Project measure / variable:   Berndt2   penh_saline

ID, description, units MPD:35161   penh_saline   enhanced pause    saline  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - enhanced pause saline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.825   None 0.751   None
Median of the strain means0.805   None 0.736   None
SD of the strain means± 0.183 ± 0.221
Coefficient of variation (CV)0.223 0.294
Min–max range of strain means0.543   –   1.20   None 0.373   –   1.28   None
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.6434 0.6434 7.497 0.0064
strain 28 15.0725 0.5383 6.2723 < 0.0001
sex:strain 28 3.7986 0.1357 1.5808 0.0322
Residuals 412 35.359 0.0858


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.632 0.159   8 0.0563 0.252 0.419, 0.899 -1.05
129S1/SvImJ m 0.645 0.172   8 0.0608 0.267 0.401, 0.88 -0.48
A/J f 0.709 0.151   8 0.0534 0.213 0.563, 1.02 -0.63
A/J m 0.769 0.127   8 0.045 0.165 0.599, 1.02 0.08
AKR/J f 0.905 0.392   8 0.138 0.433 0.588, 1.74 0.44
AKR/J m 0.972 0.384   8 0.136 0.395 0.435, 1.49 1.0
BALB/cByJ f 0.855 0.271   8 0.0958 0.317 0.375, 1.18 0.17
BALB/cByJ m 0.499 0.148   8 0.0523 0.296 0.27, 0.74 -1.14
BALB/cJ f 1.02 0.513   10 0.162 0.504 0.318, 1.97 1.06
BALB/cJ m 0.846 0.303   10 0.0958 0.358 0.492, 1.48 0.43
BTBR T+ Itpr3tf/J f 0.785 0.16   8 0.0565 0.204 0.561, 1.01 -0.22
BTBR T+ Itpr3tf/J m 0.664 0.249   8 0.088 0.375 0.415, 1.19 -0.4
BUB/BnJ f 0.846 0.294   7 0.111 0.348 0.504, 1.34 0.12
BUB/BnJ m 0.911 0.17   8 0.0601 0.187 0.679, 1.13 0.72
C3H/HeJ f 0.677 0.276   8 0.0977 0.408 0.472, 1.16 -0.8
C3H/HeJ m 0.804 0.245   8 0.0866 0.305 0.527, 1.21 0.24
C57BL/10J f 1.04 0.547   8 0.193 0.524 0.564, 1.92 1.17
C57BL/10J m 0.521 0.235   7 0.089 0.452 0.137, 0.808 -1.04
C57BL/6J f 0.648 0.161   7 0.0607 0.248 0.354, 0.822 -0.96
C57BL/6J m 0.596 0.208   13 0.0578 0.35 0.362, 0.948 -0.7
C57BLKS/J f 0.718 0.295   11 0.0891 0.412 0.41, 1.36 -0.58
C57BLKS/J m 0.479 0.184   8 0.0649 0.383 0.316, 0.863 -1.23
C57BR/cdJ f 0.83 0.387   6 0.158 0.467 0.393, 1.39 0.03
C57BR/cdJ m 0.509 0.147   8 0.0521 0.289 0.352, 0.74 -1.1
C57L/J f 0.543 0.096   8 0.0339 0.177 0.419, 0.687 -1.53
C57L/J m 0.437 0.112   8 0.0395 0.256 0.321, 0.639 -1.42
CBA/J f 0.833 0.304   8 0.108 0.366 0.484, 1.42 0.05
CBA/J m 0.727 0.222   8 0.0785 0.306 0.405, 1.09 -0.11
CE/J f 0.583 0.604   8 0.214 1.04 0.252, 2.06 -1.32
CE/J m 0.373 0.136   9 0.0453 0.364 0.18, 0.61 -1.71
DBA/1J f 0.805 0.41   10 0.13 0.51 0.45, 1.9 -0.11
DBA/1J m 0.834 0.269   8 0.0952 0.323 0.516, 1.16 0.37
DBA/2J f 0.76 0.249   8 0.0879 0.327 0.426, 1.08 -0.35
DBA/2J m 0.977 0.465   10 0.147 0.476 0.551, 1.97 1.02
FVB/NJ f 0.9 0.227   8 0.0801 0.252 0.664, 1.31 0.41
FVB/NJ m 0.736 0.132   7 0.05 0.18 0.569, 0.994 -0.07
I/LnJ f 0.737 0.19   7 0.072 0.258 0.52, 1.08 -0.48
I/LnJ m 0.686 0.0519   5 0.0232 0.0756 0.609, 0.75 -0.3
KK/HlJ f 0.803 0.368   8 0.13 0.458 0.502, 1.66 -0.12
KK/HlJ m 0.796 0.157   6 0.0641 0.197 0.574, 1.0 0.2
LP/J f 0.754 0.159   8 0.0561 0.21 0.528, 1.05 -0.39
LP/J m 0.64 0.106   8 0.0374 0.165 0.48, 0.77 -0.5
NOD/ShiLtJ f 0.549 0.211   8 0.0747 0.385 0.153, 0.818 -1.5
NOD/ShiLtJ m 0.602 0.173   8 0.0611 0.287 0.384, 0.875 -0.68
NON/ShiLtJ f 1.2 0.461   8 0.163 0.384 0.729, 1.84 2.05
NON/ShiLtJ m 0.75 0.16   8 0.0567 0.214 0.587, 1.02 -0.01
NZW/LacJ f 0.834 0.308   8 0.109 0.369 0.509, 1.52 0.05
NZW/LacJ m 1.02 0.362   8 0.128 0.355 0.58, 1.66 1.22
PL/J f 1.18 0.318   8 0.112 0.27 0.857, 1.82 1.94
PL/J m 1.17 0.251   8 0.0889 0.214 0.813, 1.54 1.89
RIIIS/J f 1.13 0.471   8 0.166 0.417 0.681, 2.08 1.66
RIIIS/J m 1.03 0.288   8 0.102 0.28 0.71, 1.5 1.26
SJL/J f 1.04 0.324   8 0.115 0.312 0.728, 1.58 1.17
SJL/J m 1.28 0.521   8 0.184 0.407 0.712, 2.41 2.39
SM/J f 0.589 0.125   8 0.0443 0.213 0.401, 0.727 -1.28
SM/J m 0.614 0.234   8 0.0828 0.381 0.22, 0.964 -0.62
SWR/J f 1.01 0.319   8 0.113 0.317 0.718, 1.59 1.01
SWR/J m 0.904 0.145   9 0.0485 0.161 0.722, 1.16 0.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6316 0.1036 0.8352 0.428
129S1/SvImJ m 0.6447 0.1036 0.8484 0.4411
A/J f 0.7095 0.1036 0.9131 0.5059
A/J m 0.7689 0.1036 0.9725 0.5653
AKR/J f 0.9049 0.1036 1.1085 0.7013
AKR/J m 0.9716 0.1036 1.1752 0.768
BALB/cByJ f 0.8553 0.1036 1.0589 0.6516
BALB/cByJ m 0.4987 0.1036 0.7024 0.2951
BALB/cJ f 1.0177 0.0926 1.1998 0.8356
BALB/cJ m 0.8463 0.0926 1.0284 0.6642
BTBR T+ Itpr3tf/J f 0.7849 0.1036 0.9885 0.5813
BTBR T+ Itpr3tf/J m 0.6638 0.1036 0.8674 0.4601
BUB/BnJ f 0.8459 0.1107 1.0635 0.6282
BUB/BnJ m 0.9107 0.1036 1.1144 0.7071
C3H/HeJ f 0.6773 0.1036 0.8809 0.4736
C3H/HeJ m 0.8039 0.1036 1.0075 0.6003
C57BL/10J f 1.0441 0.1036 1.2477 0.8405
C57BL/10J m 0.5213 0.1107 0.7389 0.3036
C57BL/6J f 0.6477 0.1107 0.8654 0.4301
C57BL/6J m 0.5955 0.0813 0.7553 0.4358
C57BLKS/J f 0.7176 0.0883 0.8913 0.544
C57BLKS/J m 0.4795 0.1036 0.6831 0.2759
C57BR/cdJ f 0.83 0.1196 1.0651 0.5949
C57BR/cdJ m 0.509 0.1036 0.7126 0.3054
C57L/J f 0.543 0.1036 0.7466 0.3394
C57L/J m 0.4372 0.1036 0.6409 0.2336
CBA/J f 0.8329 0.1036 1.0365 0.6293
CBA/J m 0.7267 0.1036 0.9304 0.5231
CE/J f 0.5828 0.1036 0.7864 0.3791
CE/J m 0.3733 0.0977 0.5653 0.1814
DBA/1J f 0.805 0.0926 0.9871 0.6229
DBA/1J m 0.8339 0.1036 1.0375 0.6303
DBA/2J f 0.7595 0.1036 0.9631 0.5559
DBA/2J m 0.9775 0.0926 1.1596 0.7954
FVB/NJ f 0.9005 0.1036 1.1041 0.6969
FVB/NJ m 0.7364 0.1107 0.9541 0.5188
I/LnJ f 0.7369 0.1107 0.9545 0.5192
I/LnJ m 0.6862 0.131 0.9437 0.4287
KK/HlJ f 0.8031 0.1036 1.0067 0.5995
KK/HlJ m 0.7962 0.1196 1.0313 0.5611
LP/J f 0.7543 0.1036 0.9579 0.5506
LP/J m 0.6401 0.1036 0.8437 0.4365
NOD/ShiLtJ f 0.5489 0.1036 0.7525 0.3453
NOD/ShiLtJ m 0.6023 0.1036 0.8059 0.3986
NON/ShiLtJ f 1.1986 0.1036 1.4022 0.995
NON/ShiLtJ m 0.7503 0.1036 0.9539 0.5466
NZW/LacJ f 0.8345 0.1036 1.0381 0.6309
NZW/LacJ m 1.0188 0.1036 1.2224 0.8151
PL/J f 1.1775 0.1036 1.3811 0.9739
PL/J m 1.1737 0.1036 1.3774 0.9701
RIIIS/J f 1.128 0.1036 1.3316 0.9244
RIIIS/J m 1.0294 0.1036 1.233 0.8258
SJL/J f 1.0388 0.1036 1.2424 0.8351
SJL/J m 1.2804 0.1036 1.484 1.0768
SM/J f 0.5889 0.1036 0.7925 0.3853
SM/J m 0.6143 0.1036 0.8179 0.4106
SWR/J f 1.0078 0.1036 1.2114 0.8041
SWR/J m 0.9041 0.0977 1.0961 0.7122


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.6382 0.0732 0.7822 0.4942
A/J both 0.7392 0.0732 0.8832 0.5952
AKR/J both 0.9382 0.0732 1.0822 0.7943
BALB/cByJ both 0.677 0.0732 0.821 0.533
BALB/cJ both 0.932 0.0655 1.0608 0.8032
BTBR T+ Itpr3tf/J both 0.7243 0.0732 0.8683 0.5803
BUB/BnJ both 0.8783 0.0758 1.0273 0.7293
C3H/HeJ both 0.7406 0.0732 0.8845 0.5966
C57BL/10J both 0.7827 0.0758 0.9317 0.6337
C57BL/6J both 0.6216 0.0687 0.7566 0.4866
C57BLKS/J both 0.5986 0.0681 0.7324 0.4648
C57BR/cdJ both 0.6695 0.0791 0.825 0.514
C57L/J both 0.4901 0.0732 0.6341 0.3462
CBA/J both 0.7798 0.0732 0.9238 0.6358
CE/J both 0.478 0.0712 0.618 0.3381
DBA/1J both 0.8194 0.0695 0.956 0.6829
DBA/2J both 0.8685 0.0695 1.0051 0.7319
FVB/NJ both 0.8185 0.0758 0.9675 0.6694
I/LnJ both 0.7115 0.0858 0.8801 0.5429
KK/HlJ both 0.7996 0.0791 0.9551 0.6441
LP/J both 0.6972 0.0732 0.8412 0.5532
NOD/ShiLtJ both 0.5756 0.0732 0.7195 0.4316
NON/ShiLtJ both 0.9744 0.0732 1.1184 0.8305
NZW/LacJ both 0.9266 0.0732 1.0706 0.7827
PL/J both 1.1756 0.0732 1.3196 1.0317
RIIIS/J both 1.0787 0.0732 1.2227 0.9347
SJL/J both 1.1596 0.0732 1.3035 1.0156
SM/J both 0.6016 0.0732 0.7455 0.4576
SWR/J both 0.9559 0.0712 1.0958 0.816




  GWAS USING LINEAR MIXED MODELS