Phenotype measure:   Berndt2   tidal_vol_mch20


  STRAIN COMPARISON PLOT
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Berndt2 - tidal volume 20 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.288   mL 0.324   mL
Median of the strain means0.287   mL 0.316   mL
SD of the strain means± 0.0742 ± 0.0733
Coefficient of variation (CV)0.258 0.226
Min–max range of strain means0.150   –   0.511   mL 0.181   –   0.512   mL
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1482 0.1482 60.0549 < 0.0001
strain 28 2.2457 0.0802 32.4951 < 0.0001
sex:strain 28 0.171 0.0061 2.4737 0.0001
Residuals 412 1.0169 0.0025


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.359 0.0974   8 0.0345 0.272 0.234, 0.529 0.96
129S1/SvImJ m 0.359 0.105   8 0.0372 0.293 0.241, 0.551 0.48
A/J f 0.276 0.0405   8 0.0143 0.147 0.195, 0.32 -0.16
A/J m 0.316 0.0263   8 0.0093 0.0834 0.27, 0.35 -0.11
AKR/J f 0.326 0.0484   8 0.0171 0.148 0.273, 0.416 0.52
AKR/J m 0.404 0.0771   8 0.0273 0.191 0.294, 0.533 1.09
BALB/cByJ f 0.288 0.0364   8 0.0129 0.126 0.226, 0.348 0.0
BALB/cByJ m 0.295 0.046   8 0.0163 0.156 0.213, 0.349 -0.4
BALB/cJ f 0.27 0.0222   10 0.00702 0.0824 0.241, 0.312 -0.24
BALB/cJ m 0.291 0.0404   10 0.0128 0.139 0.211, 0.347 -0.45
BTBR T+ Itpr3tf/J f 0.511 0.0891   8 0.0315 0.174 0.388, 0.644 3.01
BTBR T+ Itpr3tf/J m 0.512 0.0624   8 0.0221 0.122 0.395, 0.599 2.57
BUB/BnJ f 0.368 0.0382   7 0.0144 0.104 0.309, 0.435 1.08
BUB/BnJ m 0.394 0.0257   8 0.00908 0.0653 0.345, 0.42 0.96
C3H/HeJ f 0.267 0.0316   8 0.0112 0.119 0.219, 0.315 -0.28
C3H/HeJ m 0.306 0.0979   8 0.0346 0.32 0.199, 0.514 -0.25
C57BL/10J f 0.327 0.0288   8 0.0102 0.0883 0.273, 0.358 0.53
C57BL/10J m 0.398 0.017   7 0.00644 0.0428 0.363, 0.415 1.01
C57BL/6J f 0.314 0.0515   7 0.0195 0.164 0.245, 0.39 0.36
C57BL/6J m 0.366 0.0644   13 0.0179 0.176 0.217, 0.448 0.57
C57BLKS/J f 0.314 0.0725   11 0.0219 0.231 0.191, 0.425 0.36
C57BLKS/J m 0.379 0.0752   8 0.0266 0.198 0.322, 0.542 0.75
C57BR/cdJ f 0.365 0.052   6 0.0212 0.142 0.283, 0.428 1.04
C57BR/cdJ m 0.386 0.069   8 0.0244 0.179 0.275, 0.458 0.85
C57L/J f 0.314 0.0515   8 0.0182 0.164 0.236, 0.401 0.36
C57L/J m 0.392 0.029   8 0.0102 0.0739 0.357, 0.436 0.93
CBA/J f 0.358 0.0406   8 0.0144 0.114 0.289, 0.43 0.95
CBA/J m 0.373 0.0404   8 0.0143 0.108 0.314, 0.435 0.67
CE/J f 0.228 0.0366   8 0.0129 0.161 0.178, 0.281 -0.8
CE/J m 0.255 0.0485   9 0.0162 0.19 0.164, 0.319 -0.94
DBA/1J f 0.297 0.0509   10 0.0161 0.171 0.227, 0.386 0.13
DBA/1J m 0.338 0.0561   8 0.0198 0.166 0.24, 0.414 0.19
DBA/2J f 0.265 0.0367   8 0.013 0.139 0.226, 0.343 -0.31
DBA/2J m 0.29 0.0339   10 0.0107 0.117 0.219, 0.331 -0.46
FVB/NJ f 0.238 0.054   8 0.0191 0.227 0.168, 0.303 -0.67
FVB/NJ m 0.378 0.0574   7 0.0217 0.152 0.263, 0.438 0.74
I/LnJ f 0.257 0.0352   7 0.0133 0.137 0.216, 0.306 -0.41
I/LnJ m 0.362 0.0641   5 0.0287 0.177 0.251, 0.414 0.52
KK/HlJ f 0.368 0.0344   8 0.0122 0.0936 0.334, 0.415 1.08
KK/HlJ m 0.362 0.0268   6 0.0109 0.0739 0.331, 0.396 0.52
LP/J f 0.15 0.0304   8 0.0107 0.202 0.104, 0.199 -1.86
LP/J m 0.2 0.0377   8 0.0133 0.188 0.164, 0.287 -1.69
NOD/ShiLtJ f 0.316 0.0506   8 0.0179 0.16 0.237, 0.392 0.38
NOD/ShiLtJ m 0.29 0.0228   8 0.00807 0.0788 0.268, 0.335 -0.46
NON/ShiLtJ f 0.263 0.0287   8 0.0102 0.109 0.233, 0.321 -0.33
NON/ShiLtJ m 0.259 0.0265   8 0.00939 0.103 0.215, 0.294 -0.89
NZW/LacJ f 0.287 0.0289   8 0.0102 0.101 0.254, 0.339 -0.01
NZW/LacJ m 0.275 0.0507   8 0.0179 0.184 0.179, 0.35 -0.67
PL/J f 0.168 0.0234   8 0.00828 0.139 0.14, 0.211 -1.61
PL/J m 0.212 0.0497   8 0.0176 0.235 0.166, 0.295 -1.53
RIIIS/J f 0.24 0.025   8 0.00883 0.104 0.189, 0.274 -0.64
RIIIS/J m 0.227 0.0471   8 0.0166 0.207 0.157, 0.293 -1.32
SJL/J f 0.171 0.0304   8 0.0108 0.178 0.14, 0.225 -1.57
SJL/J m 0.181 0.0242   8 0.00855 0.134 0.164, 0.238 -1.95
SM/J f 0.247 0.0331   8 0.0117 0.134 0.208, 0.301 -0.55
SM/J m 0.293 0.0452   8 0.016 0.154 0.255, 0.367 -0.42
SWR/J f 0.19 0.0151   8 0.00535 0.0796 0.163, 0.208 -1.32
SWR/J m 0.302 0.0331   9 0.011 0.11 0.261, 0.362 -0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3586 0.0176 0.3932 0.3241
129S1/SvImJ m 0.3589 0.0176 0.3934 0.3243
A/J f 0.2759 0.0176 0.3104 0.2413
A/J m 0.3155 0.0176 0.35 0.281
AKR/J f 0.326 0.0176 0.3605 0.2915
AKR/J m 0.4035 0.0176 0.438 0.369
BALB/cByJ f 0.2879 0.0176 0.3224 0.2533
BALB/cByJ m 0.2947 0.0176 0.3293 0.2602
BALB/cJ f 0.2697 0.0157 0.3006 0.2388
BALB/cJ m 0.2913 0.0157 0.3222 0.2604
BTBR T+ Itpr3tf/J f 0.511 0.0176 0.5455 0.4765
BTBR T+ Itpr3tf/J m 0.5116 0.0176 0.5462 0.4771
BUB/BnJ f 0.3681 0.0188 0.4051 0.3312
BUB/BnJ m 0.3936 0.0176 0.4282 0.3591
C3H/HeJ f 0.267 0.0176 0.3015 0.2325
C3H/HeJ m 0.3064 0.0176 0.3409 0.2718
C57BL/10J f 0.3266 0.0176 0.3612 0.2921
C57BL/10J m 0.3976 0.0188 0.4345 0.3607
C57BL/6J f 0.3137 0.0188 0.3506 0.2768
C57BL/6J m 0.3656 0.0138 0.3927 0.3385
C57BLKS/J f 0.3143 0.015 0.3437 0.2848
C57BLKS/J m 0.3791 0.0176 0.4137 0.3446
C57BR/cdJ f 0.3655 0.0203 0.4054 0.3256
C57BR/cdJ m 0.3862 0.0176 0.4208 0.3517
C57L/J f 0.3135 0.0176 0.348 0.279
C57L/J m 0.3925 0.0176 0.427 0.358
CBA/J f 0.3576 0.0176 0.3922 0.3231
CBA/J m 0.3734 0.0176 0.4079 0.3388
CE/J f 0.228 0.0176 0.2625 0.1935
CE/J m 0.2553 0.0166 0.2879 0.2228
DBA/1J f 0.2971 0.0157 0.328 0.2662
DBA/1J m 0.3377 0.0176 0.3723 0.3032
DBA/2J f 0.2646 0.0176 0.2992 0.2301
DBA/2J m 0.2898 0.0157 0.3207 0.2589
FVB/NJ f 0.2382 0.0176 0.2728 0.2037
FVB/NJ m 0.3776 0.0188 0.4145 0.3407
I/LnJ f 0.2574 0.0188 0.2943 0.2205
I/LnJ m 0.3616 0.0222 0.4053 0.3179
KK/HlJ f 0.3679 0.0176 0.4024 0.3333
KK/HlJ m 0.3622 0.0203 0.402 0.3223
LP/J f 0.1505 0.0176 0.185 0.116
LP/J m 0.2002 0.0176 0.2348 0.1657
NOD/ShiLtJ f 0.3159 0.0176 0.3504 0.2813
NOD/ShiLtJ m 0.2896 0.0176 0.3242 0.2551
NON/ShiLtJ f 0.263 0.0176 0.2975 0.2285
NON/ShiLtJ m 0.2586 0.0176 0.2932 0.2241
NZW/LacJ f 0.2874 0.0176 0.3219 0.2528
NZW/LacJ m 0.275 0.0176 0.3095 0.2405
PL/J f 0.1683 0.0176 0.2028 0.1337
PL/J m 0.2118 0.0176 0.2463 0.1772
RIIIS/J f 0.2401 0.0176 0.2747 0.2056
RIIIS/J m 0.227 0.0176 0.2615 0.1925
SJL/J f 0.1705 0.0176 0.205 0.136
SJL/J m 0.1806 0.0176 0.2152 0.1461
SM/J f 0.2475 0.0176 0.282 0.213
SM/J m 0.293 0.0176 0.3275 0.2585
SWR/J f 0.19 0.0176 0.2245 0.1555
SWR/J m 0.3017 0.0166 0.3342 0.2691


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3587 0.0124 0.3832 0.3343
A/J both 0.2957 0.0124 0.3201 0.2713
AKR/J both 0.3648 0.0124 0.3892 0.3403
BALB/cByJ both 0.2913 0.0124 0.3157 0.2669
BALB/cJ both 0.2805 0.0111 0.3023 0.2587
BTBR T+ Itpr3tf/J both 0.5113 0.0124 0.5357 0.4869
BUB/BnJ both 0.3809 0.0129 0.4062 0.3556
C3H/HeJ both 0.2867 0.0124 0.3111 0.2623
C57BL/10J both 0.3621 0.0129 0.3874 0.3368
C57BL/6J both 0.3397 0.0116 0.3626 0.3168
C57BLKS/J both 0.3467 0.0115 0.3694 0.324
C57BR/cdJ both 0.3759 0.0134 0.4022 0.3495
C57L/J both 0.353 0.0124 0.3774 0.3286
CBA/J both 0.3655 0.0124 0.3899 0.3411
CE/J both 0.2417 0.0121 0.2654 0.2179
DBA/1J both 0.3174 0.0118 0.3406 0.2943
DBA/2J both 0.2772 0.0118 0.3004 0.2541
FVB/NJ both 0.3079 0.0129 0.3332 0.2826
I/LnJ both 0.3095 0.0145 0.3381 0.2809
KK/HlJ both 0.365 0.0134 0.3914 0.3387
LP/J both 0.1754 0.0124 0.1998 0.151
NOD/ShiLtJ both 0.3027 0.0124 0.3272 0.2783
NON/ShiLtJ both 0.2608 0.0124 0.2852 0.2364
NZW/LacJ both 0.2812 0.0124 0.3056 0.2568
PL/J both 0.19 0.0124 0.2144 0.1656
RIIIS/J both 0.2336 0.0124 0.258 0.2091
SJL/J both 0.1756 0.0124 0.2 0.1511
SM/J both 0.2702 0.0124 0.2947 0.2458
SWR/J both 0.2458 0.0121 0.2696 0.2221




  GWAS USING LINEAR MIXED MODELS