236   11 0.0711 0.953 -0.094, 0.626 0.56
C57BLKS/J m 0.388 0.195   8 0.0691 0.504 0.156, 0.656 1.41
C57BR/cdJ f 0.263 0.289   6 0.118 1.1 -0.305, 0.462 0.68
C57BR/cdJ m 0.351 0.243   8 0.086 0.694 0.031, 0.767 1.13
C57L/J f 0.296 0.0721   8 0.0255 0.243 0.187, 0.394 0.91
C57L/J m 0.295 0.0803   8 0.0284 0.272 0.15, 0.4 0.71
CBA/J f 0.388 0.0867   8 0.0306 0.223 0.247, 0.522 1.56
CBA/J m 0.346 0.0892   8 0.0316 0.258 0.211, 0.481 1.1
CE/J f 0.087 0.158   8 0.0559 1.82 -0.17, 0.368 -0.57
CE/J m 0.0541 0.106   9 0.0354 1.96 -0.163, 0.188 -1.08
DBA/1J f 0.243 0.116   10 0.0367 0.478 0.126, 0.434 0.53
DBA/1J m 0.293 0.125   8 0.0442 0.427 0.179, 0.565 0.7
DBA/2J f 0.229 0.1   8 0.0354 0.437 0.079, 0.402 0.44
DBA/2J m 0.212 0.164   10 0.0519 0.772 -0.205, 0.328 0.1
FVB/NJ f 0.0435 0.302   8 0.107 6.94 -0.455, 0.415 -0.87
FVB/NJ m 0.216 0.264   7 0.0999 1.22 -0.118, 0.571 0.12
I/LnJ f 0.128 0.108   7 0.0408 0.841 0.03, 0.327 -0.28
I/LnJ m 0.298 0.148   5 0.0661 0.497 0.05, 0.436 0.74
KK/HlJ f 0.24 0.104   8 0.0369 0.435 0.117, 0.422 0.51
KK/HlJ m 0.238 0.0378   6 0.0154 0.159 0.194, 0.288 0.29
LP/J f -0.113 0.142   8 0.0504 -1.26 -0.355, 0.121 -1.98
LP/J m -0.0156 0.129   8 0.0456 -8.25 -0.232, 0.207 -1.6
NOD/ShiLtJ f 0.28 0.1   8 0.0354 0.357 0.115, 0.442 0.8
NOD/ShiLtJ m 0.173 0.118   8 0.0416 0.681 -0.061, 0.297 -0.2
NON/ShiLtJ f 0.0881 0.118   8 0.0417 1.34 -0.048, 0.297 -0.56
NON/ShiLtJ m 0.0163 0.0985   8 0.0348 6.06 -0.109, 0.157 -1.37
NZW/LacJ f 0.159 0.108   8 0.0382 0.68 0.007, 0.339 -0.06
NZW/LacJ m 0.0716 0.0821   8 0.029 1.15 -0.067, 0.186 -0.95
PL/J f -0.0351 0.0971   8 0.0343 -2.76 -0.147, 0.119 -1.43
PL/J m 0.00375 0.184   8 0.065 49.0 -0.188, 0.34 -1.46
RIIIS/J f 0.212 0.12   8 0.0425 0.567 -0.032, 0.365 0.32
RIIIS/J m 0.0905 0.193   8 0.0682 2.13 -0.18, 0.365 -0.81
SJL/J f -0.0143 0.163   8 0.0578 -11.5 -0.215, 0.22 -1.28
SJL/J m 0.0615 0.209   8 0.074 3.4 -0.206, 0.42 -1.03
SM/J f 0.18 0.0766   8 0.0271 0.426 0.067, 0.313 0.09
SM/J m 0.234 0.254   8 0.0897 1.08 -0.191, 0.679 0.26
SWR/J f 0.024 0.0676   8 0.0239 2.82 -0.122, 0.075 -1.01
SWR/J m 0.284 0.0784   9 0.0261 0.275 0.179, 0.425 0.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.4102 0.0517 0.5118 0.3087
129S1/SvImJ m 0.3658 0.0517 0.4673 0.2642
A/J f 0.1291 0.0517 0.2307 0.0275
A/J m 0.2151 0.0517 0.3167 0.1135
AKR/J f 0.1819 0.0517 0.2835 0.0803
AKR/J m 0.3241 0.0517 0.4257 0.2225
BALB/cByJ f 0.0617 0.0517 0.1633 -0.0398
BALB/cByJ m 0.0101 0.0517 0.1117 -0.0915
BALB/cJ f -0.0919 0.0462 -0.001 -0.1828
BALB/cJ m -0.0317 0.0462 0.0592 -0.1226
BTBR T+ Itpr3tf/J f 0.4558 0.0517 0.5573 0.3542
BTBR T+ Itpr3tf/J m 0.1981 0.0517 0.2997 0.0965
BUB/BnJ f 0.223 0.0553 0.3316 0.1144
BUB/BnJ m 0.2674 0.0517 0.369 0.1658
C3H/HeJ f 0.052 0.0517 0.1536 -0.0496
C3H/HeJ m 0.1015 0.0517 0.2031 -0.0001
C57BL/10J f 0.2425 0.0517 0.3441 0.1409
C57BL/10J m 0.3637 0.0553 0.4723 0.2551
C57BL/6J f 0.2397 0.0553 0.3483 0.1311
C57BL/6J m 0.3536 0.0405 0.4333 0.2739
C57BLKS/J f 0.2474 0.0441 0.334 0.1607
C57BLKS/J m 0.3879 0.0517 0.4895 0.2863
C57BR/cdJ f 0.2632 0.0597 0.3805 0.1459
C57BR/cdJ m 0.3507 0.0517 0.4523 0.2492
C57L/J f 0.2962 0.0517 0.3978 0.1947
C57L/J m 0.2947 0.0517 0.3963 0.1932
CBA/J f 0.3885 0.0517 0.4901 0.2869
CBA/J m 0.3461 0.0517 0.4477 0.2445
CE/J f 0.087 0.0517 0.1886 -0.0146
CE/J m 0.0541 0.0487 0.1499 -0.0417
DBA/1J f 0.2425 0.0462 0.3334 0.1516
DBA/1J m 0.2927 0.0517 0.3943 0.1912
DBA/2J f 0.2294 0.0517 0.331 0.1278
DBA/2J m 0.2124 0.0462 0.3033 0.1215
FVB/NJ f 0.0435 0.0517 0.1451 -0.0581
FVB/NJ m 0.2159 0.0553 0.3245 0.1072
I/LnJ f 0.1284 0.0553 0.237 0.0198
I/LnJ m 0.2978 0.0654 0.4263 0.1693
KK/HlJ f 0.2404 0.0517 0.342 0.1388
KK/HlJ m 0.238 0.0597 0.3553 0.1207
LP/J f -0.1135 0.0517 -0.0119 -0.2151
LP/J m -0.0156 0.0517 0.086 -0.1172
NOD/ShiLtJ f 0.2797 0.0517 0.3813 0.1782
NOD/ShiLtJ m 0.173 0.0517 0.2746 0.0714
NON/ShiLtJ f 0.0881 0.0517 0.1897 -0.0135
NON/ShiLtJ m 0.0162 0.0517 0.1178 -0.0853
NZW/LacJ f 0.159 0.0517 0.2606 0.0574
NZW/LacJ m 0.0716 0.0517 0.1732 -0.03
PL/J f -0.0351 0.0517 0.0665 -0.1367
PL/J m 0.0037 0.0517 0.1053 -0.0978
RIIIS/J f 0.2119 0.0517 0.3135 0.1103
RIIIS/J m 0.0905 0.0517 0.1921 -0.0111
SJL/J f -0.0143 0.0517 0.0873 -0.1158
SJL/J m 0.0615 0.0517 0.1631 -0.0401
SM/J f 0.1796 0.0517 0.2812 0.078
SM/J m 0.2344 0.0517 0.336 0.1328
SWR/J f 0.024 0.0517 0.1256 -0.0776
SWR/J m 0.2844 0.0487 0.3802 0.1887


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.388 0.0365 0.4598 0.3162
A/J both 0.1721 0.0365 0.244 0.1003
AKR/J both 0.253 0.0365 0.3248 0.1812
BALB/cByJ both 0.0359 0.0365 0.1078 -0.0359
BALB/cJ both -0.0618 0.0327 0.0025 -0.1261
BTBR T+ Itpr3tf/J both 0.3269 0.0365 0.3988 0.2551
BUB/BnJ both 0.2452 0.0378 0.3196 0.1708
C3H/HeJ both 0.0767 0.0365 0.1486 0.0049
C57BL/10J both 0.3031 0.0378 0.3775 0.2287
C57BL/6J both 0.2967 0.0343 0.364 0.2293
C57BLKS/J both 0.3176 0.034 0.3844 0.2509
C57BR/cdJ both 0.307 0.0395 0.3846 0.2294
C57L/J both 0.2955 0.0365 0.3673 0.2237
CBA/J both 0.3673 0.0365 0.4392 0.2955
CE/J both 0.0706 0.0355 0.1404 0.0007
DBA/1J both 0.2676 0.0347 0.3358 0.1995
DBA/2J both 0.2209 0.0347 0.289 0.1527
FVB/NJ both 0.1297 0.0378 0.204 0.0553
I/LnJ both 0.2131 0.0428 0.2972 0.129
KK/HlJ both 0.2392 0.0395 0.3168 0.1616
LP/J both -0.0646 0.0365 0.0073 -0.1364
NOD/ShiLtJ both 0.2264 0.0365 0.2982 0.1545
NON/ShiLtJ both 0.0522 0.0365 0.124 -0.0197
NZW/LacJ both 0.1153 0.0365 0.1872 0.0435
PL/J both -0.0157 0.0365 0.0562 -0.0875
RIIIS/J both 0.1512 0.0365 0.223 0.0793
SJL/J both 0.0236 0.0365 0.0955 -0.0482
SM/J both 0.207 0.0365 0.2788 0.1352
SWR/J both 0.1542 0.0355 0.224 0.0844




  GWAS USING LINEAR MIXED MODELS