Project measure / variable:   Brugnara1   potassium

ID, description, units MPD:47402   potassium   RBC potassium cation content (mmol/kg hemoglobin)   [mmol/kg]  
Data set, strains Brugnara1   inbred   10 strains     sex: both     age: 8wks
Procedure ion transport assessment
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  STRAIN COMPARISON PLOT
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Brugnara1 - RBC potassium cation content (mmol/kg hemoglobin)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means389   mmol/kg 414   mmol/kg
Median of the strain means386   mmol/kg 415   mmol/kg
SD of the strain means± 30.0 ± 18.1
Coefficient of variation (CV)0.0772 0.0436
Min–max range of strain means351   –   453   mmol/kg 382   –   443   mmol/kg
Mean sample size per strain31.2   mice 31.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 104319.6447 104319.6447 67.6771 < 0.0001
strain 9 264980.2408 29442.249 19.1006 < 0.0001
sex:strain 9 88737.2709 9859.6968 6.3965 < 0.0001
Residuals 603 929483.5332 1541.4321


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 375.0 20.4   33 3.55 0.0543 329.0, 427.0 -0.46
129S1/SvImJ m 396.0 53.9   34 9.24 0.136 270.0, 483.0 -1.0
A/J f 365.0 32.1   33 5.59 0.0879 310.0, 413.0 -0.79
A/J m 421.0 75.0   30 13.7 0.178 336.0, 670.0 0.39
BALB/cJ f 378.0 22.1   26 4.33 0.0585 333.0, 410.0 -0.36
BALB/cJ m 382.0 24.2   30 4.43 0.0634 334.0, 428.0 -1.77
C3H/HeJ f 351.0 21.7   30 3.96 0.0619 304.0, 388.0 -1.26
C3H/HeJ m 402.0 30.2   30 5.51 0.0751 265.0, 438.0 -0.66
C57BL/6J f 394.0 53.9   35 9.11 0.137 259.0, 495.0 0.17
C57BL/6J m 436.0 60.1   33 10.5 0.138 276.0, 609.0 1.22
C57BLKS/J f 453.0 28.4   32 5.03 0.0629 406.0, 525.0 2.14
C57BLKS/J m 443.0 31.1   39 4.97 0.0701 373.0, 508.0 1.61
CBA/J f 419.0 26.1   32 4.61 0.0623 379.0, 475.0 1.01
CBA/J m 412.0 44.3   34 7.6 0.108 307.0, 503.0 -0.11
DBA/2J f 396.0 27.8   30 5.08 0.0702 337.0, 471.0 0.24
DBA/2J m 410.0 33.2   22 7.08 0.081 326.0, 454.0 -0.22
NZW/LacJ f 363.0 38.0   32 6.72 0.105 287.0, 406.0 -0.86
NZW/LacJ m 418.0 26.0   28 4.92 0.0622 374.0, 465.0 0.22
SM/J f 394.0 46.2   28 8.72 0.117 350.0, 509.0 0.17
SM/J m 420.0 29.4   32 5.19 0.07 374.0, 476.0 0.33


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 374.887 6.8345 388.3092 361.4647
129S1/SvImJ m 395.7241 6.7332 408.9475 382.5007
A/J f 365.3779 6.8345 378.8001 351.9556
A/J m 420.9207 7.1681 434.9981 406.8433
BALB/cJ f 377.5019 7.6997 392.6235 362.3804
BALB/cJ m 382.2583 7.1681 396.3357 368.1809
C3H/HeJ f 350.626 7.1681 364.7034 336.5486
C3H/HeJ m 401.789 7.1681 415.8664 387.7116
C57BL/6J f 394.436 6.6363 407.4691 381.4029
C57BL/6J m 435.7285 6.8345 449.1508 422.3062
C57BLKS/J f 452.5384 6.9404 466.1688 438.9081
C57BLKS/J m 443.1354 6.2868 455.4821 430.7887
CBA/J f 419.0122 6.9404 432.6426 405.3818
CBA/J m 411.8932 6.7332 425.1166 398.6698
DBA/2J f 396.1943 7.1681 410.2717 382.1169
DBA/2J m 410.0427 8.3705 426.4816 393.6039
NZW/LacJ f 362.8969 6.9404 376.5273 349.2665
NZW/LacJ m 418.3975 7.4196 432.969 403.826
SM/J f 393.6936 7.4196 408.2651 379.1221
SM/J m 419.9263 6.9404 433.5566 406.2959


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 385.3055 4.797 394.7265 375.8846
A/J both 393.1493 4.952 402.8746 383.4239
BALB/cJ both 379.8801 5.2599 390.2101 369.5501
C3H/HeJ both 376.2075 5.0686 386.1617 366.2533
C57BL/6J both 415.0822 4.7632 424.4367 405.7278
C57BLKS/J both 447.8369 4.6822 457.0324 438.6414
CBA/J both 415.4527 4.8349 424.948 405.9574
DBA/2J both 403.1185 5.5101 413.9399 392.2972
NZW/LacJ both 390.6472 5.0799 400.6236 380.6708
SM/J both 406.8099 5.0799 416.7863 396.8335




  GWAS USING LINEAR MIXED MODELS