Phenotype measure:   Berndt2   penh_slope


  STRAIN COMPARISON PLOT
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Berndt2 - enhanced pause response index



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.978   None 1.03   None
Median of the strain means1.04   None 1.04   None
SD of the strain means± 0.336 ± 0.426
Coefficient of variation (CV)0.343 0.414
Min–max range of strain means0.275   –   1.55   None 0.114   –   1.79   None
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3135 0.3135 1.9323 0.1653
strain 28 49.57 1.7704 10.9109 < 0.0001
sex:strain 28 16.5664 0.5917 3.6465 < 0.0001
Residuals 412 66.8494 0.1623


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.55 0.384   8 0.136 0.248 1.03, 2.16 1.7
129S1/SvImJ m 1.1 0.417   8 0.148 0.378 0.457, 1.72 0.16
A/J f 1.3 0.397   8 0.14 0.306 0.457, 1.74 0.96
A/J m 1.57 0.121   8 0.0427 0.077 1.38, 1.74 1.27
AKR/J f 1.13 0.307   8 0.108 0.271 0.724, 1.7 0.45
AKR/J m 0.747 0.361   8 0.128 0.483 0.182, 1.23 -0.66
BALB/cByJ f 0.829 0.5   8 0.177 0.603 0.019, 1.59 -0.44
BALB/cByJ m 0.642 0.267   8 0.0942 0.415 0.255, 1.02 -0.91
BALB/cJ f 0.799 0.302   10 0.0955 0.378 0.465, 1.47 -0.53
BALB/cJ m 0.915 0.183   10 0.058 0.201 0.537, 1.08 -0.27
BTBR T+ Itpr3tf/J f 1.54 0.264   8 0.0935 0.172 1.05, 1.99 1.67
BTBR T+ Itpr3tf/J m 1.51 0.309   8 0.109 0.204 1.11, 1.99 1.13
BUB/BnJ f 1.31 0.603   7 0.228 0.459 0.258, 2.08 0.99
BUB/BnJ m 1.41 0.3   8 0.106 0.213 0.842, 1.78 0.89
C3H/HeJ f 0.71 0.481   8 0.17 0.677 -0.133, 1.28 -0.8
C3H/HeJ m 0.784 0.59   8 0.208 0.752 -0.031, 1.53 -0.58
C57BL/10J f 0.723 0.471   8 0.166 0.651 0.25, 1.74 -0.76
C57BL/10J m 1.69 0.401   7 0.151 0.237 1.22, 2.23 1.55
C57BL/6J f 1.19 0.44   7 0.166 0.369 0.516, 1.77 0.63
C57BL/6J m 1.3 0.435   13 0.121 0.334 0.487, 1.96 0.63
C57BLKS/J f 1.14 0.53   11 0.16 0.463 0.037, 1.79 0.48
C57BLKS/J m 1.35 0.176   8 0.0623 0.13 1.12, 1.6 0.75
C57BR/cdJ f 0.805 0.452   6 0.185 0.562 0.197, 1.21 -0.52
C57BR/cdJ m 1.14 0.909   8 0.321 0.798 -0.124, 2.24 0.26
C57L/J f 1.11 0.395   8 0.14 0.356 0.6, 1.76 0.39
C57L/J m 1.55 0.468   8 0.166 0.301 0.8, 2.08 1.22
CBA/J f 1.26 0.117   8 0.0415 0.0934 1.08, 1.37 0.84
CBA/J m 1.04 0.102   8 0.036 0.0975 0.848, 1.18 0.02
CE/J f 1.04 0.4   8 0.141 0.385 0.532, 1.8 0.18
CE/J m 0.573 0.3   9 0.1 0.524 0.116, 1.17 -1.07
DBA/1J f 1.17 0.579   10 0.183 0.494 -0.067, 1.82 0.57
DBA/1J m 1.79 0.282   8 0.0997 0.157 1.37, 2.14 1.78
DBA/2J f 1.15 0.397   8 0.14 0.344 0.55, 1.67 0.51
DBA/2J m 1.06 0.496   10 0.157 0.468 0.113, 1.76 0.07
FVB/NJ f 0.615 0.418   8 0.148 0.68 -0.24, 1.11 -1.08
FVB/NJ m 1.03 0.323   7 0.122 0.315 0.552, 1.54 0.0
I/LnJ f 1.16 0.252   7 0.0954 0.217 0.782, 1.51 0.54
I/LnJ m 1.31 0.337   5 0.151 0.258 1.06, 1.88 0.66
KK/HlJ f 0.944 0.404   8 0.143 0.428 0.33, 1.49 -0.1
KK/HlJ m 0.834 0.384   6 0.157 0.46 0.489, 1.57 -0.46
LP/J f 0.275 0.417   8 0.147 1.52 -0.152, 0.953 -2.09
LP/J m 0.323 0.505   8 0.179 1.57 -0.351, 1.11 -1.66
NOD/ShiLtJ f 0.904 0.317   8 0.112 0.351 0.381, 1.36 -0.22
NOD/ShiLtJ m 0.883 0.351   8 0.124 0.398 0.399, 1.4 -0.34
NON/ShiLtJ f 0.514 0.367   8 0.13 0.714 -0.033, 1.2 -1.38
NON/ShiLtJ m 0.509 0.285   8 0.101 0.56 0.141, 1.02 -1.22
NZW/LacJ f 1.42 0.402   8 0.142 0.283 0.91, 1.98 1.32
NZW/LacJ m 0.672 0.374   8 0.132 0.556 0.177, 1.38 -0.84
PL/J f 0.442 0.221   8 0.0782 0.5 0.077, 0.709 -1.6
PL/J m 0.114 0.36   8 0.127 3.14 -0.177, 0.852 -2.15
RIIIS/J f 0.928 0.336   8 0.119 0.362 0.278, 1.27 -0.15
RIIIS/J m 0.673 0.559   8 0.198 0.831 -0.04, 1.33 -0.84
SJL/J f 0.605 0.359   8 0.127 0.592 -0.019, 1.26 -1.11
SJL/J m 0.599 0.285   8 0.101 0.476 0.161, 0.975 -1.01
SM/J f 1.29 0.224   8 0.0793 0.174 1.03, 1.64 0.93
SM/J m 1.33 0.364   8 0.129 0.273 0.658, 1.91 0.7
SWR/J f 0.512 0.524   8 0.185 1.02 -0.081, 1.27 -1.39
SWR/J m 1.42 0.429   9 0.143 0.302 0.557, 1.96 0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.5475 0.1424 1.8275 1.2675
129S1/SvImJ m 1.1029 0.1424 1.3828 0.8229
A/J f 1.2996 0.1424 1.5796 1.0197
A/J m 1.5688 0.1424 1.8487 1.2888
AKR/J f 1.1316 0.1424 1.4116 0.8517
AKR/J m 0.7473 0.1424 1.0272 0.4673
BALB/cByJ f 0.8293 0.1424 1.1092 0.5493
BALB/cByJ m 0.6416 0.1424 0.9216 0.3617
BALB/cJ f 0.799 0.1274 1.0494 0.5486
BALB/cJ m 0.9146 0.1274 1.165 0.6642
BTBR T+ Itpr3tf/J f 1.54 0.1424 1.82 1.26
BTBR T+ Itpr3tf/J m 1.5125 0.1424 1.7925 1.2325
BUB/BnJ f 1.3146 0.1522 1.6139 1.0153
BUB/BnJ m 1.4103 0.1424 1.6902 1.1303
C3H/HeJ f 0.7101 0.1424 0.9901 0.4302
C3H/HeJ m 0.7844 0.1424 1.0643 0.5044
C57BL/10J f 0.7235 0.1424 1.0035 0.4435
C57BL/10J m 1.6914 0.1522 1.9907 1.3921
C57BL/6J f 1.1919 0.1522 1.4911 0.8926
C57BL/6J m 1.304 0.1117 1.5236 1.0844
C57BLKS/J f 1.1436 0.1215 1.3824 0.9049
C57BLKS/J m 1.3538 0.1424 1.6337 1.0738
C57BR/cdJ f 0.805 0.1644 1.1283 0.4817
C57BR/cdJ m 1.1389 0.1424 1.4188 0.8589
C57L/J f 1.1114 0.1424 1.3913 0.8314
C57L/J m 1.555 0.1424 1.835 1.275
CBA/J f 1.2575 0.1424 1.5375 0.9775
CBA/J m 1.0448 0.1424 1.3247 0.7648
CE/J f 1.0386 0.1424 1.3186 0.7587
CE/J m 0.5728 0.1343 0.8367 0.3088
DBA/1J f 1.1718 0.1274 1.4222 0.9214
DBA/1J m 1.7938 0.1424 2.0737 1.5138
DBA/2J f 1.1544 0.1424 1.4343 0.8744
DBA/2J m 1.0595 0.1274 1.3099 0.8091
FVB/NJ f 0.6147 0.1424 0.8947 0.3348
FVB/NJ m 1.026 0.1522 1.3253 0.7267
I/LnJ f 1.1637 0.1522 1.463 0.8644
I/LnJ m 1.308 0.1801 1.6621 0.9539
KK/HlJ f 0.9437 0.1424 1.2237 0.6638
KK/HlJ m 0.8337 0.1644 1.1569 0.5104
LP/J f 0.275 0.1424 0.555 0.0
LP/J m 0.3225 0.1424 0.6025 0.0425
NOD/ShiLtJ f 0.9041 0.1424 1.1841 0.6242
NOD/ShiLtJ m 0.8826 0.1424 1.1626 0.6027
NON/ShiLtJ f 0.5136 0.1424 0.7936 0.2337
NON/ShiLtJ m 0.5086 0.1424 0.7886 0.2287
NZW/LacJ f 1.4173 0.1424 1.6972 1.1373
NZW/LacJ m 0.6721 0.1424 0.9521 0.3922
PL/J f 0.4418 0.1424 0.7217 0.1618
PL/J m 0.1145 0.1424 0.3945 0.0
RIIIS/J f 0.9283 0.1424 1.2082 0.6483
RIIIS/J m 0.6735 0.1424 0.9535 0.3935
SJL/J f 0.6053 0.1424 0.8852 0.3253
SJL/J m 0.5993 0.1424 0.8792 0.3193
SM/J f 1.2888 0.1424 1.5687 1.0088
SM/J m 1.3322 0.1424 1.6122 1.0523
SWR/J f 0.512 0.1424 0.792 0.232
SWR/J m 1.4197 0.1343 1.6836 1.1557


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.3252 0.1007 1.5231 1.1272
A/J both 1.4342 0.1007 1.6321 1.2362
AKR/J both 0.9394 0.1007 1.1374 0.7415
BALB/cByJ both 0.7354 0.1007 0.9334 0.5375
BALB/cJ both 0.8568 0.0901 1.0339 0.6797
BTBR T+ Itpr3tf/J both 1.5263 0.1007 1.7242 1.3283
BUB/BnJ both 1.3624 0.1042 1.5673 1.1575
C3H/HeJ both 0.7472 0.1007 0.9452 0.5493
C57BL/10J both 1.2075 0.1042 1.4124 1.0026
C57BL/6J both 1.2479 0.0944 1.4335 1.0623
C57BLKS/J both 1.2487 0.0936 1.4327 1.0647
C57BR/cdJ both 0.9719 0.1088 1.1858 0.7581
C57L/J both 1.3332 0.1007 1.5311 1.1352
CBA/J both 1.1511 0.1007 1.3491 0.9532
CE/J both 0.8057 0.0979 0.9981 0.6133
DBA/1J both 1.4828 0.0955 1.6706 1.295
DBA/2J both 1.1069 0.0955 1.2947 0.9191
FVB/NJ both 0.8204 0.1042 1.0253 0.6155
I/LnJ both 1.2359 0.1179 1.4677 1.004
KK/HlJ both 0.8887 0.1088 1.1025 0.6749
LP/J both 0.2987 0.1007 0.4967 0.1008
NOD/ShiLtJ both 0.8934 0.1007 1.0913 0.6954
NON/ShiLtJ both 0.5111 0.1007 0.7091 0.3132
NZW/LacJ both 1.0447 0.1007 1.2426 0.8467
PL/J both 0.2781 0.1007 0.4761 0.0802
RIIIS/J both 0.8009 0.1007 0.9988 0.6029
SJL/J both 0.6023 0.1007 0.8002 0.4043
SM/J both 1.3105 0.1007 1.5085 1.1125
SWR/J both 0.9658 0.0979 1.1582 0.7735




  GWAS USING LINEAR MIXED MODELS