Project measure / variable:   Brugnara1   Na_K_pump


  STRAIN COMPARISON PLOT
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Brugnara1 - RBC sodium-potassium pump (Na-K; per 1013 cells)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means30.1   mmol⋅h 29.4   mmol⋅h
Median of the strain means29.8   mmol⋅h 31.8   mmol⋅h
SD of the strain means± 4.51 ± 8.58
Coefficient of variation (CV)0.150 0.292
Min–max range of strain means22.6   –   37.1   mmol⋅h 12.7   –   39.4   mmol⋅h
Mean sample size per strain10.5   mice 10.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 29.1764 29.1764 1.5436 0.2156
strain 9 5391.0045 599.0005 31.6915 < 0.0001
sex:strain 9 3329.1619 369.9069 19.5708 < 0.0001
Residuals 193 3647.8909 18.901


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 27.1 4.38   11 1.32 0.162 21.1, 36.8 -0.67
129S1/SvImJ m 31.2 5.72   12 1.65 0.183 19.1, 40.9 0.21
A/J f 32.9 4.91   12 1.42 0.149 25.2, 40.9 0.61
A/J m 32.5 7.0   12 2.02 0.215 25.0, 46.0 0.37
BALB/cJ f 35.2 5.46   11 1.65 0.155 28.1, 41.9 1.12
BALB/cJ m 35.5 3.79   12 1.09 0.107 27.6, 40.8 0.72
C3H/HeJ f 33.5 7.32   10 2.32 0.218 24.9, 48.7 0.75
C3H/HeJ m 32.3 3.26   10 1.03 0.101 27.6, 37.6 0.34
C57BL/6J f 37.1 3.29   12 0.949 0.0886 31.4, 43.7 1.54
C57BL/6J m 39.4 3.29   10 1.04 0.0834 33.0, 43.5 1.17
C57BLKS/J f 29.7 5.05   10 1.6 0.17 19.1, 35.0 -0.1
C57BLKS/J m 12.7 1.81   10 0.572 0.142 10.9, 17.2 -1.94
CBA/J f 29.8 2.46   10 0.779 0.0825 26.0, 33.8 -0.08
CBA/J m 15.2 3.83   10 1.21 0.251 11.3, 21.7 -1.65
DBA/2J f 26.2 3.22   10 1.02 0.123 21.6, 30.9 -0.87
DBA/2J m 34.0 4.33   11 1.31 0.127 27.6, 43.1 0.54
NZW/LacJ f 27.3 4.18   10 1.32 0.153 20.1, 35.3 -0.63
NZW/LacJ m 29.9 1.95   10 0.616 0.0651 26.2, 32.7 0.06
SM/J f 22.6 2.76   10 0.874 0.122 18.5, 28.0 -1.67
SM/J m 30.9 2.49   10 0.787 0.0806 28.1, 35.0 0.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 27.0727 1.3108 29.6581 24.4873
129S1/SvImJ m 31.2 1.255 33.6753 28.7247
A/J f 32.9483 1.255 35.4237 30.473
A/J m 32.5342 1.255 35.0095 30.0588
BALB/cJ f 35.2082 1.3108 37.7936 32.6228
BALB/cJ m 35.5425 1.255 38.0178 33.0672
C3H/HeJ f 33.54 1.3748 36.2516 30.8284
C3H/HeJ m 32.305 1.3748 35.0166 29.5934
C57BL/6J f 37.1108 1.255 39.5862 34.6355
C57BL/6J m 39.416 1.3748 42.1276 36.7044
C57BLKS/J f 29.747 1.3748 32.4586 27.0354
C57BLKS/J m 12.701 1.3748 15.4126 9.9894
CBA/J f 29.842 1.3748 32.5536 27.1304
CBA/J m 15.222 1.3748 17.9336 12.5104
DBA/2J f 26.179 1.3748 28.8906 23.4674
DBA/2J m 33.9636 1.3108 36.549 31.3782
NZW/LacJ f 27.326 1.3748 30.0376 24.6144
NZW/LacJ m 29.928 1.3748 32.6396 27.2164
SM/J f 22.64 1.3748 25.3516 19.9284
SM/J m 30.906 1.3748 33.6176 28.1944


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 29.1364 0.9074 30.926 27.3467
A/J both 32.7413 0.8874 34.4916 30.9909
BALB/cJ both 35.3753 0.9074 37.165 33.5857
C3H/HeJ both 32.9225 0.9721 34.8399 31.0051
C57BL/6J both 38.2634 0.9307 40.0992 36.4277
C57BLKS/J both 21.224 0.9721 23.1414 19.3066
CBA/J both 22.532 0.9721 24.4494 20.6146
DBA/2J both 30.0713 0.9498 31.9446 28.198
NZW/LacJ both 28.627 0.9721 30.5444 26.7096
SM/J both 26.773 0.9721 28.6904 24.8556




  GWAS USING LINEAR MIXED MODELS