Brugnara1: Erythrocyte cation content and transport in 10 inbred strains of mice (2013)

Rivera A, Zee RY, Alper SL, Peters LL, Brugnara C. Strain-specific variations in cation content and transport in mouse erythrocytes. Physiol Genomics. 2013 May 1;45(9):343-50. doi: 10.1152/physiolgenomics.00143.2012. Epub 2013 Mar 12.   PubMed 23482811  


         
Brugnara1 downloads
• Download Brugnara1 project data set     one row per animal, one column per trait
• Download Brugnara1 strain means, SD, N, etc.     one row per strain/sex/measure
Ontology terms mapped to Brugnara1 measures:
    MA:0000059   blood
    MP:0000226   abnormal mean corpuscular volume
    MP:0001589   abnormal mean corpuscular hemoglobin
    MP:0004231   abnormal calcium ion homeostasis
    MP:0005640   abnormal mean corpuscular hemoglobin concentration
    MP:0011913   abnormal reticulocyte cell number
    MP:0011978   abnormal potassium ion homeostasis
    MP:0012373   abnormal erythrocyte magnesium ion content
    MP:0012376   abnormal erythrocyte potassium ion content
    MP:0012379   abnormal erythrocyte sodium ion content
    MP:0012385   abnormal erythrocyte potassium:chloride symporter activity
    MP:0012388   abnormal erythrocyte sodium:hydrogen antiporter activity
    MP:0012391   abnormal erythrocyte sodium:potassium-exchanging ATPase activity
    MP:0012394   abnormal erythrocyte calcium-activated potassium channel activity
    MP:0012397   abnormal nucleated erythrocyte cell number
    VT:0000248   erythrocyte size trait
    VT:0001562   blood calcium amount
    VT:0001588   blood hemoglobin amount
    VT:0001771   blood magnesium amount
    VT:0001776   blood sodium amount
    VT:0002447   erythrocyte morphology trait
    VT:0002668   blood potassium amount
    VT:0003018   blood chloride amount
    VT:0003135   reticulocyte quantity
    VT:0004152   blood iron amount
    VT:0010534   erythrocyte ion transport trait
    VT:0010535   erythrocyte ion amount
Participants Carlo Brugnara       Harvard Medical School,  Boston, MA
Luanne L Peters       The Jackson Laboratory,  Bar Harbor, ME
With: Rivera A, Zee RY, Alper SL
ContactCarlo Brugnara     Carlo.Brugnara@childrens.harvard.edu
AcknowledgementsFunding provided by NIH HL085480, HL081497, HL090632, CA34196
Project type Phenotype strain survey data set
MPD identifiersBrugnara1     MPD:474
Data changelog No updates/corrections.       Initial release date: 05/2013.
Formatted citation
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Summary of procedures that were conducted
• complete blood count Hematology.
• ion transport assessment Hematology red cell ion content, ion transport.
Mice: inbred   10 strains   ♀♂   age 8wks   1 cohort