Project measure / variable:   Berndt2   penh_mch5

ID, description, units MPD:35162   penh_mch5   enhanced pause    5 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - enhanced pause 5 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means1.10   None 1.27   None
Median of the strain means1.04   None 1.15   None
SD of the strain means± 0.297 ± 0.513
Coefficient of variation (CV)0.270 0.404
Min–max range of strain means0.544   –   1.80   None 0.627   –   2.71   None
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.8692 2.8692 14.2463 0.0002
strain 28 60.1574 2.1485 10.6676 < 0.0001
sex:strain 28 17.0124 0.6076 3.0168 < 0.0001
Residuals 412 82.9776 0.2014


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.98 0.165   8 0.0583 0.168 0.793, 1.22 -0.4
129S1/SvImJ m 1.44 0.317   8 0.112 0.22 1.1, 2.03 0.33
A/J f 1.72 0.633   8 0.224 0.367 0.992, 2.67 2.09
A/J m 1.66 0.481   8 0.17 0.29 1.08, 2.29 0.76
AKR/J f 1.38 0.528   8 0.187 0.382 0.717, 2.5 0.94
AKR/J m 2.71 1.28   8 0.451 0.472 1.32, 5.18 2.81
BALB/cByJ f 1.26 0.559   8 0.198 0.445 0.603, 2.31 0.54
BALB/cByJ m 0.627 0.113   8 0.0399 0.18 0.49, 0.84 -1.25
BALB/cJ f 0.845 0.288   10 0.0912 0.341 0.408, 1.43 -0.86
BALB/cJ m 1.03 0.254   10 0.0802 0.245 0.644, 1.51 -0.47
BTBR T+ Itpr3tf/J f 1.26 0.316   8 0.112 0.25 0.815, 1.56 0.54
BTBR T+ Itpr3tf/J m 1.6 0.638   8 0.225 0.399 0.939, 2.57 0.65
BUB/BnJ f 1.37 0.637   7 0.241 0.466 0.566, 2.64 0.91
BUB/BnJ m 2.01 0.427   8 0.151 0.212 1.44, 2.67 1.44
C3H/HeJ f 1.05 0.383   8 0.135 0.367 0.57, 1.73 -0.17
C3H/HeJ m 1.22 0.331   8 0.117 0.271 0.797, 1.73 -0.1
C57BL/10J f 0.898 0.249   8 0.0879 0.277 0.503, 1.26 -0.68
C57BL/10J m 0.824 0.123   7 0.0466 0.15 0.639, 1.05 -0.87
C57BL/6J f 0.891 0.137   7 0.0516 0.153 0.755, 1.12 -0.7
C57BL/6J m 0.938 0.273   13 0.0756 0.291 0.605, 1.41 -0.65
C57BLKS/J f 0.56 0.163   11 0.0491 0.291 0.34, 0.827 -1.82
C57BLKS/J m 0.827 0.158   8 0.0559 0.191 0.623, 1.13 -0.86
C57BR/cdJ f 1.1 0.634   6 0.259 0.575 0.42, 1.99 0.0
C57BR/cdJ m 0.636 0.301   8 0.106 0.473 0.33, 1.13 -1.23
C57L/J f 0.705 0.0808   8 0.0286 0.115 0.632, 0.868 -1.33
C57L/J m 1.05 0.656   8 0.232 0.621 0.529, 2.51 -0.43
CBA/J f 0.951 0.177   8 0.0625 0.186 0.654, 1.24 -0.5
CBA/J m 1.23 0.215   8 0.0761 0.175 0.952, 1.6 -0.08
CE/J f 0.544 0.125   8 0.0443 0.231 0.37, 0.78 -1.87
CE/J m 0.63 0.291   9 0.0971 0.463 0.38, 1.13 -1.25
DBA/1J f 0.977 0.347   10 0.11 0.355 0.59, 1.58 -0.42
DBA/1J m 1.16 0.416   8 0.147 0.359 0.596, 1.99 -0.21
DBA/2J f 0.906 0.099   8 0.035 0.109 0.773, 1.03 -0.65
DBA/2J m 1.15 0.348   10 0.11 0.304 0.821, 2.0 -0.23
FVB/NJ f 0.959 0.221   8 0.0781 0.23 0.654, 1.19 -0.48
FVB/NJ m 1.35 0.489   7 0.185 0.362 0.542, 1.91 0.16
I/LnJ f 1.4 0.704   7 0.266 0.502 0.82, 2.91 1.01
I/LnJ m 1.55 0.378   5 0.169 0.245 1.17, 2.16 0.55
KK/HlJ f 1.8 1.1   8 0.387 0.61 0.933, 3.92 2.36
KK/HlJ m 2.43 1.33   6 0.545 0.55 0.766, 3.95 2.26
LP/J f 1.14 0.551   8 0.195 0.485 0.656, 2.0 0.13
LP/J m 0.91 0.27   8 0.0956 0.297 0.57, 1.48 -0.7
NOD/ShiLtJ f 1.04 0.425   8 0.15 0.41 0.478, 1.89 -0.2
NOD/ShiLtJ m 0.882 0.197   8 0.0698 0.224 0.467, 1.06 -0.76
NON/ShiLtJ f 1.32 0.439   8 0.155 0.332 0.899, 2.09 0.74
NON/ShiLtJ m 1.05 0.319   8 0.113 0.305 0.602, 1.54 -0.43
NZW/LacJ f 1.21 0.317   8 0.112 0.262 0.738, 1.77 0.37
NZW/LacJ m 1.13 0.342   8 0.121 0.302 0.77, 1.83 -0.27
PL/J f 1.0 0.151   8 0.0533 0.15 0.862, 1.32 -0.34
PL/J m 1.38 0.434   8 0.154 0.314 0.891, 2.03 0.22
RIIIS/J f 1.43 0.272   8 0.096 0.19 1.01, 1.91 1.11
RIIIS/J m 1.12 0.31   8 0.11 0.277 0.686, 1.55 -0.29
SJL/J f 1.31 0.334   8 0.118 0.255 0.709, 1.64 0.71
SJL/J m 2.09 0.637   8 0.225 0.304 1.31, 3.11 1.6
SM/J f 0.904 0.199   8 0.0703 0.22 0.656, 1.19 -0.66
SM/J m 0.963 0.479   8 0.17 0.498 0.349, 1.98 -0.6
SWR/J f 0.993 0.25   8 0.0885 0.252 0.707, 1.34 -0.36
SWR/J m 1.21 0.156   9 0.052 0.129 0.959, 1.45 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.9795 0.1587 1.2914 0.6676
129S1/SvImJ m 1.445 0.1587 1.7569 1.1331
A/J f 1.724 0.1587 2.0359 1.4121
A/J m 1.66 0.1587 1.9719 1.3481
AKR/J f 1.3834 0.1587 1.6953 1.0715
AKR/J m 2.705 0.1587 3.0169 2.3931
BALB/cByJ f 1.2561 0.1587 1.568 0.9442
BALB/cByJ m 0.6275 0.1587 0.9394 0.3156
BALB/cJ f 0.8448 0.1419 1.1238 0.5658
BALB/cJ m 1.034 0.1419 1.313 0.755
BTBR T+ Itpr3tf/J f 1.2647 0.1587 1.5766 0.9529
BTBR T+ Itpr3tf/J m 1.598 0.1587 1.9099 1.2861
BUB/BnJ f 1.368 0.1696 1.7014 1.0346
BUB/BnJ m 2.0125 0.1587 2.3244 1.7006
C3H/HeJ f 1.0451 0.1587 1.357 0.7332
C3H/HeJ m 1.2228 0.1587 1.5346 0.9109
C57BL/10J f 0.8979 0.1587 1.2098 0.586
C57BL/10J m 0.824 0.1696 1.1574 0.4906
C57BL/6J f 0.8911 0.1696 1.2246 0.5577
C57BL/6J m 0.9376 0.1245 1.1823 0.6929
C57BLKS/J f 0.5602 0.1353 0.8262 0.2942
C57BLKS/J m 0.8268 0.1587 1.1386 0.5149
C57BR/cdJ f 1.103 0.1832 1.4631 0.7429
C57BR/cdJ m 0.636 0.1587 0.9479 0.3241
C57L/J f 0.7053 0.1587 1.0171 0.3934
C57L/J m 1.055 0.1587 1.3669 0.7431
CBA/J f 0.9514 0.1587 1.2633 0.6395
CBA/J m 1.2328 0.1587 1.5446 0.9209
CE/J f 0.5436 0.1587 0.8555 0.2317
CE/J m 0.63 0.1496 0.9241 0.3359
DBA/1J f 0.977 0.1419 1.256 0.698
DBA/1J m 1.1579 0.1587 1.4698 0.846
DBA/2J f 0.906 0.1587 1.2179 0.5941
DBA/2J m 1.1459 0.1419 1.4249 0.8669
FVB/NJ f 0.9594 0.1587 1.2713 0.6475
FVB/NJ m 1.3524 0.1696 1.6859 1.019
I/LnJ f 1.4014 0.1696 1.7349 1.068
I/LnJ m 1.546 0.2007 1.9405 1.1515
KK/HlJ f 1.7956 0.1587 2.1075 1.4837
KK/HlJ m 2.4277 0.1832 2.7878 2.0675
LP/J f 1.1371 0.1587 1.449 0.8252
LP/J m 0.9096 0.1587 1.2215 0.5977
NOD/ShiLtJ f 1.0367 0.1587 1.3486 0.7249
NOD/ShiLtJ m 0.8823 0.1587 1.1941 0.5704
NON/ShiLtJ f 1.3236 0.1587 1.6355 1.0117
NON/ShiLtJ m 1.0454 0.1587 1.3573 0.7335
NZW/LacJ f 1.2106 0.1587 1.5225 0.8987
NZW/LacJ m 1.13 0.1587 1.4419 0.8181
PL/J f 1.0044 0.1587 1.3163 0.6925
PL/J m 1.3838 0.1587 1.6956 1.0719
RIIIS/J f 1.4262 0.1587 1.7381 1.1144
RIIIS/J m 1.1183 0.1587 1.4301 0.8064
SJL/J f 1.3116 0.1587 1.6235 0.9997
SJL/J m 2.095 0.1587 2.4069 1.7831
SM/J f 0.9041 0.1587 1.216 0.5922
SM/J m 0.9628 0.1587 1.2746 0.6509
SWR/J f 0.9934 0.1587 1.3053 0.6815
SWR/J m 1.2132 0.1496 1.5073 0.9192


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.2122 0.1122 1.4328 0.9917
A/J both 1.692 0.1122 1.9125 1.4715
AKR/J both 2.0442 0.1122 2.2647 1.8236
BALB/cByJ both 0.9418 0.1122 1.1624 0.7213
BALB/cJ both 0.9394 0.1003 1.1367 0.7421
BTBR T+ Itpr3tf/J both 1.4314 0.1122 1.6519 1.2108
BUB/BnJ both 1.6902 0.1161 1.9185 1.462
C3H/HeJ both 1.1339 0.1122 1.3545 0.9134
C57BL/10J both 0.8609 0.1161 1.0892 0.6327
C57BL/6J both 0.9144 0.1052 1.1212 0.7076
C57BLKS/J both 0.6935 0.1043 0.8984 0.4885
C57BR/cdJ both 0.8695 0.1212 1.1077 0.6313
C57L/J both 0.8801 0.1122 1.1007 0.6596
CBA/J both 1.0921 0.1122 1.3126 0.8715
CE/J both 0.5868 0.109 0.8011 0.3725
DBA/1J both 1.0674 0.1064 1.2767 0.8582
DBA/2J both 1.0259 0.1064 1.2352 0.8167
FVB/NJ both 1.1559 0.1161 1.3842 0.9276
I/LnJ both 1.4737 0.1314 1.732 1.2154
KK/HlJ both 2.1116 0.1212 2.3499 1.8734
LP/J both 1.0234 0.1122 1.2439 0.8028
NOD/ShiLtJ both 0.9595 0.1122 1.18 0.739
NON/ShiLtJ both 1.1845 0.1122 1.405 0.964
NZW/LacJ both 1.1703 0.1122 1.3909 0.9498
PL/J both 1.1941 0.1122 1.4146 0.9735
RIIIS/J both 1.2722 0.1122 1.4928 1.0517
SJL/J both 1.7033 0.1122 1.9239 1.4828
SM/J both 0.9334 0.1122 1.154 0.7129
SWR/J both 1.1033 0.109 1.3176 0.889




  GWAS USING LINEAR MIXED MODELS