Project measure / variable:   Berndt2   penh_mch10

ID, description, units MPD:35163   penh_mch10   enhanced pause    10 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - enhanced pause 10 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means2.24   None 2.93   None
Median of the strain means1.74   None 2.08   None
SD of the strain means± 1.36 ± 1.80
Coefficient of variation (CV)0.605 0.614
Min–max range of strain means0.773   –   5.88   None 0.821   –   6.42   None
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 44.9993 44.9993 22.8055 < 0.0001
strain 28 894.6239 31.9509 16.1926 < 0.0001
sex:strain 28 214.8044 7.6716 3.8879 < 0.0001
Residuals 412 812.9484 1.9732


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.23 0.839   8 0.297 0.377 1.29, 3.43 -0.01
129S1/SvImJ m 5.48 3.75   8 1.32 0.683 1.22, 12.1 1.42
A/J f 4.85 2.04   8 0.72 0.42 2.96, 9.11 1.92
A/J m 5.42 2.64   8 0.934 0.488 2.48, 9.67 1.39
AKR/J f 3.2 1.04   8 0.367 0.325 1.45, 4.56 0.7
AKR/J m 5.28 1.09   8 0.386 0.207 3.92, 7.37 1.31
BALB/cByJ f 1.73 0.689   8 0.244 0.397 0.939, 2.67 -0.38
BALB/cByJ m 0.821 0.168   8 0.0594 0.205 0.52, 1.0 -1.17
BALB/cJ f 1.74 1.0   10 0.317 0.578 0.681, 4.32 -0.37
BALB/cJ m 1.69 0.346   10 0.109 0.205 1.23, 2.42 -0.69
BTBR T+ Itpr3tf/J f 5.88 2.92   8 1.03 0.496 2.42, 10.4 2.68
BTBR T+ Itpr3tf/J m 6.42 1.4   8 0.495 0.218 4.28, 8.66 1.94
BUB/BnJ f 3.5 1.19   7 0.449 0.34 2.37, 5.79 0.92
BUB/BnJ m 4.28 0.643   8 0.227 0.15 3.39, 5.47 0.75
C3H/HeJ f 1.22 0.188   8 0.0664 0.154 0.973, 1.55 -0.75
C3H/HeJ m 1.7 0.434   8 0.153 0.256 1.12, 2.22 -0.68
C57BL/10J f 1.15 0.333   8 0.118 0.289 0.727, 1.62 -0.81
C57BL/10J m 1.9 0.673   7 0.254 0.355 1.04, 2.8 -0.57
C57BL/6J f 2.11 0.874   7 0.33 0.413 1.47, 3.4 -0.1
C57BL/6J m 1.85 0.702   13 0.195 0.379 0.97, 3.39 -0.6
C57BLKS/J f 0.773 0.314   11 0.0946 0.406 0.49, 1.57 -1.08
C57BLKS/J m 2.2 1.29   8 0.457 0.587 1.1, 4.86 -0.4
C57BR/cdJ f 1.06 0.298   6 0.122 0.282 0.718, 1.47 -0.87
C57BR/cdJ m 1.02 0.454   8 0.161 0.445 0.62, 2.05 -1.06
C57L/J f 0.998 0.335   8 0.119 0.336 0.58, 1.54 -0.92
C57L/J m 2.05 0.982   8 0.347 0.478 0.994, 3.96 -0.49
CBA/J f 2.13 0.546   8 0.193 0.256 1.28, 3.09 -0.08
CBA/J m 3.86 0.929   8 0.329 0.241 2.4, 5.62 0.52
CE/J f 0.952 0.317   8 0.112 0.333 0.55, 1.49 -0.95
CE/J m 0.882 0.42   9 0.14 0.477 0.47, 1.8 -1.14
DBA/1J f 1.28 0.204   10 0.0644 0.159 0.95, 1.6 -0.71
DBA/1J m 6.0 3.16   8 1.12 0.527 2.97, 13.0 1.71
DBA/2J f 1.72 0.598   8 0.211 0.348 1.0, 2.65 -0.39
DBA/2J m 2.18 1.19   10 0.375 0.543 0.83, 5.08 -0.42
FVB/NJ f 1.42 0.412   8 0.146 0.291 0.932, 2.23 -0.61
FVB/NJ m 3.55 1.01   7 0.383 0.285 1.76, 4.61 0.35
I/LnJ f 4.32 5.07   7 1.91 1.17 1.11, 15.3 1.53
I/LnJ m 6.12 3.92   5 1.75 0.64 3.03, 12.9 1.78
KK/HlJ f 5.22 1.33   8 0.471 0.255 3.73, 7.76 2.19
KK/HlJ m 4.77 2.83   6 1.16 0.593 1.14, 7.12 1.03
LP/J f 1.3 0.434   8 0.153 0.333 0.879, 1.97 -0.7
LP/J m 0.981 0.394   8 0.139 0.402 0.52, 1.71 -1.08
NOD/ShiLtJ f 1.62 0.79   8 0.279 0.488 0.602, 2.73 -0.46
NOD/ShiLtJ m 1.35 0.352   8 0.124 0.261 0.867, 1.87 -0.88
NON/ShiLtJ f 2.85 1.75   8 0.618 0.613 1.52, 6.25 0.45
NON/ShiLtJ m 1.51 0.476   8 0.168 0.316 0.886, 2.26 -0.79
NZW/LacJ f 3.26 1.82   8 0.645 0.559 1.22, 6.69 0.75
NZW/LacJ m 1.81 0.975   8 0.345 0.539 0.78, 3.71 -0.62
PL/J f 1.48 0.359   8 0.127 0.243 1.05, 2.02 -0.56
PL/J m 1.5 0.682   8 0.241 0.456 0.652, 2.86 -0.79
RIIIS/J f 2.12 0.54   8 0.191 0.255 1.28, 2.76 -0.09
RIIIS/J m 1.79 1.07   8 0.378 0.596 0.893, 3.71 -0.63
SJL/J f 1.78 0.506   8 0.179 0.285 0.951, 2.62 -0.34
SJL/J m 2.61 0.691   8 0.244 0.265 1.9, 3.95 -0.18
SM/J f 1.89 0.536   8 0.19 0.283 1.31, 2.83 -0.26
SM/J m 2.08 1.12   8 0.394 0.536 1.15, 4.07 -0.47
SWR/J f 1.31 0.331   8 0.117 0.252 0.831, 1.74 -0.69
SWR/J m 3.78 1.49   9 0.495 0.394 1.69, 5.96 0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.2275 0.4966 3.2038 1.2512
129S1/SvImJ m 5.4825 0.4966 6.4588 4.5062
A/J f 4.8462 0.4966 5.8225 3.87
A/J m 5.4188 0.4966 6.395 4.4425
AKR/J f 3.1963 0.4966 4.1725 2.22
AKR/J m 5.2763 0.4966 6.2525 4.3
BALB/cByJ f 1.7336 0.4966 2.7099 0.7574
BALB/cByJ m 0.8212 0.4966 1.7975 0.0
BALB/cJ f 1.7351 0.4442 2.6083 0.8619
BALB/cJ m 1.688 0.4442 2.5612 0.8148
BTBR T+ Itpr3tf/J f 5.8812 0.4966 6.8575 4.905
BTBR T+ Itpr3tf/J m 6.4163 0.4966 7.3925 5.44
BUB/BnJ f 3.4957 0.5309 4.5394 2.4521
BUB/BnJ m 4.2775 0.4966 5.2538 3.3012
C3H/HeJ f 1.2191 0.4966 2.1954 0.2429
C3H/HeJ m 1.6962 0.4966 2.6725 0.72
C57BL/10J f 1.1528 0.4966 2.129 0.1765
C57BL/10J m 1.8957 0.5309 2.9394 0.8521
C57BL/6J f 2.1143 0.5309 3.1579 1.0706
C57BL/6J m 1.8546 0.3896 2.6205 1.0888
C57BLKS/J f 0.7733 0.4235 1.6058 0.0
C57BLKS/J m 2.1988 0.4966 3.175 1.2225
C57BR/cdJ f 1.059 0.5735 2.1863 0.0
C57BR/cdJ m 1.0196 0.4966 1.9959 0.0434
C57L/J f 0.9977 0.4966 1.974 0.0215
C57L/J m 2.053 0.4966 3.0293 1.0767
CBA/J f 2.1275 0.4966 3.1038 1.1512
CBA/J m 3.86 0.4966 4.8363 2.8837
CE/J f 0.9515 0.4966 1.9278 0.0
CE/J m 0.8822 0.4682 1.8026 0.0
DBA/1J f 1.277 0.4442 2.1502 0.4038
DBA/1J m 6.005 0.4966 6.9813 5.0287
DBA/2J f 1.72 0.4966 2.6963 0.7437
DBA/2J m 2.185 0.4442 3.0582 1.3118
FVB/NJ f 1.4177 0.4966 2.394 0.4415
FVB/NJ m 3.5529 0.5309 4.5965 2.5092
I/LnJ f 4.3186 0.5309 5.3622 3.2749
I/LnJ m 6.122 0.6282 7.3569 4.8871
KK/HlJ f 5.2163 0.4966 6.1925 4.24
KK/HlJ m 4.7733 0.5735 5.9006 3.6461
LP/J f 1.3016 0.4966 2.2779 0.3254
LP/J m 0.9812 0.4966 1.9575 0.005
NOD/ShiLtJ f 1.6201 0.4966 2.5964 0.6439
NOD/ShiLtJ m 1.3471 0.4966 2.3234 0.3709
NON/ShiLtJ f 2.855 0.4966 3.8313 1.8787
NON/ShiLtJ m 1.5082 0.4966 2.4845 0.532
NZW/LacJ f 3.265 0.4966 4.2413 2.2887
NZW/LacJ m 1.8087 0.4966 2.785 0.8325
PL/J f 1.475 0.4966 2.4513 0.4987
PL/J m 1.4973 0.4966 2.4735 0.521
RIIIS/J f 2.115 0.4966 3.0913 1.1387
RIIIS/J m 1.7916 0.4966 2.7679 0.8154
SJL/J f 1.7751 0.4966 2.7514 0.7989
SJL/J m 2.6062 0.4966 3.5825 1.63
SM/J f 1.8925 0.4966 2.8688 0.9162
SM/J m 2.0812 0.4966 3.0575 1.105
SWR/J f 1.3103 0.4966 2.2865 0.334
SWR/J m 3.7756 0.4682 4.696 2.8551


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.855 0.3512 4.5453 3.1647
A/J both 5.1325 0.3512 5.8228 4.4422
AKR/J both 4.2363 0.3512 4.9266 3.5459
BALB/cByJ both 1.2774 0.3512 1.9678 0.5871
BALB/cJ both 1.7115 0.3141 2.329 1.0941
BTBR T+ Itpr3tf/J both 6.1488 0.3512 6.8391 5.4584
BUB/BnJ both 3.8866 0.3635 4.6012 3.1721
C3H/HeJ both 1.4577 0.3512 2.148 0.7674
C57BL/10J both 1.5242 0.3635 2.2388 0.8097
C57BL/6J both 1.9845 0.3293 2.6317 1.3372
C57BLKS/J both 1.486 0.3264 2.1275 0.8445
C57BR/cdJ both 1.0393 0.3793 1.7849 0.2937
C57L/J both 1.5254 0.3512 2.2157 0.8351
CBA/J both 2.9938 0.3512 3.6841 2.3034
CE/J both 0.9169 0.3413 1.5877 0.246
DBA/1J both 3.641 0.3332 4.2959 2.9861
DBA/2J both 1.9525 0.3332 2.6074 1.2976
FVB/NJ both 2.4853 0.3635 3.1998 1.7708
I/LnJ both 5.2203 0.4113 6.0287 4.4119
KK/HlJ both 4.9948 0.3793 5.7404 4.2492
LP/J both 1.1414 0.3512 1.8318 0.4511
NOD/ShiLtJ both 1.4836 0.3512 2.1739 0.7933
NON/ShiLtJ both 2.1816 0.3512 2.8719 1.4913
NZW/LacJ both 2.5369 0.3512 3.2272 1.8466
PL/J both 1.4861 0.3512 2.1764 0.7958
RIIIS/J both 1.9533 0.3512 2.6436 1.263
SJL/J both 2.1907 0.3512 2.881 1.5004
SM/J both 1.9869 0.3512 2.6772 1.2966
SWR/J both 2.5429 0.3413 3.2138 1.872




  GWAS USING LINEAR MIXED MODELS